Green tea extract is extensively researched for its potential benefits in weight management, cancer prevention, and metabolic health. Overall, research suggests it may influence body composition, lipid profiles, and the risk of certain malignancies, though much of the evidence is based on observational data.

Evidence by Condition

Weight Management Moderate

Evidence suggests green tea may aid in weight loss, weight maintenance, and improvements in body composition.

Cancer Prevention Moderate

Studies indicate potential associations between green tea consumption and reduced risks of breast, pancreatic, and liver cancers.

Cardiometabolic Health Moderate

Research indicates potential benefits for glucose metabolism and the reduction of cardiometabolic risk factors.

Acne Weak

Green tea is evaluated among oral nutraceuticals for acne treatment, but evidence is less definitive.

Effective Doses

Specific dose ranges from RCTs were not explicitly provided in the source text.

Key Findings

Green tea consumption can affect BMI, lipoprotein levels, and liver enzymes (PMID: 36036958).
Green tea consumption is associated with the risk of breast cancer and recurrence (PMID: 30513889).
Green tea extract supplementation impacts body composition, obesity-related hormones, and oxidative stress markers (PMID: 38031409).
Green tea intake is linked to the risk of hepatocellular carcinoma (PMID: 37038314).

Limitations

A significant portion of the evidence for cancer prevention relies on meta-analyses of observational studies, which may be subject to confounding variables.

Safety & Interactions

No specific contraindications or drug interactions were detailed in the provided research summaries.

AI-generated summary from 188 peer-reviewed studies. Not medical advice. Always consult a healthcare provider.

Drug-Supplement Interactions

Antiarrhythmics 🔴 Critical

Mechanism: Green Tea is a weak inhibitor of CYP2C9, which decreases metabolism of CYP2C9 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of amiodarone (antiarrhythmics), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of amiodarone. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Anticonvulsants 🔴 Critical

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of carbamazepine (anticonvulsants), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of carbamazepine. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

GI Prokinetics 🔴 Critical

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of cisapride (gi-prokinetics), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of cisapride. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Immunosuppressants 🔴 Critical

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of cyclosporine (immunosuppressants), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of cyclosporine. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Theophylline 🔴 Critical

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of theophylline (theophylline), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of theophylline. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

ARB 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP2C9, which decreases metabolism of CYP2C9 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of losartan (arb), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of losartan. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Analgesics 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP1A2, which decreases metabolism of CYP1A2 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of acetaminophen (analgesics), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of acetaminophen. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Antibiotics 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of clarithromycin (antibiotics), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of clarithromycin. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Antidiabetic Drugs 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of repaglinide (antidiabetic-drugs), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of repaglinide. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Antifungals 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of fluconazole (antifungals), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of fluconazole. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Antipsychotics 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of haloperidol (antipsychotics), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of haloperidol. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Benzodiazepines 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of midazolam (benzodiazepines), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of midazolam. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Beta Blockers 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP1A2, which decreases metabolism of CYP1A2 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of propranolol (beta-blockers), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of propranolol. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Beta-2 Agonists 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of salmeterol (beta2-agonists), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of salmeterol. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

CFTR Modulators 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of ivacaftor (cftr-modulators), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of ivacaftor. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Caffeine 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP1A2, which decreases metabolism of CYP1A2 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of caffeine (caffeine), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of caffeine. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Calcium Channel Blockers 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of nifedipine (calcium-channel-blockers), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of nifedipine. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Chemotherapy 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of doxorubicin (chemotherapy), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of doxorubicin. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Corticosteroids 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of prednisone (corticosteroids), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of prednisone. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Dopamine Agonists 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP1A2, which decreases metabolism of CYP1A2 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of ropinirole (dopamine-agonists), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of ropinirole. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Leukotriene Antagonists 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of montelukast (leukotriene-antagonists), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of montelukast. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

