Astaxanthin is a carotenoid being investigated for its potential anti-inflammatory, anti-fatigue, and skin health benefits. Current research consists of a mix of randomized controlled trials and small-scale clinical trials exploring its impact on cardiovascular health, fertility, and aging.

Evidence by Condition

inflammation Moderate

A multi-nutrient study suggests astaxanthin may contribute to managing inflammation and endothelial function.

cardiovascular health Insufficient

Clinical trials have investigated its potential to reduce exercising heart rate.

skin aging Insufficient

Research is exploring the use of astaxanthin in combination with other antioxidants for the treatment of skin aging.

fatigue Insufficient

Small-scale trials are evaluating the anti-fatigue properties of astaxanthin.

fertility Insufficient

Studies have investigated the effects of oral astaxanthin on semen quality and embryo development.

Effective Doses

Specific effective dose ranges are not clearly established in the provided research, though one study utilized 2 mg as part of a multi-ingredient supplement.

Key Findings

Astaxanthin, as part of a combined nutrient complex, may influence inflammation and endothelial function (PMID: 31987113).
Clinical trials suggest potential for reducing exercising heart rate (NCT05282355).
Research is ongoing regarding its efficacy for anti-fatigue (NCT06593535) and skin aging (NCT03460860).

Limitations

The available evidence is limited by very small sample sizes in most clinical trials and a lack of studies focusing on astaxanthin as a monotherapy.

Safety & Interactions

No specific interactions or contraindications were identified in the provided research summaries.

AI-generated summary from 6 peer-reviewed studies. Not medical advice. Always consult a healthcare provider.

Claims vs. Evidence

50% Evidence-Backed

50% Unsupported

88% Structure/Function

Claim Type	% of Products	Evidence Required	Status
All Other	99%	Tier D (Unclassified)	✅ Supported
Structure/Function	88%	Tier C (DSHEA Structure/Function (no pre-approval))	⚠️ Unsupported
Nutrient	34%	Tier D (Unknown)	✅ Supported
Qualified Health	1%	Tier B (FDA Qualified Health Claim)	⚠️ Unsupported

Research by Topic

Dietary Supplement General 5 studies

CLI Astaxanthin Reduces Exercising Heart Rate.

CLI Effects of Astaxanthin Supplementation

CLI Evaluation of Astaxanthin Properties on Anti-fatigue

+2 more

Cochrane Curcumin Inflammation 1 studies

RCT A combined effect of Cavacurcumin, Eicosapentaenoic acid (Om...

Research Evidence (6)

Clinical Trial: 5 Rct: 1

C A combined effect of Cavacurcumin, Eicosapentaenoic acid (Omega-3s), Astaxanthin and Gamma -linoleic acid (Omega-6) (CEAG) in healthy volunteers- a randomized, double-blind, placebo-controlled study.

Rct Clinical nutrition ESPEN

BACKGROUND: Inflammation plays a key role and is one of the early steps in the pathogenesis of endothelial function, thereby increasing the risk of hypertension (HTN), coronary artery disease (CAD), stroke and several other risk factors of cardiovasc...

PubMed DOI

C Astaxanthin Reduces Exercising Heart Rate.

Clinical Trial ClinicalTrials.gov 2021

**NCT ID**: NCT05282355 **Phase**: NA **Status**: COMPLETED **Enrollment**: 19 **Completion**: 2021-07-02

ClinicalTrials.gov

C Effects of Astaxanthin Supplementation

Clinical Trial ClinicalTrials.gov 2023

**NCT ID**: NCT06511960 **Phase**: NA **Status**: COMPLETED **Enrollment**: 24 **Completion**: 2024-04-15

ClinicalTrials.gov

C Evaluation of Astaxanthin Properties on Anti-fatigue

Clinical Trial ClinicalTrials.gov 2022

**NCT ID**: NCT06593535 **Phase**: NA **Status**: COMPLETED **Enrollment**: 10 **Completion**: 2022-09-20

ClinicalTrials.gov

C Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin Aging

Clinical Trial ClinicalTrials.gov 2018

**NCT ID**: NCT03460860 **Phase**: NA **Status**: COMPLETED **Enrollment**: 100 **Completion**: 2019-02-07

ClinicalTrials.gov

C Oral Astaxanthin and Semen Quality, Fertilization and Embryo Development in Assisted Reproduction Techniques Procedures

Clinical Trial ClinicalTrials.gov 2014

**NCT ID**: NCT02310087 **Phase**: NA **Status**: COMPLETED **Enrollment**: 80 **Completion**: 2019-01

ClinicalTrials.gov

Related Supplements

Vitamin E 1 shared sources Omega 3 1 shared sources Lycopene 1 shared sources

Frequently Asked Questions

What is Astaxanthin and what are its benefits?

Astaxanthin is a type of carotenoid antioxidant. It is currently being researched for its potential roles in supporting skin health, reducing fatigue, and managing inflammation.

Does Astaxanthin help with inflammation?

There is moderate evidence suggesting that astaxanthin may help manage inflammation and support endothelial function. This effect has been observed when it is used as part of a multi-nutrient supplement.

Can Astaxanthin help with skin aging or fatigue?

There is currently insufficient evidence to confirm if astaxanthin is effective for skin aging or fatigue. Clinical trials are still ongoing to evaluate these specific anti-fatigue and anti-aging properties.

Is Astaxanthin good for heart health?

There is insufficient evidence regarding its impact on cardiovascular health. While some clinical trials have investigated its potential to reduce heart rate during exercise, more research is needed.

What is the recommended dose of Astaxanthin?

A specific effective dose range has not been clearly established by current research. One study noted the use of 2 mg as part of a multi-ingredient supplement.

Is Astaxanthin safe to take?

No specific contraindications or safety concerns were identified in the available research. However, you should consult a healthcare professional before adding new supplements to your routine.

Are there any drug interactions with Astaxanthin?

There are currently no documented drug interactions for astaxanthin. Additionally, the research did not identify any specific groups of people who should avoid taking it.

Answers generated from research evidence. Not medical advice.