Resveratrol is a polyphenol with extensive research investigating its impact on various metabolic and inflammatory markers. Meta-analyses suggest potential benefits for managing non-communicable disease risk factors, including blood pressure, lipids, and glucose metabolism.

Evidence by Condition

Type 2 Diabetes Mellitus Moderate

Meta-analyses indicate that resveratrol supplementation can affect metabolic indicators and glucose management.

Non-Alcoholic Fatty Liver Disease (NAFLD) Moderate

Evidence suggests efficacy in improving liver enzymes and overall disease status in patients.

Inflammation Moderate

Meta-analysis of randomized clinical trials shows that resveratrol can change inflammatory mediators.

Blood Pressure Moderate

Meta-analysis of randomized controlled trials demonstrates an effect on blood pressure regulation.

Weight Loss Weak

Meta-analysis of randomized controlled trials suggests potential effects on weight loss.

Bone Health Moderate

Systematic reviews and meta-analyses show effects on bone biomarkers.

Blood Lipid Profile Moderate

Dose-response meta-analyses indicate an effect on blood lipid profiles.

Effective Doses

Specific dose ranges were not explicitly detailed in the provided research summaries, though dose-response meta-analyses have been conducted.

Key Findings

Resveratrol supplementation affects metabolic indicators in patients with Type 2 Diabetes (PMID: 35685602).
Resveratrol supplementation can change inflammatory mediators (PMID: 30013206).
Efficacy is noted in improving liver enzymes in patients with NAFLD (PMID: 33271299).
Resveratrol has a dose-response effect on blood lipid profiles (PMID: 36145131).

Limitations

There are significant gaps and opportunities in current clinical trials regarding the long-term management of human health with resveratrol (PMID: 38255828).

Safety & Interactions

No specific interactions or contraindications were provided in the research summaries.

AI-generated summary from 193 peer-reviewed studies. Not medical advice. Always consult a healthcare provider.

Claims vs. Evidence

80% Evidence-Backed

20% Unsupported

92% Structure/Function

Claim Type	% of Products	Evidence Required	Status
All Other	99%	Tier D (Unclassified)	✅ Supported
Structure/Function	92%	Tier C (DSHEA Structure/Function (no pre-approval))	✅ Supported
Nutrient	8%	Tier D (Unknown)	✅ Supported
No Claim	0%	Tier D (No claim on label)	✅ Supported
Approved Health	0%	Tier A (FDA Approved Health Claim (21 CFR 101.9))	⚠️ Unsupported

🏛️ NIH ODS Factsheet

Resveratrol

Research by Topic

Resveratrol 177 studies

MET Effects of resveratrol supplementation on risk factors of no...

SYS Resveratrol for the Management of Human Health: How Far Have...

SYS Endocrine disrupting chemicals and breast cancer: a systemat...

+174 more

Curcumin 3 studies

MET Efficacy and safety of dietary polyphenols in rheumatoid art...

SYS Effects of Resveratrol, Curcumin and Quercetin Supplementati...

SYS Impact of curcumin, quercetin, or resveratrol on the pathoph...

Dietary Supplement General 3 studies

CLI Combined Rehabilitation With ALA, ALC, Resveratrol and Vitam...

CLI Evaluating the Clinical Efficacy of Resveratrol in Improving...

CLI The Effects of Resveratrol Supplement on Biochemical Factors...

Cochrane Specialty 1 studies

MET Resveratrol for adults with type 2 diabetes mellitus

Iron 1 studies

SYS Foetal haemoglobin inducers for reducing blood transfusion i...

Vitamin C Exercise 1 studies

RCT The Administration of Resveratrol and Vitamin C Reduces Oxid...

Berberine 1 studies

SYS Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and B...

Creatine 1 studies

SYS Systematic review and meta-analysis of the interventional ef...

Quercetin 1 studies

SYS Investigating the impact of resveratrol and quercetin on gly...

Omega 3 1 studies

SYS The effect of two anti-inflammatory dietary components, omeg...

Cochrane Curcumin Inflammation 1 studies

RCT Effects of Mediterranean Diet, Curcumin, and Resveratrol on ...