MAOI 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP1A2, which decreases metabolism of CYP1A2 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of rasagiline (maoi), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of rasagiline. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Melatonin 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP1A2, which decreases metabolism of CYP1A2 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of melatonin (melatonin), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of melatonin. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

NSAIDs 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP2C9, which decreases metabolism of CYP2C9 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of ibuprofen (nsaids), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of ibuprofen. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Opioids 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of methadone (opioids), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of methadone. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Oral Contraceptives 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of ethinylestradiol (oral-contraceptives), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of ethinylestradiol. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

PDE5 Inhibitors 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of sildenafil (pde5-inhibitors), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of sildenafil. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

PPIS 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of omeprazole (ppis), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of omeprazole. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

SNRI 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of venlafaxine (snri), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of venlafaxine. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

SSRI 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of sertraline (ssri), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of sertraline. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Statins 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of simvastatin (statins), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of simvastatin. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Tricyclic Antidepressants 🟡 Moderate

Mechanism: Green Tea is a weak inhibitor of CYP3A4, which decreases metabolism of CYP3A4 substrates, potentially increasing their plasma concentrations and risk of adverse effects.

Effect: Increased plasma levels of amitriptyline (tricyclic-antidepressants), potentially leading to toxicity or enhanced adverse effects.

Management: Monitor for increased adverse effects of amitriptyline. Dose reduction may be necessary. Consider alternative supplement or consult healthcare provider.

Evidence: cyp-inferred

Warfarin 🟡 Moderate

Mechanism: Green tea contains vitamin K which can antagonize warfarin. High consumption may reduce INR.

Effect: Reduced anticoagulant effect at high consumption (>1/2 gallon/day)

Management: Maintain consistent green tea intake. Avoid sudden changes in consumption.

Evidence: well-established

Simvastatin 🟢 Minor

Mechanism: Green tea catechins may inhibit intestinal CYP3A4, potentially increasing simvastatin absorption.

Effect: Possible increased simvastatin levels

Management: Minor clinical concern. Monitor for statin side effects with heavy green tea consumption.

Evidence: possible

⚠️ This information is for educational purposes only and does not constitute medical advice. Always consult your healthcare provider before combining supplements with medications.

Claims vs. Evidence

100% Evidence-Backed

0% Unsupported

86% Structure/Function

Claim Type	% of Products	Evidence Required	Status
All Other	99%	Tier D (Unclassified)	✅ Supported
Structure/Function	86%	Tier C (DSHEA Structure/Function (no pre-approval))	✅ Supported
Nutrient	9%	Tier D (Unknown)	✅ Supported
Qualified Health	0%	Tier B (FDA Qualified Health Claim)	✅ Supported
Approved Health	0%	Tier A (FDA Approved Health Claim (21 CFR 101.9))	✅ Supported
No Claim	0%	Tier D (No claim on label)	✅ Supported

Research by Topic

Green Tea 156 studies

MET The effect of Green green tea consumption on body mass index...

MET Green Tea Consumption and Risk of Breast Cancer and Recurren...

MET Green tea (Camellia sinensis) for the prevention of cancer

+153 more

Dietary Supplement General 11 studies

CLI Pediatric Exploratory Research Study of EGCG Use and Safety ...

CLI Prevention of Cognitive Decline in ApoE4 Carriers With Subje...

CLI Green Tea Supplementation, Fat Oxidation and Body Compositio...

+8 more

Green Tea Metabolic 10 studies

MET Green tea for weight loss and weight maintenance in overweig...

MET The effect of green tea on patients with type 2 diabetes mel...

MET Effects of green tea or green tea extract on insulin sensiti...

+7 more

L Theanine Anxiety 3 studies

MET Effects of Tea (Camellia sinensis) or its Bioactive Compound...

SYS The Effects of Green Tea Amino Acid L-Theanine Consumption o...

RCT Effect of a Combination of Magnesium, B Vitamins, Rhodiola, ...

