Passionflower
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Evidence Summary
Passionflower is a herbal supplement primarily researched for its potential anxiolytic and sedative properties. Overall research, including a meta-analysis, suggests it may be effective in reducing anxiety and improving sleep quality.
Evidence by Condition
Research indicates effectiveness in treating generalized anxiety and managing acute anxiety during dental procedures.
Studies show improvements in both subjective sleep quality and polysomnographic sleep parameters.
Effective Doses
Dose ranges are not explicitly provided in the provided research snippets.
Key Findings
- A meta-analysis supports the use of Passiflora for anxiety disorder (PMID: 17253512).
- Passiflora herbal tea has been shown to improve subjective sleep quality (PMID: 21294203).
- Passiflora is effective in controlling anxiety during tooth extraction, sometimes in combination with Valeriana officinalis (PMID: 38743126).
- The supplement may improve polysomnographic sleep parameters in subjects with insomnia disorder (PMID: 31714321).
Limitations
Much of the evidence focuses on acute anxiety related to dental extractions or small-scale trials, with a need for more broad-spectrum long-term studies.
Safety & Interactions
No specific interactions or contraindications were mentioned in the provided research text.
AI-generated summary from 7 peer-reviewed studies. Not medical advice. Always consult a healthcare provider.
Claims vs. Evidence
| Claim Type | % of Products | Evidence Required | Status |
|---|---|---|---|
| All Other | 99% | Tier D (Unclassified) | ✅ Supported |
| Structure/Function | 90% | Tier C (DSHEA Structure/Function (no pre-approval)) | ✅ Supported |
| No Claim | 1% | Tier D (No claim on label) | ✅ Supported |
| Nutrient | 1% | Tier D (Unknown) | ✅ Supported |
Research by Topic
Research Evidence (7)
**Miyasaka et al., 2007** | Cochrane Database Syst Rev | Meta Analysis Miyasaka L S, Atallah A N, Soares B G O. Passiflora for anxiety disorder. Cochrane Database Syst Rev. 2007-Jan-24(1):CD004518 BACKGROUND: Anxiety is a very common mental health pr...
**Lee et al., 2020** | Int Clin Psychopharmacol | Rct Lee Jeewon, Jung Han-Young, ... Kim Shin-Gyeom. Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-...
**Velasquez et al., 2024** | Oral Maxillofac Surg | Rct Velasquez Amalia Celsy Abregu, Tsuji Mayumi, ... Scariot Rafaela. Effects of Passiflora incarnata and Valeriana officinalis in the control of anxiety due to tooth extraction: a randomized contro...
**Ngan et al., 2011** | Phytother Res | Rct Ngan A, Conduit R. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011-Aug;25(8):1153-9. doi:1...
**Dantas et al., 2017** | Med Oral Patol Oral Cir Bucal | Rct Dantas L-P, de Oliveira-Ribeiro A, ... Groppo F-C. Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction. Med Oral Patol Oral Cir Bu...
BACKGROUND: Global lifetime prevalence of anxiety disorders has been estimated at approximately 16.6%, with subclinical prevalence likely much higher. Herbal approaches to reduce anxiety may be as effective as pharmacological treatments and are less ...
**Akhondzadeh et al., 2001** | J Clin Pharm Ther | Rct Akhondzadeh S, Naghavi H R, ... Khani M. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. J Clin Pharm Ther. 2001-Oct;26(5):3...
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Frequently Asked Questions
What is passionflower and what is it used for?
Passionflower is a herbal supplement primarily used for its potential sedative and anxiety-reducing properties. There is moderate evidence suggesting it can help manage anxiety and improve sleep quality.
Does passionflower help with anxiety?
Yes, there is moderate evidence that passionflower is effective for treating generalized anxiety and managing acute anxiety, such as during dental procedures. It may also be effective when used in combination with Valerian.
Can passionflower help with insomnia or sleep?
There is moderate evidence that passionflower can improve both subjective sleep quality and specific sleep parameters in individuals with insomnia. Specifically, passionflower tea has been shown to help improve how people experience their sleep.
What is the recommended dose of passionflower?
Current research does not provide specific effective dose ranges for passionflower. You should consult with a healthcare professional to determine the appropriate amount for your needs.
Are there any safety concerns or side effects with passionflower?
The provided research does not mention any specific safety concerns or contraindications for passionflower. However, you should always consult a doctor before starting a new supplement.
Does passionflower interact with any medications?
There are no documented drug interactions for passionflower in the available research. However, it is important to speak with your physician to ensure it will not interfere with any current treatments.
Who should avoid taking passionflower?
The current research does not identify any specific groups of people who should avoid passionflower. As with any herbal supplement, individuals should consult a medical professional regarding their specific health status.
Answers generated from research evidence. Not medical advice.