Olive Leaf
Also known as olea europaea, oleuropein, olive leaf, olive leaf extract
Key takeaways
- Combination of low-dose Monacolin K, Coenzyme Q10, Grape Seed, and Olive Leaf Extracts effectively lowers LDL cholesterol (PMID: 37375586).
- Research has been conducted on the bioavailability of oleuropein in relation to probiotic use (NCT04328571).
- Investigation into its effects on elite athletes and blood pressure reduction is ongoing or completed (NCT06741163, NCT02421835).
What the research shows
AI-synthesized from 5 peer-reviewed sources · Updated 2025
Olive leaf extract is a botanical supplement used for cardiovascular and performance support. Current evidence suggests potential benefits for lipid management when used in combination therapies, though high-quality standalone data is limited.
By condition
Dyslipidemia
Moderate
Olive leaf extract, as part of a combination therapy with Monacolin K, CoQ10, and grape seed extract, contributed to the lowering of LDL cholesterol.
Blood Pressure
Insufficient
A clinical trial investigated its role in blood pressure reduction, but specific outcome data was not provided in the abstract.
Athletic Performance
Insufficient
Recent trials have explored its effects on elite cyclists and handball players, but results are not yet detailed.
Effective doses
Not specified in the provided abstracts.
Safety & interactions
No specific interactions or contraindications were mentioned in the provided text.
Limitations
The majority of provided sources are clinical trial registrations rather than published peer-reviewed results. There is a lack of standalone RCTs focusing solely on olive leaf extract.
Top-rated Olive Leaf products
Ranked by safety score and evidence coverage
How it's sold
Data aggregated from 151 product labels
Research evidence
Showing top 10 of 5 sources, sorted by quality
**Angelopoulos et al., 2023** | Nutrients | Rct Angelopoulos Nicholas, Paparodis Rodis D, ... Livadas Sarantis. Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mil…
**NCT ID**: NCT06741163 **Phase**: NA **Status**: COMPLETED **Enrollment**: 28 **Completion**: 2025-01-14
**NCT ID**: NCT07371052 **Phase**: NA **Status**: COMPLETED **Enrollment**: 18 **Completion**: 2025-02-01
**NCT ID**: NCT04328571 **Phase**: NA **Status**: COMPLETED **Enrollment**: 104 **Completion**: 2021-09-15
**NCT ID**: NCT02421835 **Phase**: NA **Status**: COMPLETED **Enrollment**: 120 **Completion**: 2016-04
Frequently asked questions
What is Olive Leaf Extract and what is it used for?
Olive leaf extract is a botanical supplement primarily used for cardiovascular support and lipid management. Current evidence suggests it may help lower LDL cholesterol when used as part of a combination therapy with other ingredients like Monacolin K and CoQ10. However, high-quality standalone data for most conditions is limited.
Does Olive Leaf Extract work for lowering cholesterol?
There is moderate evidence that olive leaf extract contributes to lowering LDL cholesterol when taken as part of a combination therapy. Specifically, studies indicate that combining it with Monacolin K, Coenzyme Q10, and grape seed extract can effectively reduce LDL levels. It is not recommended to replace prescribed cholesterol medications with this supplement.
Can Olive Leaf Extract help with high blood pressure?
Evidence regarding olive leaf extract's effect on blood pressure is currently insufficient. While clinical trials have investigated its role in blood pressure reduction, specific outcome data has not been provided in available abstracts. Therefore, research is considered limited for this specific condition.
Does Olive Leaf Extract improve athletic performance?
Research on olive leaf extract for athletic performance is currently insufficient. Recent trials have explored its effects on elite cyclists and handball players, but detailed results are not yet available. Consumers should note that evidence is limited for this use case.
What is the effective dose of Olive Leaf Extract?
Effective doses for olive leaf extract are not specified in the provided evidence summary. Because specific dosage guidelines are missing, it is important to consult a healthcare provider for personalized advice rather than relying on general recommendations.
Is Olive Leaf Extract safe to take with other medications?
No specific drug interactions or contraindications were documented in the provided text. However, because olive leaf extract may influence lipid levels, individuals on cholesterol-lowering medications should consult a healthcare provider before use. Pregnant individuals or those with specific health conditions should also seek professional medical advice.
Who should avoid taking Olive Leaf Extract?
While no specific contraindications are listed, individuals on prescribed medications, particularly for cholesterol or blood pressure, should consult a healthcare provider before use. Pregnant or breastfeeding women should also seek medical guidance, as safety data for these groups is not detailed in the evidence summary.