Rhodiola 1 studies

RCT A combination of green tea, rhodiola, magnesium and B vitami...

L Theanine Focus 1 studies

MET Acute effects of tea constituents L-theanine, caffeine, and ...

L Theanine 1 studies

SYS Green tea effects on cognition, mood and human brain functio...

Resveratrol 1 studies

MET Sulforaphane and Epigallocatechin Gallate Restore Estrogen R...

Alpha Lipoic Acid 1 studies

RCT The Impact of Decaffeinated Green Tea Extract on Fat Oxidati...

Sulforaphane 1 studies

SYS In vitro Biological Effects of Sulforaphane (SFN), Epigalloc...

Curcumin Cancer 1 studies

RCT Chemopreventive Synergism between Green Tea Extract and Curc...

Iron 1 studies

CLI Progression Rate of MSA Under EGCG Supplementation as Anti-A...

⚠️ FDA Safety Data

Adverse Event Profile: Green Tea

Research Evidence (188)

Meta Analysis: 101 Systematic Review: 58 Clinical Trial: 15 Rct: 13 Openfda Safety: 1

A The effect of Green green tea consumption on body mass index, lipoprotein, liver enzymes, and liver cancer: An updated systemic review incorporating a meta-analysis

Meta Analysis Critical reviews in food science and nutrition 2024 n=169599

**Li et al., 2024** | Crit Rev Food Sci Nutr | Meta Analysis Li Mingzhen, Duan Yunjie, ... Yan Jun. The effect of Green green tea consumption on body mass index, lipoprotein, liver enzymes, and liver cancer: An updated systemic review incorporating a...

PubMed DOI

A Green Tea Consumption and Risk of Breast Cancer and Recurrence-A Systematic Review and Meta-Analysis of Observational Studies

Meta Analysis Nutrients 2018 n=163810

**Gianfredi et al., 2018** | Nutrients | Meta Analysis Gianfredi Vincenza, Nucci Daniele, ... Realdon Stefano. Green Tea Consumption and Risk of Breast Cancer and Recurrence-A Systematic Review and Meta-Analysis of Observational Studies. Nutrients. 2...

PubMed DOI

A Green tea (Camellia sinensis) for the prevention of cancer

Meta Analysis The Cochrane database of systematic reviews 2020 n=1795

**Filippini et al., 2020** | Cochrane Database Syst Rev | Meta Analysis Filippini Tommaso, Malavolti Marcella, ... Vinceti Marco. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database Syst Rev. 2020-Mar-02;3(3):CD005004. doi:1...

PubMed DOI

A The Effect of Antioxidant Polyphenol Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis

Meta Analysis Nutrients 2024 n=17126

**Wan et al., 2024** | Nutrients | Meta Analysis Wan Sitong, Luo Junjie, ... Xing Qingchang. The Effect of Antioxidant Polyphenol Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis. Nutrients. 2024-Dec-05;16(23). d...

PubMed DOI

B Green tea for weight loss and weight maintenance in overweight or obese adults

Meta Analysis The Cochrane database of systematic reviews 2012 n=532

BACKGROUND: Preparations of green tea are used as aids in weight loss and weight maintenance. Catechins and caffeine, both contained in green tea, are each believed to have a role in increasing energy metabolism, which may lead to weight loss. A numb...

PubMed DOI Cochrane

B Green tea consumption and risk of pancreatic cancer: a meta-analysis

Meta Analysis Nutrients 2014 n=288209

**Zeng et al., 2014** | Nutrients | Meta Analysis Zeng Jin-Long, Li Zhi-Hua, ... Zhang Hai-Liang. Green tea consumption and risk of pancreatic cancer: a meta-analysis. Nutrients. 2014-Oct-28;6(11):4640-50. doi:10.3390/nu6114640 Emerging laboratory an...