Carnitine 1 studies

RCT No effect of resveratrol on fatty acid oxidation or exercise...

Magnesium 1 studies

CLI Resveratrol for the Treatment of Non Alcoholic Fatty Liver D...

⚠️ FDA Safety Data

Adverse Event Profile: Resveratrol

Research Evidence (193)

Systematic Review: 92 Meta Analysis: 83 Rct: 9 Clinical Trial: 7 Openfda Safety: 1

B Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials

Meta Analysis Critical reviews in food science and nutrition 2018 n=1069

**Guo et al., 2018** | Crit Rev Food Sci Nutr | Meta Analysis Guo Xiao-Fei, Li Jiao-Mei, ... Li Duo. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials. Crit Rev Food S...

PubMed DOI

B Resveratrol for adults with type 2 diabetes mellitus

Meta Analysis The Cochrane database of systematic reviews 2020 n=50

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic disorder that is characterised by insulin resistance and hyperglycaemia, which over time may give rise to vascular complications. Resveratrol is a plant-derived nutritional supplement shown to ...

PubMed DOI Cochrane

B Resveratrol for the Management of Human Health: How Far Have We Come? A Systematic Review of Resveratrol Clinical Trials to Highlight Gaps and Opportunities

Systematic Review International journal of molecular sciences 2024 n=200

**Brown et al., 2024** | Int J Mol Sci | Systematic Review Brown Karen, Theofanous Despoina, ... Howells Lynne. Resveratrol for the Management of Human Health: How Far Have We Come? A Systematic Review of Resveratrol Clinical Trials to Highlight Gaps...

PubMed DOI

B Endocrine disrupting chemicals and breast cancer: a systematic review of epidemiological studies

Systematic Review Critical reviews in food science and nutrition 2022 n=131

**Wan et al., 2022** | Crit Rev Food Sci Nutr | Systematic Review Wan Murphy Lam Yim, Co Vanessa Anna, El-Nezami Hani. Endocrine disrupting chemicals and breast cancer: a systematic review of epidemiological studies. Crit Rev Food Sci Nutr. 2022;62(2...

PubMed DOI

B Can resveratrol supplement change inflammatory mediators? A systematic review and meta-analysis on randomized clinical trials

Meta Analysis European journal of clinical nutrition 2019 n=658

**Haghighatdoost et al., 2019** | Eur J Clin Nutr | Meta Analysis Haghighatdoost Fahimeh, Hariri Mitra. Can resveratrol supplement change inflammatory mediators? A systematic review and meta-analysis on randomized clinical trials. Eur J Clin Nutr. 20...

PubMed DOI

B Effects of resveratrol supplementation on bone biomarkers: a systematic review and meta-analysis

Meta Analysis Annals of the New York Academy of Sciences 2019 n=264

**Asis et al., 2019** | Ann N Y Acad Sci | Meta Analysis Asis Marzieh, Hemmati Niloufar, ... Bishayee Anupam. Effects of resveratrol supplementation on bone biomarkers: a systematic review and meta-analysis. Ann N Y Acad Sci. 2019-Dec;1457(1):92-103....

PubMed DOI

B The effects of resveratrol intake on weight loss: a systematic review and meta-analysis of randomized controlled trials

Meta Analysis Critical reviews in food science and nutrition 2020 n=36

**Tabrizi et al., 2020** | Crit Rev Food Sci Nutr | Meta Analysis Tabrizi Reza, Tamtaji Omid Reza, ... Asemi Zatollah. The effects of resveratrol intake on weight loss: a systematic review and meta-analysis of randomized controlled trials. Crit Rev F...

PubMed DOI

B Resveratrol supplementation and type 2 diabetes: a systematic review and meta-analysis

Meta Analysis Critical reviews in food science and nutrition 2022

**Delpino et al., 2022** | Crit Rev Food Sci Nutr | Meta Analysis Delpino Felipe Mendes, Figueiredo Lílian Munhoz. Resveratrol supplementation and type 2 diabetes: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2022;62(16):4465-4480. ...

