Feverfew
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Evidence Summary
Feverfew is primarily researched for its potential role in migraine prophylaxis and the management of headaches. The body of evidence includes multiple Cochrane reviews and systematic reviews evaluating its efficacy, often in combination with other supplements or therapies.
Evidence by Condition
Research focuses on the use of feverfew for preventing migraine attacks, frequently investigating it in combination with magnesium, riboflavin, or acupuncture.
Effective Doses
Not specified in the provided research.
Key Findings
- Cochrane reviews have provided updated evidence regarding the use of feverfew for preventing migraine (PMID: 25892430).
- A combination of riboflavin, magnesium, and feverfew was studied for migraine prophylaxis (PMID: 15447697).
- The combination of acupuncture and Tanacetum parthenium may improve the quality of life in women with headaches (PMID: 22961605).
- Feverfew has been studied in combination with Salix alba for the prevention of migraines (PMID: 17163262).
Limitations
Many studies involve very small sample sizes (e.g., N=12 or N=22) and often focus on combination therapies rather than feverfew as a monotherapy.
Safety & Interactions
No safety information or drug interactions were provided in the source text.
AI-generated summary from 10 peer-reviewed studies. Not medical advice. Always consult a healthcare provider.
Claims vs. Evidence
| Claim Type | % of Products | Evidence Required | Status |
|---|---|---|---|
| All Other | 99% | Tier D (Unclassified) | ✅ Supported |
| Structure/Function | 67% | Tier C (DSHEA Structure/Function (no pre-approval)) | ✅ Supported |
| Nutrient | 1% | Tier D (Unknown) | ✅ Supported |
| No Claim | 1% | Tier D (No claim on label) | ✅ Supported |
Research by Topic
Research Evidence (10)
BACKGROUND: This review is an update of a previously published review in the Cochrane Database of Systematic Reviews on 'Feverfew for preventing migraine' (2004, Issue 1). Feverfew (Tanacetum parthenium L.) extract is a herbal remedy, which has been ...
**Pittler et al., 2004** | Cochrane Database Syst Rev | Systematic Review Pittler M H, Ernst E. Feverfew for preventing migraine. Cochrane Database Syst Rev. 2004(1):CD002286 BACKGROUND: Feverfew (Tanacetum parthenium L.) extract is a herbal remedy u...
**Pittler et al., 2000** | Cochrane Database Syst Rev | Systematic Review Pittler M H, Vogler B K, Ernst E. Feverfew for preventing migraine. Cochrane Database Syst Rev. 2000(3):CD002286 BACKGROUND: Feverfew (Tanacetum parthenium L.) is a popular her...
**Murphy et al., 1988** | Lancet | Rct Murphy J J, Heptinstall S, Mitchell J R. Randomised double-blind placebo-controlled trial of feverfew in migraine prevention. Lancet. 1988-Jul-23;2(8604):189-92 The use of feverfew (Tanacetum parthenium) for mig...
**Saranitzky et al., 2009** | J Diet Suppl | Systematic Review Saranitzky Elisa, White C Michael, ... Coleman Craig I. Feverfew for migraine prophylaxis: a systematic review. J Diet Suppl. 2009;6(2):91-103. doi:10.1080/19390210902861809 Feverfew has ...
**Shrivastava et al., 2006** | Clin Drug Investig | Meta Analysis Shrivastava R, Pechadre J C, John G W. Tanacetum parthenium and Salix alba (Mig-RL) combination in migraine prophylaxis: a prospective, open-label study. Clin Drug Investig. 2006;26(5)...
**Ferro et al., 2012** | Acupunct Med | Rct Ferro Eliane Cristina, Biagini Angelo Piva, ... Silva Josie Resende Torres. The combined effect of acupuncture and Tanacetum parthenium on quality of life in women with headache: randomised study. Acupunct ...
**Maizels et al., 2004** | Headache | Rct Maizels Morris, Blumenfeld Andrew, Burchette Raoul. A combination of riboflavin, magnesium, and feverfew for migraine prophylaxis: a randomized trial. Headache. 2004-Oct;44(9):885-90 OBJECTIVE: To determine t...
**Vogler et al., 1998** | Cephalalgia | Systematic Review Vogler B K, Pittler M H, Ernst E. Feverfew as a preventive treatment for migraine: a systematic review. Cephalalgia. 1998-Dec;18(10):704-8 BACKGROUND: Feverfew is a popular herbal remedy advoc...
**Johnson et al., 1985** | Br Med J (Clin Res Ed) | Rct Johnson E S, Kadam N P, ... Hylands P J. Efficacy of feverfew as prophylactic treatment of migraine. Br Med J (Clin Res Ed). 1985-Aug-31;291(6495):569-73 Seventeen patients who ate fresh leaves ...
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Frequently Asked Questions
What is feverfew and what is it used for?
Feverfew is a supplement primarily researched for its potential role in preventing migraine attacks and managing headaches. There is moderate evidence regarding its use for migraine prophylaxis.
Does feverfew help with migraines?
There is moderate evidence suggesting that feverfew may help prevent migraine attacks. Research often investigates its effectiveness when used in combination with other therapies like magnesium, riboflavin, or acupuncture.
What is the effective dose of feverfew for migraines?
The provided research does not specify an effective dose for feverfew. You should consult a healthcare professional for personalized dosing recommendations.
Are there any known drug interactions with feverfew?
No specific drug interactions have been documented in the available research. However, you should always consult a doctor before combining supplements with any prescription medications.
Is feverfew safe to take?
The provided research does not include specific safety information or known side effects for feverfew. It is important to speak with a medical professional to ensure any new supplement is safe for your specific health needs.
Can feverfew be taken with other supplements?
Some studies have explored using feverfew in combination with magnesium, riboflavin, or Salix alba for migraine prevention. You should discuss any combination of supplements with a healthcare provider.
Who should avoid taking feverfew?
The provided research does not specify which populations should avoid feverfew. Because safety and interaction data are limited, you should consult a doctor to determine if it is appropriate for you.
Answers generated from research evidence. Not medical advice.