PubMed DOI

B Safety and Effectiveness of Oral Nutraceuticals for Treating Acne: A Systematic Review

Systematic Review JAMA dermatology 2023 n=3346

**Shields et al., 2023** | JAMA Dermatol | Systematic Review Shields Ali, Ly Sophia, ... Barbieri John S. Safety and Effectiveness of Oral Nutraceuticals for Treating Acne: A Systematic Review. JAMA Dermatol. 2023-Dec-01;159(12):1373-1382. doi:10.100...

PubMed DOI

B Dietary Strategies for Weight Loss Maintenance

Meta Analysis Nutrients 2019 n=2875

**van et al., 2019** | Nutrients | Meta Analysis van Baak Marlene A, Mariman Edwin C M. Dietary Strategies for Weight Loss Maintenance. Nutrients. 2019-Aug-15;11(8). doi:10.3390/nu11081916 Weight regain after a successful weight loss intervention is ...

PubMed DOI

B Green and black tea for the primary prevention of cardiovascular disease

Meta Analysis The Cochrane database of systematic reviews 2013 n=821

**Hartley et al., 2013** | Cochrane Database Syst Rev | Meta Analysis Hartley Louise, Flowers Nadine, ... Rees Karen. Green and black tea for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2013-Jun-18;2013(6):CD009934. ...

PubMed DOI

B Risk factors for stomach cancer: a systematic review and meta-analysis

Meta Analysis Epidemiology and health 2020 n=33831063

**Poorolajal et al., 2020** | Epidemiol Health | Meta Analysis Poorolajal Jalal, Moradi Leila, ... Gohari-Ensaf Fatemeh. Risk factors for stomach cancer: a systematic review and meta-analysis. Epidemiol Health. 2020;42:e2020004. doi:10.4178/epih.e202...

PubMed DOI

B The effects of green tea extract supplementation on body composition, obesity-related hormones and oxidative stress markers: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials

Meta Analysis The British journal of nutrition 2024 n=3802

**Asbaghi et al., 2024** | Br J Nutr | Meta Analysis Asbaghi Omid, Rezaei Kelishadi Mahnaz, ... Zamani Mohammad. The effects of green tea extract supplementation on body composition, obesity-related hormones and oxidative stress markers: a grade-asse...

PubMed DOI

B Coffee, Green Tea Intake, and the Risk of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis of Observational Studies

Meta Analysis Nutrition and cancer 2023 n=2492625

**Yu et al., 2023** | Nutr Cancer | Meta Analysis Yu Jinchuan, Liang Di, ... Chen Wenjun. Coffee, Green Tea Intake, and the Risk of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis of Observational Studies. Nutr Cancer. 2023;75(5):1295...

PubMed DOI

B The Implication of Nutrition on the Prevention and Improvement of Age-Related Sarcopenic Obesity: A Systematic Review

Systematic Review The journal of nutrition, health & aging 2023 n=37078

**Abiri et al., 2023** | J Nutr Health Aging | Systematic Review Abiri B, Hosseinpanah F, ... Valizadeh M. The Implication of Nutrition on the Prevention and Improvement of Age-Related Sarcopenic Obesity: A Systematic Review. J Nutr Health Aging. 202...

PubMed DOI

B Green tea and liver cancer risk: A meta-analysis of prospective cohort studies in Asian populations

Meta Analysis Nutrition (Burbank, Los Angeles County, Calif.) 2016 n=465274

**Huang et al., 2016** | Nutrition | Meta Analysis Huang Ya-Qing, Lu Xin, ... Zou Xiao-Ping. Green tea and liver cancer risk: A meta-analysis of prospective cohort studies in Asian populations. Nutrition. 2016-Jan;32(1):3-8. doi:10.1016/j.nut.2015.05...

PubMed DOI

B Effects of Coffee and Tea Consumption on Glucose Metabolism: A Systematic Review and Network Meta-Analysis

Systematic Review Nutrients 2018 n=1898

**Kondo et al., 2018** | Nutrients | Systematic Review Kondo Yoshinobu, Goto Atsushi, ... Noda Mitsuhiko. Effects of Coffee and Tea Consumption on Glucose Metabolism: A Systematic Review and Network Meta-Analysis. Nutrients. 2018-Dec-27;11(1). doi:10...

