Colostrum
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Evidence Summary
Colostrum research focuses on its potential applications in athletic performance, critical care, and neonatal health. Current evidence is primarily derived from clinical trials investigating specific, targeted populations.
Evidence by Condition
Clinical trials have investigated the effects of Bovinum colostrum supplementation in this group.
Research has explored the impact of enteral colostrum on clinical outcomes in intensive care settings.
Studies have evaluated the use of bovine colostrum for preterm infants.
Effective Doses
Not specified in the provided research.
Key Findings
- Clinical trials have investigated the effects of Bovinum colostrum supplementation in endurance athletes (NCT06390670).
- Enteral colostrum has been studied for its impact on clinical outcomes in critically ill patients (NCT03019250).
- Bovine colostrum has been evaluated for use in preterm newborns (NCT03085277).
Limitations
The available research is limited to clinical trials in specific populations, with a lack of large-scale meta-analyses or randomized controlled trials for colostrum.
Safety & Interactions
No specific safety notes or contraindications were provided in the research summaries.
AI-generated summary from 19 peer-reviewed studies. Not medical advice. Always consult a healthcare provider.
Claims vs. Evidence
| Claim Type | % of Products | Evidence Required | Status |
|---|---|---|---|
| All Other | 99% | Tier D (Unclassified) | ✅ Supported |
| Structure/Function | 84% | Tier C (DSHEA Structure/Function (no pre-approval)) | ✅ Supported |
| Nutrient | 26% | Tier D (Unknown) | ✅ Supported |
| No Claim | 1% | Tier D (No claim on label) | ✅ Supported |
Research by Topic
Research Evidence (19)
静脉注射免疫球蛋白（IVIG）具有广谱的抗炎和免疫调节作用，虽已被广泛用于治疗多种儿童神经系统自身免疫性疾病，但在临床中常存在使用不当或过度使用的问题。因此，为指导儿科医师规范使用IVIG治疗儿童神经系统自身免疫性疾病，中华医学会儿科学分会神经学组联合中华儿科杂志编辑委员会组织制订“静脉注射免疫球蛋白在儿童神经系统自身免疫性疾病中的应用专家共识（2025）”，以期指导临床实践。.
The Immunoglobulin A nephropathy (IgAN) and Immunoglobulin A vasculitis (IgAV) management guideline was last updated and published as part of the Kidney Disease: Improving Global Outcomes (KDIGO) 2021 Clinical Practice Guideline for the Management of...
BACKGROUND: Plasma exchange and intravenous immunoglobulin, but not corticosteroids, are beneficial in Guillain-Barré syndrome (GBS). The efficacy of other pharmacological agents is unknown. OBJECTIVES: To review systematically the evidence from rand...
BACKGROUND: Plasma exchange and intravenous immunoglobulin, but not corticosteroids, are beneficial in Guillain-Barré syndrome (GBS). The efficacy of other pharmacological agents is unknown. This review was first published in 2011 and this update in ...
BACKGROUND: Plasma exchange and intravenous immunoglobulin, but not corticosteroids, are beneficial in Guillain-Barré syndrome (GBS). The efficacy of other pharmacological agents is unknown. This review was first published in 2011 and previously upda...
BACKGROUND: Plasma exchange and intravenous immunoglobulin, but not corticosteroids, are beneficial in Guillain-Barré syndrome (GBS). The efficacy of other pharmacological agents is unknown. This review was first published in 2011 and updated in 2013...
**Gajdos et al., 2003** | Cochrane Database Syst Rev | Systematic Review Gajdos P, Chevret S, Toyka K. Intravenous immunoglobulin for myasthenia gravis. Cochrane Database Syst Rev. 2003(2):CD002277 BACKGROUND: Myasthenia gravis is an autoimmune disea...
Essential to human health, selenium (Se) has enzymatic functions of fundamental importance to human biology due to its effects on DNA damage repair, its antioxidant properties, and cancer prevention. The best studied relationships between Se and the ...
**Nazeri et al., 2018** | Thyroid | Meta Analysis Nazeri Pantea, Kabir Ali, ... Azizi Fereidoun. Breast-Milk Iodine Concentrations and Iodine Levels of Infants According to the Iodine Status of the Country of Residence: A Systematic Review and Meta-A...
**Dror et al., 2018** | Adv Nutr | Meta Analysis Dror Daphna K, Allen Lindsay H. Retinol-to-Fat Ratio and Retinol Concentration in Human Milk Show Similar Time Trends and Associations with Maternal Factors at the Population Level: A Systematic Review...
**Dror et al., 2018** | Adv Nutr | Systematic Review Dror Daphna K, Allen Lindsay H. Iodine in Human Milk: A Systematic Review. Adv Nutr. 2018-May-01;9(suppl_1):347S-357S. doi:10.1093/advances/nmy020 Because infants are born with small amounts of sto...
**NCT ID**: NCT05851313 **Phase**: PHASE3 **Status**: COMPLETED **Enrollment**: 500 **Completion**: 2023-04-07
**NCT ID**: NCT06390670 **Phase**: PHASE2 **Status**: COMPLETED **Enrollment**: 58 **Completion**: 2024-03-31
**NCT ID**: NCT03019250 **Phase**: NA **Status**: COMPLETED **Enrollment**: 200 **Completion**: 2018-11-07
**NCT ID**: NCT03085277 **Phase**: NA **Status**: COMPLETED **Enrollment**: 350 **Completion**: 2020-11-18
**NCT ID**: NCT03186716 **Phase**: NA **Status**: COMPLETED **Enrollment**: 70 **Completion**: 2018-03-11
**NCT ID**: NCT03537365 **Phase**: NA **Status**: COMPLETED **Enrollment**: 252 **Completion**: 2022-02-28
**NCT ID**: NCT06123910 **Phase**: NA **Status**: COMPLETED **Enrollment**: 32 **Completion**: 2019-04-05
**NCT ID**: NCT01766804 **Phase**: NA **Status**: COMPLETED **Enrollment**: 62 **Completion**: 2016-12
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Frequently Asked Questions
What is colostrum and what is it used for?
Colostrum is a nutrient-rich substance produced by mammals shortly after birth. Research has investigated its potential applications in athletic performance, critical care, and neonatal health, though there is currently insufficient evidence to support these uses.
Does colostrum help with athletic performance?
There is currently insufficient evidence to determine if colostrum improves performance in endurance athletes. While clinical trials have investigated its effects, more research is needed to confirm any benefits.
Can colostrum be used for critically ill patients?
Research has explored the impact of enteral colostrum on clinical outcomes in intensive care settings, but evidence remains insufficient. More studies are required to understand its impact on this population.
Is bovine colostrum safe for preterm newborns?
Studies have evaluated the use of bovine colostrum for preterm infants, but there is currently insufficient evidence regarding its effectiveness. You should always consult a pediatrician before using supplements for infants.
What is the recommended dose of colostrum?
There is currently no specified effective dose for colostrum supplementation in the available research. Because an optimal dose has not been established, you should consult a healthcare professional for guidance.
Are there any side effects or drug interactions with colostrum?
There are no documented drug interactions or specific safety contraindications provided in the current research. However, because evidence is limited, you should speak with a doctor before starting supplementation.
Who should avoid taking colostrum supplements?
The current research does not identify any specific groups that should avoid colostrum. However, because evidence for its use is insufficient, individuals should consult a medical professional regarding their specific health needs.
Answers generated from research evidence. Not medical advice.