PubMed DOI

B Effect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2015 n=247

**Liu et al., 2015** | Clin Nutr | Meta Analysis Liu Yanxia, Ma Wanqiang, ... Huang Daifa. Effect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials. Clin Nutr. 2015-Feb;34(1):27-34. doi:10.1016/j.clnu.2014.03.009 BACKG...

PubMed DOI

B Effects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease-A Meta-Analysis

Meta Analysis Nutrients 2020 n=302

**Jakubczyk et al., 2020** | Nutrients | Meta Analysis Jakubczyk Karolina, Skonieczna-Żydecka Karolina, ... Janda Katarzyna. Effects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease-A Meta-Analysis. Nutrients. 2020-Au...

PubMed DOI

B Efficacy of resveratrol supplementation on liver enzymes in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis

Meta Analysis Complementary therapies in medicine 2021 n=216

**Wei et al., 2021** | Complement Ther Med | Meta Analysis Wei Shumin, Yu Xiaoying. Efficacy of resveratrol supplementation on liver enzymes in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis. Complement Ther Me...

PubMed DOI

B Foetal haemoglobin inducers for reducing blood transfusion in non-transfusion-dependent beta-thalassaemias

Systematic Review The Cochrane database of systematic reviews 2023 n=291

**Foong et al., 2023** | Cochrane Database Syst Rev | Systematic Review Foong Wai Cheng, Loh C Khai, ... Lau Doris Sc. Foetal haemoglobin inducers for reducing blood transfusion in non-transfusion-dependent beta-thalassaemias. Cochrane Database Syst ...

PubMed DOI

B The effect of dietary (poly)phenols on exercise-induced physiological adaptations: A systematic review and meta-analysis of human intervention trials

Meta Analysis Critical reviews in food science and nutrition 2022 n=22

**Martinez-Negrin et al., 2022** | Crit Rev Food Sci Nutr | Meta Analysis Martinez-Negrin Guille, Acton Jarred P, ... Clifford Tom. The effect of dietary (poly)phenols on exercise-induced physiological adaptations: A systematic review and meta-analys...

PubMed DOI

B Effects of Resveratrol on Metabolic Indicators in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

Meta Analysis International journal of clinical practice 2022 n=1151

**Gu et al., 2022** | Int J Clin Pract | Meta Analysis Gu Wei, Geng Jianlin, ... Song Guangyao. Effects of Resveratrol on Metabolic Indicators in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis. Int J Clin Pract. 2022;2022:973473...

PubMed DOI

B The Effect of Resveratrol on Blood Lipid Profile: A Dose-Response Meta-Analysis of Randomized Controlled Trials

Meta Analysis Nutrients 2022

**Cao et al., 2022** | Nutrients | Meta Analysis Cao Xinyi, Liao Wang, ... Sun Guiju. The Effect of Resveratrol on Blood Lipid Profile: A Dose-Response Meta-Analysis of Randomized Controlled Trials. Nutrients. 2022-Sep-11;14(18). doi:10.3390/nu141837...

PubMed DOI

B Therapeutic Potential of Resveratrol for Glioma: A Systematic Review and Meta-Analysis of Animal Model Studies

Meta Analysis International journal of molecular sciences 2023

**Luís et al., 2023** | Int J Mol Sci | Meta Analysis Luís Ângelo, Marcelino Helena, ... Cascalheira José Francisco. Therapeutic Potential of Resveratrol for Glioma: A Systematic Review and Meta-Analysis of Animal Model Studies. Int J Mol Sci. 2023-N...

PubMed DOI

B The effect of resveratrol supplementation on C-reactive protein (CRP) in type 2 diabetic patients: Results from a systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2020 n=491

**Hosseini et al., 2020** | Complement Ther Med | Meta Analysis Hosseini Hossein, Koushki Mehdi, ... Meshkani Reza. The effect of resveratrol supplementation on C-reactive protein (CRP) in type 2 diabetic patients: Results from a systematic review an...

PubMed DOI

B Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials

Meta Analysis BMC complementary medicine and therapies 2021 n=698

**Li et al., 2021** | BMC Complement Med Ther | Meta Analysis Li Qiangqiang, Yang Guangpu, ... Lee Wayne Yuk-Wai. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Compl...