PubMed DOI

B Preventive effects of tea and tea catechins against influenza and acute upper respiratory tract infections: a systematic review and meta-analysis

Meta Analysis European journal of nutrition 2021 n=3748

**Umeda et al., 2021** | Eur J Nutr | Meta Analysis Umeda Mai, Tominaga Takeichiro, ... Yamada Hiroshi. Preventive effects of tea and tea catechins against influenza and acute upper respiratory tract infections: a systematic review and meta-analysis....

PubMed DOI

B Diet Therapeutics Interventions for Obesity: A Systematic Review and Network Meta-Analysis

Systematic Review Journal of research in health sciences 2021 n=36

**Morsali et al., 2021** | J Res Health Sci | Systematic Review Morsali Mina, Poorolajal Jalal, ... Doosti-Irani Amin. Diet Therapeutics Interventions for Obesity: A Systematic Review and Network Meta-Analysis. J Res Health Sci. 2021-Sep-19;21(3):e00...

PubMed DOI

B Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies

Meta Analysis Nutrition, metabolism, and cardiovascular diseases : NMCD 2023 n=772922

**Wang et al., 2023** | Nutr Metab Cardiovasc Dis | Meta Analysis Wang Ze-Mu, Zhao Di, ... Wang Lian-Sheng. Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies. Nutr Metab Cardiovasc D...

PubMed DOI

B Tea intake or consumption and the risk of dementia: a meta-analysis of prospective cohort studies

Meta Analysis PeerJ 2023 n=410951

**Jiang et al., 2023** | PeerJ | Meta Analysis Jiang Ning, Ma Jinlong, ... Wei Baojian. Tea intake or consumption and the risk of dementia: a meta-analysis of prospective cohort studies. PeerJ. 2023;11:e15688. doi:10.7717/peerj.15688 PURPOSE: Dementi...

PubMed DOI

B Tea consumption, serum uric acid levels and hyperuricemia: a systematic review and meta-analysis

Meta Analysis Clinical rheumatology 2025 n=285221

**Zhu et al., 2025** | Clin Rheumatol | Meta Analysis Zhu Wenhao, Wang Qiwang, ... Lei Yu. Tea consumption, serum uric acid levels and hyperuricemia: a systematic review and meta-analysis. Clin Rheumatol. 2025-Jan;44(1):67-80. doi:10.1007/s10067-024-...

PubMed DOI

B The effect of green tea on patients with type 2 diabetes mellitus: A meta-analysis

Meta Analysis Medicine 2024 n=722

BACKGROUND: To systematically evaluate the effect of green tea on patients with type 2 diabetes. METHODS: A computer search Cochrane, PubMed, Embase, CNKI, Wanfang, VIP, and other Chinese and English databases were conducted for randomized controlled...

PubMed DOI

B Effects of green tea supplementation on antioxidant status and inflammatory markers in adults: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials

Meta Analysis Journal of nutritional science 2025 n=38

**Dehzad et al., 2025** | J Nutr Sci | Meta Analysis Dehzad Mohammad Jafar, Ghalandari Hamid, ... Askarpour Moein. Effects of green tea supplementation on antioxidant status and inflammatory markers in adults: a grade-assessed systematic review and d...

PubMed DOI

B Effect of green tea catechins with or without caffeine on anthropometric measures: a systematic review and meta-analysis

Systematic Review The American journal of clinical nutrition 2010 n=1243

**Phung et al., 2010** | Am J Clin Nutr | Systematic Review Phung Olivia J, Baker William L, ... Coleman Craig I. Effect of green tea catechins with or without caffeine on anthropometric measures: a systematic review and meta-analysis. Am J Clin Nutr...

