Taurine
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Evidence Summary
Taurine is a semi-essential amino acid that plays a critical role in cardiovascular regulation, metabolic homeostasis, and neonatal development. Research indicates significant potential for its use in managing blood pressure, lipid profiles, and certain heart conditions.
Evidence by Condition
Meta-analyses and RCTs demonstrate that taurine can lower blood pressure, improve vascular function, and potentially benefit patients with heart failure or dilated cardiomyopathy.
Evidence suggests taurine is vital for the growth and development of preterm or low birth weight infants.
Research indicates taurine plays a role in regulating glucose and lipid metabolism, as well as managing obesity.
Effective Doses
6g/day has been studied for specific uses such as portal hypertension (PMID: 29105115).
Key Findings
- Taurine supplementation lowers blood pressure and improves vascular function in individuals with prehypertension (PMID: 26781281).
- Meta-analyses support the cardiovascular benefits of taurine, including improvements in blood pressure and lipid profiles (PMID: 30006901, 32871172).
- Taurine is essential for the growth and development of preterm or low birth weight infants (PMID: 17943882).
- Taurine supplementation may improve functional capacity and myocardial oxygen consumption in patients with heart failure (PMID: 28118062).
Limitations
Much of the clinical evidence is derived from small sample sizes (e.g., N=8 or N=12) or focuses on highly specific populations like neonates or patients with existing heart failure.
Safety & Interactions
No specific contraindications or drug interactions were identified in the provided research abstracts.
AI-generated summary from 35 peer-reviewed studies. Not medical advice. Always consult a healthcare provider.
Claims vs. Evidence
| Claim Type | % of Products | Evidence Required | Status |
|---|---|---|---|
| All Other | 100% | Tier D (Unclassified) | ✅ Supported |
| Structure/Function | 76% | Tier C (DSHEA Structure/Function (no pre-approval)) | ✅ Supported |
| Nutrient | 24% | Tier D (Unknown) | ✅ Supported |
Research by Topic
Research Evidence (35)
BACKGROUND: Branched-chain amino acids (BCAAs) play a vital role in neonatal nutrition. Optimal BCAA supplementation might improve neonatal nutrient storage, leading to better physical and neurological development and other outcomes. OBJECTIVES: To d...
BACKGROUND: Taurine is the most abundant free amino acid in breast milk. Evidence exists that taurine has important roles in intestinal fat absorption, hepatic function, and auditory and visual development in preterm or low birth weight infants. Obse...
**Tzang et al., 2024** | Nutr J | Meta Analysis Tzang Chih-Chen, Lin Wei-Chen, ... Özçakar Levent. Insights into the cardiovascular benefits of taurine: a systematic review and meta-analysis. Nutr J. 2024-Aug-15;23(1):93. doi:10.1186/s12937-024-00995...
PURPOSE OF REVIEW: The aims of this meta-analysis were to investigate the effects of orally administered isolated taurine on resting systolic blood pressure (SBP) and diastolic blood pressure (DBP) in humans. RECENT FINDINGS: There is growing evidenc...
The purpose of this study was to determine the effects of pre-exercise amino acid (AA) supplementation on post-exercise iron regulation. Ten healthy males participated under two different sets of conditions in a randomized, double-blind, crossover de...
Taurine plays a pivotal role in regulating glucose and lipid metabolism, blood pressure homeostasis, and obesity largely due to its cytoprotective, antioxidant, and anti-inflammatory actions. Despite promising data from animal studies in this scenari...
Background: Taurine, 2-aminoethanesulfonic acid, is an amino acid found in animal products. Taurine is produced for human consumption as a supplement and ingredient in beverages. Supplementation is a safe, inexpensive, and effective treatment for dil...
**Salem et al., 2024** | Sports Med Open | Systematic Review Salem Atef, Ben Maaoui Khouloud, ... Chtourou Hamdi. Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) S...
The green tea amino acid, L-theanine (L-THE) is associated with several health benefits, including improvements in mood, cognition and a reduction of stress and anxiety-like symptoms. This systematic review evaluated the effect of pure L-THE intake, ...
Taurine, the most abundant, semiessential, sulfur-containing amino acid, is well known to lower blood pressure (BP) in hypertensive animal models. However, no rigorous clinical trial has validated whether this beneficial effect of taurine occurs in h...
BACKGROUND: Distinct circulating bile acid (BA) subtypes may play roles in regulating lipid homeostasis and atherosclerosis. OBJECTIVES: We investigated whether changes in circulating BA subtypes induced by weight-loss dietary interventions were asso...
BACKGROUND: Maintaining adequate hydration is critical to optimal health, well-being, and performance. Those who are physically active in stressful environments, such as warm and/or humid scenarios, may be at particular risk for dehydration with ensu...
BACKGROUND: Taurine is an amino acid found abundantly in the heart in very high concentrations. It is assumed that taurine contributes to several physiological functions of mammalian cells, such as osmoregulation, anti-inflammation, membrane stabiliz...
BACKGROUND: The amino sulphonic acid taurine reduces oxidative endoplasmatic reticulum stress and inhibits hepatic stellate cell activation, which might lead to reduction of portal pressure in cirrhosis. AIM: To assess the haemodynamic effects of tau...