PubMed DOI

B Evaluating the Therapeutic Properties of Natural Products in Orthodontic and Surgical Treatment of Dentofacial Deformities: A Systematic Review of Clinical Trials

Systematic Review Nutrients 2024 n=358

**Talpos et al., 2024** | Nutrients | Systematic Review Talpos Niculescu Serban, Avramut Robert, ... Popa Malina. Evaluating the Therapeutic Properties of Natural Products in Orthodontic and Surgical Treatment of Dentofacial Deformities: A Systematic...

PubMed DOI

B Effect of resveratrol on blood pressure: A systematic review and meta-analysis of randomized, controlled, clinical trials

Meta Analysis Critical reviews in food science and nutrition 2019 n=17

**Fogacci et al., 2019** | Crit Rev Food Sci Nutr | Meta Analysis Fogacci Federica, Tocci Giuliano, ... Cicero Arrigo F G. Effect of resveratrol on blood pressure: A systematic review and meta-analysis of randomized, controlled, clinical trials. Crit...

PubMed DOI

B Targeting Mammalian 5-Lipoxygenase by Dietary Phenolics as an Anti-Inflammatory Mechanism: A Systematic Review

Systematic Review International journal of molecular sciences 2021

**Giménez-Bastida et al., 2021** | Int J Mol Sci | Systematic Review Giménez-Bastida Juan Antonio, González-Sarrías Antonio, ... Espín Juan Carlos. Targeting Mammalian 5-Lipoxygenase by Dietary Phenolics as an Anti-Inflammatory Mechanism: A Systemati...

PubMed DOI

B Benefits and Implications of Resveratrol Supplementation on Microbiota Modulations: A Systematic Review of the Literature

Systematic Review International journal of molecular sciences 2022

**Inchingolo et al., 2022** | Int J Mol Sci | Systematic Review Inchingolo Alessio Danilo, Malcangi Giuseppina, ... Dipalma Gianna. Benefits and Implications of Resveratrol Supplementation on Microbiota Modulations: A Systematic Review of the Literat...

PubMed DOI

B Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials

Meta Analysis Frontiers in immunology 2023 n=3852

**Long et al., 2023** | Front Immunol | Meta Analysis Long Zhiyong, Xiang Wang, ... Huang Zhen. Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials. Front Immuno...

PubMed DOI

B Exploitation of Autophagy Inducers in the Management of Dementia: A Systematic Review

Systematic Review International journal of molecular sciences 2024

**Corasaniti et al., 2024** | Int J Mol Sci | Systematic Review Corasaniti Maria Tiziana, Bagetta Giacinto, ... Scuteri Damiana. Exploitation of Autophagy Inducers in the Management of Dementia: A Systematic Review. Int J Mol Sci. 2024-Jan-19;25(2). ...

PubMed DOI

B The efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind placebo meta-analysis

Meta Analysis Frontiers in endocrinology 2024 n=533

**Zhu et al., 2024** | Front Endocrinol (Lausanne) | Meta Analysis Zhu Peiye, Jin Yunrui, ... Zhou Xia. The efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind pla...

PubMed DOI

B A Systematic Review on the Molecular Mechanisms of Resveratrol in Protecting Against Osteoporosis

Systematic Review International journal of molecular sciences 2025 n=28

**Shuid et al., 2025** | Int J Mol Sci | Systematic Review Shuid Ahmad Nazrun, Abdul Nasir Nurul Alimah, ... Naina Mohamed Isa. A Systematic Review on the Molecular Mechanisms of Resveratrol in Protecting Against Osteoporosis. Int J Mol Sci. 2025-Mar...

PubMed DOI

B Effects of resveratrol supplementation on plasma lipids: a systematic review and meta-analysis of randomized controlled trials

Meta Analysis Nutrition reviews 2013 n=282

**Sahebkar et al., 2013** | Nutr Rev | Meta Analysis Sahebkar Amirhossein. Effects of resveratrol supplementation on plasma lipids: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev. 2013-Dec;71(12):822-35. doi:10.1111/n...

