Holy Basil
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Evidence Summary
Research on basil (specifically Ocimum basilicum) suggests potential benefits for alleviating anxiety in patients with major depressive disorder and modulating the body's stress response. Current evidence is limited to a very small number of recent randomized controlled trials.
Evidence by Condition
Ocimum basilicum may help alleviate anxiety symptoms in patients diagnosed with MDD.
Multi-herb formulas containing basil may assist in modulating the HPA axis and managing chronic stress.
Effective Doses
Dose ranges are not specified in the provided research.
Key Findings
- Ocimum basilicum may alleviate anxiety in patients with Major Depressive Disorder (PMID: 41236933)
- Multi-herb and ashwagandha formulas may assist in stress modulation (PMID: 41656269)
Limitations
The current body of evidence is extremely limited, consisting of only two recent randomized controlled trials.
Safety & Interactions
No specific interactions or contraindications were mentioned in the provided studies.
AI-generated summary from 2 peer-reviewed studies. Not medical advice. Always consult a healthcare provider.
Claims vs. Evidence
| Claim Type | % of Products | Evidence Required | Status |
|---|---|---|---|
| All Other | 99% | Tier D (Unclassified) | ✅ Supported |
| Structure/Function | 92% | Tier C (DSHEA Structure/Function (no pre-approval)) | ✅ Supported |
| No Claim | 0% | Tier D (No claim on label) | ✅ Supported |
| Nutrient | 0% | Tier D (Unknown) | ✅ Supported |
Research by Topic
Research Evidence (2)
**Talaei et al., 2025** | Brain Behav | Rct Talaei Mahva, Zare Kiarash, ... Mosavat Sayed Hamdollah. Basil (Ocimum basilicum) to Alleviate Anxiety in Patients With Major Depressive Disorder: A Randomized Placebo-Controlled Clinical Trial. Brain Behav...
BACKGROUND: Chronic stress is detrimental to the maintenance of the main response system - the hypothalamic-pituitary-adrenal (HPA) axis. The current study aimed to investigate the efficacy of two plant-based adaptogens, a formula containing Rhodiola...
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Frequently Asked Questions
What is Holy Basil and what is it used for?
Holy Basil (Ocimum basilicum) is an herb that may help manage the body's stress response. There is currently weak evidence regarding its specific health benefits.
Can Holy Basil help with anxiety?
There is weak evidence suggesting that Holy Basil may help alleviate anxiety symptoms in individuals diagnosed with major depressive disorder. However, more research is needed to confirm these findings.
Does Holy Basil help with stress management?
There is weak evidence that multi-herb formulas containing basil may assist in managing chronic stress by modulating the HPA axis. Most current research focuses on basil as part of a larger herbal blend rather than alone.
What is the effective dose of Holy Basil?
Current research does not specify an effective or recommended dose range for Holy Basil. You should consult a healthcare professional for personalized dosing advice.
Is Holy Basil safe to take?
No specific safety concerns or contraindications have been identified in the available studies. However, because the evidence is limited, you should consult a doctor before starting use.
Are there any drug interactions with Holy Basil?
There are currently no documented drug interactions for Holy Basil. You should always inform your physician about any supplements you are taking to ensure they are safe for your specific health needs.
Who should avoid taking Holy Basil?
The provided research does not identify any specific groups of people who should avoid Holy Basil. However, individuals with underlying health conditions should consult a medical professional before use.
Answers generated from research evidence. Not medical advice.