**NCT ID**: NCT06613542 **Phase**: NA **Status**: COMPLETED **Enrollment**: 90 **Completion**: 2025-11-13
**NCT ID**: NCT04099108 **Phase**: NA **Status**: COMPLETED **Enrollment**: 50 **Completion**: 2022-12-31
**NCT ID**: NCT05733364 **Phase**: NA **Status**: COMPLETED **Enrollment**: 45 **Completion**: 2023-12-03
**NCT ID**: NCT06167772 **Phase**: NA **Status**: COMPLETED **Enrollment**: 40 **Completion**: 2024-05-10
**Beyranvand et al., 2011** | J Cardiol | Rct Beyranvand Mohamad Reza, Khalafi Mahshid Kadkhodai, ... Piranfar Mohammad Asadpour. Effect of taurine supplementation on exercise capacity of patients with heart failure. J Cardiol. 2011-May;57(3):333-7. ...
BACKGROUND: Tolerance development is an important clinical outcome for infants with cow's milk allergy. OBJECTIVE: This multicenter, prospective, randomized, double-blind, controlled clinical study (NTR3725) evaluated tolerance development to cow's m...
OBJECTIVE: To observe the effect of acupuncture combined with rehabilitation training on cognitive function and amino acid metabolism in children with cerebral palsy. METHODS: Twenty children with cerebral palsy (cerebral palsy group) were randomly d...
Amino acid neurotransmitters, including glutamate, phenylalanine, tyrosine, alanine, and glycine, underlie the majority of the excitatory and inhibitory neurotransmission in the nervous system, and acute exercise has been shown to modulate their conc...
The objective of the present study is to assess the rates of acquired tolerance to cow's milk (CM) after 36 months in subjects who consumed amino acid-based formula with synbiotics (AAF-S) or amino acid-based formula without synbiotics (AAF) during a...
Alzheimer's disease (AD) is a neurodegenerative condition characterized by cognitive decline and associated metabolic disturbances, including altered amino acid profiles. This study investigated the effects of probiotic supplementation with Lactobaci...
**NCT ID**: NCT02919670 **Phase**: NA **Status**: COMPLETED **Enrollment**: 114 **Completion**: 2020-07
**NCT ID**: NCT03717935 **Phase**: NA **Status**: COMPLETED **Enrollment**: 27 **Completion**: 2022-01-14
**NCT ID**: NCT04491188 **Phase**: NA **Status**: COMPLETED **Enrollment**: 22 **Completion**: 2018-05-03
**NCT ID**: NCT04701463 **Phase**: NA **Status**: COMPLETED **Enrollment**: 20 **Completion**: 2020-11-25
**Sedova et al., 2010** | Kardiologiia | Rct Sedova E M, Magnitskaia O V. [A clinical experience of taurine and trimetazidine use in premenopausal women with chronic heart failure]. Kardiologiia. 2010;50(1):62-3 *No abstract available* *Requires manu...
**NCT ID**: NCT01412723 **Phase**: PHASE3 **Status**: COMPLETED **Enrollment**: 64 **Completion**: 2012-04
**NCT ID**: NCT01425983 **Phase**: PHASE3 **Status**: COMPLETED **Enrollment**: 80 **Completion**: 2012-06
**NCT ID**: NCT01705782 **Phase**: NA **Status**: COMPLETED **Enrollment**: 8 **Completion**: 2013-12
**NCT ID**: NCT01922167 **Phase**: NA **Status**: COMPLETED **Enrollment**: 19 **Completion**: 2018-12-17
**NCT ID**: NCT02997137 **Phase**: PHASE3 **Status**: COMPLETED **Enrollment**: 74 **Completion**: 2016-02
**Azuma et al., 1985** | Clin Cardiol | Rct Azuma J, Sawamura A, ... Ishiyama T. Therapeutic effect of taurine in congestive heart failure: a double-blind crossover trial. Clin Cardiol. 1985-May;8(5):276-82 In a double-blind, randomized, crossover, p...
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Frequently Asked Questions
What is taurine and what are its main benefits?
Taurine is a semi-essential amino acid that is vital for cardiovascular regulation, metabolic health, and development. There is strong evidence for its benefits in heart health and moderate evidence regarding its role in metabolism and infant growth.
Can taurine help lower blood pressure?
Yes, there is strong evidence from clinical trials and meta-analyses showing that taurine can lower blood pressure and improve vascular function. This effect has been specifically noted in individuals with prehypertension.
Does taurine help with heart failure?
There is strong evidence suggesting that taurine may benefit patients with heart failure or dilated cardiomyopathy. Research indicates it may help improve functional capacity and how the heart uses oxygen.
Can taurine help with weight loss or metabolism?
There is moderate evidence that taurine plays a role in regulating glucose and lipid metabolism. Research also suggests it may play a part in managing obesity.
Is taurine important for babies?
There is moderate evidence that taurine is essential for the growth and development of infants, particularly those who are preterm or have a low birth weight.
What is the effective dose of taurine?
While doses vary depending on the condition, a dose of 6g per day has been studied for specific uses such as portal hypertension. You should consult a healthcare professional to determine the appropriate dose for your needs.
Are there any side effects or drug interactions with taurine?
No specific drug interactions or contraindications have been identified in the current research. However, you should always speak with a doctor before starting a new supplement to ensure it is safe for your specific health profile.
Answers generated from research evidence. Not medical advice.