PubMed DOI

B What is the effect of resveratrol on obesity? A systematic review and meta-analysis

Meta Analysis Clinical nutrition ESPEN 2021

**Delpino et al., 2021** | Clin Nutr ESPEN | Meta Analysis Delpino Felipe Mendes, Figueiredo Lílian Munhoz, ... Gigante Denise Petrucci. What is the effect of resveratrol on obesity? A systematic review and meta-analysis. Clin Nutr ESPEN. 2021-Feb;41...

PubMed DOI

B Resveratrol and Markers of Polycystic Ovary Syndrome: a Systematic Review of Animal and Clinical Studies

Systematic Review Reproductive sciences (Thousand Oaks, Calif.) 2022

**Shojaei-Zarghani et al., 2022** | Reprod Sci | Systematic Review Shojaei-Zarghani Sara, Rafraf Maryam. Resveratrol and Markers of Polycystic Ovary Syndrome: a Systematic Review of Animal and Clinical Studies. Reprod Sci. 2022-Sep;29(9):2477-2487. d...

PubMed DOI

B The effects of resveratrol supplementation in patients with type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease: an umbrella review of meta-analyses of randomized controlled trials

Meta Analysis The American journal of clinical nutrition 2021 n=6

**Zeraattalab-Motlagh et al., 2021** | Am J Clin Nutr | Meta Analysis Zeraattalab-Motlagh Sheida, Jayedi Ahmad, Shab-Bidar Sakineh. The effects of resveratrol supplementation in patients with type 2 diabetes, metabolic syndrome, and nonalcoholic fatt...

PubMed DOI

B Endometriosis and Phytoestrogens: Friends or Foes? A Systematic Review

Systematic Review Nutrients 2021 n=60

**Bartiromo et al., 2021** | Nutrients | Systematic Review Bartiromo Ludovica, Schimberni Matteo, ... Candiani Massimo. Endometriosis and Phytoestrogens: Friends or Foes? A Systematic Review. Nutrients. 2021-Jul-24;13(8). doi:10.3390/nu13082532 The a...

PubMed DOI

B Effects of Resveratrol Supplementation on the Cognitive Function of Patients with Alzheimer's Disease: A Systematic Review of Randomized Controlled Trials

Systematic Review Drugs & aging 2022 n=1855

**Tosatti et al., 2022** | Drugs Aging | Systematic Review Tosatti Jéssica Abdo Gonçalves, Fontes Adriana Fialho da Silva, ... Gomes Karina Braga. Effects of Resveratrol Supplementation on the Cognitive Function of Patients with Alzheimer's Disease: ...

PubMed DOI

B Resveratrol's bibliometric and visual analysis from 2014 to 2023

Systematic Review Frontiers in plant science 2024

**Wei et al., 2024** | Front Plant Sci | Systematic Review Wei Haoyue, Fang Guowei, ... Huang Yanqin. Resveratrol's bibliometric and visual analysis from 2014 to 2023. Front Plant Sci. 2024;15:1423323. doi:10.3389/fpls.2024.1423323 INTRODUCTION: Resv...

PubMed DOI

B Resveratrol and Female Fertility: A Systematic Review

Systematic Review International journal of molecular sciences 2024

**Bertoldo et al., 2024** | Int J Mol Sci | Systematic Review Bertoldo Alessandro, Pizzol Damiano, ... Smith Lee. Resveratrol and Female Fertility: A Systematic Review. Int J Mol Sci. 2024-Nov-28;25(23). doi:10.3390/ijms252312792 Resveratrol is a nat...

PubMed DOI

B Effects of resveratrol supplementation on renal function in adults: a systematic review and dose-response meta-analysis

Meta Analysis Naunyn-Schmiedeberg's archives of pharmacology 2025 n=2299

**Hajhashemy et al., 2025** | Naunyn Schmiedebergs Arch Pharmacol | Meta Analysis Hajhashemy Zahra, Ziaei Rahele, ... Sahebkar Amirhossein. Effects of resveratrol supplementation on renal function in adults: a systematic review and dose-response meta...

PubMed DOI

B Effect of Resveratrol Supplementation on Inflammatory Markers: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Meta Analysis Clinical therapeutics 2018 n=736

**Koushki et al., 2018** | Clin Ther | Meta Analysis Koushki Mehdi, Dashatan Nasrin Amiri, Meshkani Reza. Effect of Resveratrol Supplementation on Inflammatory Markers: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Clin Ther....