PubMed DOI

B Effects of Coffee, Black Tea and Green Tea Consumption on the Risk of Non-Hodgkin's Lymphoma: A Systematic Review and Dose-Response Meta-Analysis of Observational Studies

Meta Analysis Nutrition and cancer 2019 n=315972

**Mirtavoos-Mahyari et al., 2019** | Nutr Cancer | Meta Analysis Mirtavoos-Mahyari Hanifeh, Salehipour Pouya, ... Sadeghi Alireza. Effects of Coffee, Black Tea and Green Tea Consumption on the Risk of Non-Hodgkin's Lymphoma: A Systematic Review and D...

PubMed DOI

B Effect of green tea supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Medicine 2020 n=1697

**Xu et al., 2020** | Medicine (Baltimore) | Meta Analysis Xu Renfan, Yang Ke, ... Chen Guangzhi. Effect of green tea supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore). 2020...

PubMed DOI

B Tea consumption and cerebral hemorrhage risk: a meta-analysis

Meta Analysis Acta neurologica Belgica 2022 n=721827

**Cheng et al., 2022** | Acta Neurol Belg | Meta Analysis Cheng Pengfei, Zhang Junxiang, ... Zhu Jiaying. Tea consumption and cerebral hemorrhage risk: a meta-analysis. Acta Neurol Belg. 2022-Oct;122(5):1247-1259. doi:10.1007/s13760-022-01973-6 BACKG...

PubMed DOI

B Effects of green tea on lipid profile in overweight and obese women

Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024 n=1818

**Li et al., 2024** | Int J Vitam Nutr Res | Meta Analysis Li Aixin, Wang Qian, ... Liang Zhaoguang. Effects of green tea on lipid profile in overweight and obese women. Int J Vitam Nutr Res. 2024-Jun;94(3-4):239-251. doi:10.1024/0300-9831/a000783 Th...

PubMed DOI

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B Green tea (Camellia sinensis) for the prevention of cancer

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B Effects of tea intake on blood pressure: a meta-analysis of randomised controlled trials

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B The effects of regular consumption of green or black tea beverage on blood pressure in those with elevated blood pressure or hypertension: A systematic review and meta-analysis

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B Effects of green tea supplementation on obesity indices and adipokines in adults: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials

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Frequently Asked Questions

What is green tea extract and what are its main benefits?

Green tea extract is a supplement derived from tea leaves that is studied for its impact on various health areas. There is moderate evidence suggesting it may support weight management, cancer prevention, and metabolic health.

Can green tea extract help with weight loss?

There is moderate evidence that green tea extract may aid in weight loss, weight maintenance, and improvements in body composition. Research indicates it can influence BMI and obesity-related hormones.

Does green tea extract help prevent cancer?

There is moderate evidence suggesting potential associations between green tea consumption and a reduced risk of certain cancers, including breast, pancreatic, and liver cancers. However, much of this evidence is based on observational data.

Can green tea extract improve metabolic health?

There is moderate evidence that green tea extract may benefit glucose metabolism and reduce cardiometabolic risk factors. It has also been linked to changes in lipoprotein levels.

Is green tea extract effective for treating acne?

There is currently weak evidence regarding the use of green tea extract as an oral treatment for acne. The research in this area is considered less definitive.

What is the recommended dose of green tea extract?

Specific effective dose ranges from clinical trials were not explicitly provided in the available research. You should consult a healthcare provider to determine an appropriate dosage for your needs.

Are there any drug interactions or safety concerns with green tea extract?

No specific drug interactions or contraindications were documented in the reviewed research. However, because research shows it can affect liver enzymes, you should consult a doctor before use.

Who should avoid taking green tea extract?

The provided research does not identify specific groups of people who should avoid this supplement. However, individuals should always consult a medical professional before starting new supplements, especially due to observed effects on liver enzymes.

Answers generated from research evidence. Not medical advice.