Astaxanthin
Also known as astareal, astaxanthin, haematococcus, krill astaxanthin
Key takeaways
- Astaxanthin was used as part of a combined formula (CEAG) to target inflammation and endothelial function (PMID: 31987113)
- Research has explored its impact on reducing exercising heart rate (NCT05282355)
- Investigation into its role in improving semen quality and embryo development (NCT02310087)
What the research shows
AI-synthesized from 6 peer-reviewed sources · Updated 2025
Astaxanthin is a potent antioxidant carotenoid. Current research explores its potential benefits across a wide range of applications, including inflammation, athletic performance, skin aging, and reproductive health.
By condition
Inflammation
Weak
Studied as part of a combined supplement (CEAG) to address endothelial function and inflammation risk.
General Health/Performance
Insufficient
Multiple small-scale trials have investigated its effects on heart rate during exercise, anti-fatigue properties, and semen quality, but results are not detailed in the provided abstracts.
Skin Aging
Insufficient
Investigated in combination with lycopene and vitamin E for the treatment of skin aging.
Effective doses
One study utilized a dose of 2 mg of Astaxanthin in combination with other antioxidants for skin aging.
Safety & interactions
No specific interactions or contraindications were mentioned in the provided research summaries.
Limitations
The available evidence is limited by very small sample sizes (some as low as 10 participants) and a lack of detailed outcome data in the provided abstracts.
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Research evidence
Showing top 10 of 6 sources, sorted by quality
BACKGROUND: Inflammation plays a key role and is one of the early steps in the pathogenesis of endothelial function, thereby increasing the risk of hypertension (HTN), coronary artery disease (CAD), stroke and several other risk factors of …
**NCT ID**: NCT05282355 **Phase**: NA **Status**: COMPLETED **Enrollment**: 19 **Completion**: 2021-07-02
**NCT ID**: NCT06511960 **Phase**: NA **Status**: COMPLETED **Enrollment**: 24 **Completion**: 2024-04-15
**NCT ID**: NCT06593535 **Phase**: NA **Status**: COMPLETED **Enrollment**: 10 **Completion**: 2022-09-20
**NCT ID**: NCT03460860 **Phase**: NA **Status**: COMPLETED **Enrollment**: 100 **Completion**: 2019-02-07
**NCT ID**: NCT02310087 **Phase**: NA **Status**: COMPLETED **Enrollment**: 80 **Completion**: 2019-01
Frequently asked questions
What is Astaxanthin and what is it used for?
Astaxanthin is a potent antioxidant carotenoid currently being studied for potential benefits in inflammation, athletic performance, skin aging, and reproductive health. While research explores these applications, the evidence for most specific health outcomes remains insufficient or weak. It is important to consult a healthcare provider to understand if it is appropriate for your individual health needs.
Does Astaxanthin help with inflammation?
Current research provides weak evidence regarding Astaxanthin's ability to address inflammation. Studies have examined it as part of a combined supplement formula (CEAG) to target endothelial function and inflammation risk, but standalone results are not detailed. Because the evidence is limited, it should not be relied upon as a primary treatment for inflammatory conditions.
Can Astaxanthin improve skin aging?
There is insufficient evidence to confirm that Astaxanthin effectively treats skin aging. Research has investigated its use in combination with lycopene and vitamin E, but specific outcomes are not detailed in the available summaries. One study utilized a dose of 2 mg in combination with other antioxidants, but more robust data is needed to establish efficacy.
Does Astaxanthin help with athletic performance or fatigue?
Research on Astaxanthin's impact on athletic performance and anti-fatigue properties is currently insufficient. Multiple small-scale trials have investigated effects on heart rate during exercise and semen quality, but the results are not detailed in the provided evidence. Consequently, it is unclear if it reliably enhances physical performance.
Is Astaxanthin safe to take with other medications?
No specific drug interactions or contraindications for Astaxanthin were documented in the provided research summaries. However, because safety data is limited, individuals taking other medications should consult a healthcare provider before use. Pregnant or breastfeeding women should also seek medical advice, as safety in these populations has not been established.
What are the side effects of Astaxanthin?
The provided evidence does not detail specific side effects or upper limits for Astaxanthin. While no specific interactions were mentioned, the lack of detailed safety data means potential risks are not fully characterized. Anyone considering supplementation should discuss potential side effects with a healthcare professional.
Who should avoid taking Astaxanthin?
Due to insufficient evidence regarding its safety profile, pregnant or breastfeeding individuals should avoid taking Astaxanthin unless directed by a doctor. Additionally, people with underlying health conditions or those on medication should consult a healthcare provider before use. It is not recommended to replace prescribed medications with this supplement.