PubMed DOI

B Metabolic and neurological consequences of the treatment with polyphenols: a systematic review in rodent models of noncommunicable diseases

Systematic Review Nutritional neuroscience 2022

**Lacerda et al., 2022** | Nutr Neurosci | Systematic Review Lacerda D C, Urquiza-Martínez M V, ... Guzmán-Quevedo O. Metabolic and neurological consequences of the treatment with polyphenols: a systematic review in rodent models of noncommunicable d...

PubMed DOI

B Can grape polyphenols affect glycation markers? A systematic review

Systematic Review Critical reviews in food science and nutrition 2023

**Coelho et al., 2023** | Crit Rev Food Sci Nutr | Systematic Review Coelho Olívia G L, Ribeiro Priscila V M, Alfenas Rita de Cássia G. Can grape polyphenols affect glycation markers? A systematic review. Crit Rev Food Sci Nutr. 2023;63(9):1208-1218....

PubMed DOI

B Effect of nutritional supports on malnutrition, cognition, function and biomarkers of Alzheimer's disease: a systematic review

Systematic Review The International journal of neuroscience 2023

**Kocatürk et al., 2023** | Int J Neurosci | Systematic Review Kocatürk Rümeysa Rabia, Temizyürek Arzu, ... Tarhan Nevzat. Effect of nutritional supports on malnutrition, cognition, function and biomarkers of Alzheimer's disease: a systematic review....

PubMed DOI

B Effects of Resveratrol, Curcumin and Quercetin Supplementation on Bone Metabolism-A Systematic Review

Systematic Review Nutrients 2022

**Inchingolo et al., 2022** | Nutrients | Systematic Review Inchingolo Alessio Danilo, Inchingolo Angelo Michele, ... Dipalma Gianna. Effects of Resveratrol, Curcumin and Quercetin Supplementation on Bone Metabolism-A Systematic Review. Nutrients. 20...

PubMed DOI

B Potential of Polyphenols for Improving Sleep: A Preliminary Results from Review of Human Clinical Trials and Mechanistic Insights

Meta Analysis Nutrients 2023

**Hibi et al., 2023** | Nutrients | Meta Analysis Hibi Masanobu. Potential of Polyphenols for Improving Sleep: A Preliminary Results from Review of Human Clinical Trials and Mechanistic Insights. Nutrients. 2023-Mar-02;15(5). doi:10.3390/nu15051257 G...

PubMed DOI

B Resveratrol as an Anti-inflammatory Agent in Coronary Artery Disease: A Systematic Review, Meta-Analysis and Meta-Regression

Meta Analysis Chinese journal of integrative medicine 2024

**Damay et al., 2024** | Chin J Integr Med | Meta Analysis Damay Vito A, Ivan Ignatius. Resveratrol as an Anti-inflammatory Agent in Coronary Artery Disease: A Systematic Review, Meta-Analysis and Meta-Regression. Chin J Integr Med. 2024-Oct;30(10):9...

PubMed DOI

B A Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Impact of Resveratrol Supplementation on Anthropometric Indices in Patients With Type 2 Diabetes

Meta Analysis Phytotherapy research : PTR 2025 n=614

**Lahouti et al., 2025** | Phytother Res | Meta Analysis Lahouti Maryam, Arzhang Pishva, Azadbakht Leila. A Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Impact of Resveratrol Supplementation on Anthropometric Indices in ...

PubMed DOI

B Does phytoestrogen supplementation improve cognition in humans? A systematic review

Systematic Review Annals of the New York Academy of Sciences 2017 n=23

**Thaung et al., 2017** | Ann N Y Acad Sci | Systematic Review Thaung Zaw Jay Jay, Howe Peter Ranald Charles, Wong Rachel Heloise Xiwen. Does phytoestrogen supplementation improve cognition in humans? A systematic review. Ann N Y Acad Sci. 2017-Sep;1...

PubMed DOI

B Effect of Resveratrol on Blood Lipid Levels in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

Meta Analysis Obesity (Silver Spring, Md.) 2019 n=363

**Zhao et al., 2019** | Obesity (Silver Spring) | Meta Analysis Zhao Hang, Song An, ... Ma Huijuan. Effect of Resveratrol on Blood Lipid Levels in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis. Obesity (Silver Spring). 2019-Jan...

PubMed DOI

B Can Resveratrol Treatment Control the Progression of Induced Periodontal Disease? A Systematic Review and Meta-Analysis of Preclinical Studies

Meta Analysis Nutrients 2019

**Andrade et al., 2019** | Nutrients | Meta Analysis Andrade Eric Francelino, Orlando Débora Ribeiro, ... Pereira Luciano José. Can Resveratrol Treatment Control the Progression of Induced Periodontal Disease? A Systematic Review and Meta-Analysis of...

PubMed DOI

B A Meta-Analysis of the Impact of Resveratrol Supplementation on Markers of Renal Function and Blood Pressure in Type 2 Diabetic Patients on Hypoglycemic Therapy

Meta Analysis Molecules (Basel, Switzerland) 2020 n=388

**Nyambuya et al., 2020** | Molecules | Meta Analysis Nyambuya Tawanda M, Nkambule Bongani B, ... Dludla Phiwayinkosi V. A Meta-Analysis of the Impact of Resveratrol Supplementation on Markers of Renal Function and Blood Pressure in Type 2 Diabetic P...

PubMed DOI

B Activation of Brown Adipose Tissue and Promotion of White Adipose Tissue Browning by Plant-based Dietary Components in Rodents: A Systematic Review

Systematic Review Advances in nutrition (Bethesda, Md.) 2021 n=3919

**Osuna-Prieto et al., 2021** | Adv Nutr | Systematic Review Osuna-Prieto Francisco J, Martinez-Tellez Borja, ... Ruiz Jonatan R. Activation of Brown Adipose Tissue and Promotion of White Adipose Tissue Browning by Plant-based Dietary Components in R...

PubMed DOI

B The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis

Meta Analysis Medicina clinica 2022 n=871

**Abdelhaleem et al., 2022** | Med Clin (Barc) | Meta Analysis Abdelhaleem Ibrahim A, Brakat Aml M, ... Aboalfetoh Aya Y. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and met...

PubMed DOI

B Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review

Systematic Review Frontiers in physiology 2022 n=1171

**Zhou et al., 2022** | Front Physiol | Systematic Review Zhou Qian, Wang Yanmei, ... Chen Qiu. Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review. Front Physiol. 2022;13:795980. doi:10.3389...

PubMed DOI

Showing top 50 of 193 sources, sorted by quality score.

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Frequently Asked Questions

What is resveratrol and what are its main benefits?

Resveratrol is a polyphenol that can impact various metabolic and inflammatory markers in the body. There is moderate evidence suggesting it may help with blood pressure regulation, glucose management, and inflammation.

Does resveratrol help with Type 2 diabetes?

There is moderate evidence indicating that resveratrol supplementation can affect metabolic indicators and help with glucose management in patients with Type 2 diabetes.

Can resveratrol help with fatty liver disease?

There is moderate evidence suggesting that resveratrol may be effective in improving liver enzymes and overall disease status for those with Non-Alcoholic Fatty Liver Disease (NAFLD).

Does resveratrol help reduce inflammation?

Yes, meta-analyses of randomized clinical trials provide moderate evidence that resveratrol can change inflammatory mediators in the body.

Can I take resveratrol for weight loss?

There is currently weak evidence regarding the use of resveratrol for weight loss. While some randomized controlled trials suggest potential effects, the evidence is not yet strong.

Does resveratrol affect blood pressure?

There is moderate evidence from randomized controlled trials demonstrating that resveratrol supplementation can have an effect on blood pressure regulation.

Are there any side effects or drug interactions with resveratrol?

No specific drug interactions or contraindications have been documented in the provided research. However, you should always consult a healthcare provider before starting a new supplement.

What is the recommended dose of resveratrol?

Specific effective dose ranges were not explicitly detailed in the available research summaries. However, studies have noted that resveratrol can have a dose-response effect on blood lipid profiles.

Answers generated from research evidence. Not medical advice.