🟢 89/100

This product is generally safe

  • Niacin/Niacinamide: 47.5mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • B. bifidum: 275000000mg is 13750000.0× the Tolerable Upper Intake Level (20mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 36% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin/Niacinamide: 47.5mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ B. bifidum: 275000000mg is 13750000.0× the Tolerable Upper Intake Level (20mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Packet(s) Serving Size
30 Servings
Other Combinations Product Type
36% Evidence Coverage

Supplement Facts — Evidence Check

Calories
4.5 {Calories}
Calories from Fat
4.5 {Calories}
Saturated Fat
0.04 g (1% DV)
Polyunsaturated Fat
0.4 g
Monounsaturated Fat
0.06 g
Vitamin A
3750 IU (75% DV)
1150 mg (1917% DV)
📊 12.8× RDA — above typical dose (UL: 2000 mg) 📚 245 studies (Tier A: 6, B: 97)
RDA 90mg This product: 1150mg UL 2000mg
500 IU (125% DV)
✅ Within RDA (0.8× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0125mg UL 0.1mg
500 IU (1667% DV)
📊 22.3× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 335.0mg UL 1000mg
25 mg (1667% DV)
📊 20.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 25mg
12.5 mg (765% DV)
📊 9.6× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 12.5mg
47.5 mg (240% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 47.5mg UL 35mg
Vitamin B-6 Complex
25 mg (1250% DV)
200 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.2mg UL 1.0mg
62.5 mcg (1041% DV)
📊 26.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.0625mg
75 mcg (25% DV)
✅ 2.5× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.075mg
125 mg (1250% DV)
📊 25.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 125mg
Calcium
125 mg (13% DV)
50 mcg (33% DV)
✅ Within RDA (0.3× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.05mg UL 1.1mg
125 mg (31% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 125mg
6 mg (40% DV)
✅ Within RDA (0.5× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 6mg UL 40mg
50 mcg (71% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
0.5 mg (25% DV)
✅ Within RDA (0.6× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.5mg UL 10mg
2.5 mg (125% DV)
✅ 1.1× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2.5mg UL 11mg
50 mcg (42% DV)
✅ 1.4× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.05mg
25 mcg (33% DV)
✅ Within RDA (0.6× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.025mg UL 2mg
Potassium
25 mg (1% DV)
L. acidophilus
1150000000 CFU
L. rhamnosus
1150000000 CFU
L. Rhamnosus
775000000 CFU
S. Lactis
275000000 CFU
275000000 CFU
📊 Market median: 80.0mg (20 products) 📚 334 studies (Tier A: 8, B: 183)
This product: 275000000mg
275000000 CFU
⚠️ Exceeds Tolerable Upper Intake Level by 13750000.0× (UL: 20 mg) 📚 2 studies — no high-quality reviews
This product: 275000000mg UL 20mg
S. thermophilus
150000000 CFU
Proprietary Blend
215 mg
organic cold-pressed Oil of Evening Primrose
500 mg
400 mg
📊 Market median: 500.0mg (159 products)
Median 500.0mg This product: 400mg
Proprietary Organic Fruit and Vegetable Blend
175 mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 100mg
L-Proline
80 mg
Blackberry
40 mg
L-Cysteine/N-Acetyl L-Cysteine
38 mg
29 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 29mg
Celery powder
35 mg
Black Radish Powder
35 mg
Apricot powder
35 mg
Pycnogenol
25 mg
✅ 1.7× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 25mg UL 1000mg
25 mg
📊 Market median: 500.0mg (497 products) 📚 132 studies (Tier A: 0, B: 40)
This product: 25mg
Cauliflower
25 mg
25 mg
📊 Market median: 200.0mg (107 products)
Median 200.0mg This product: 25mg
25 mg
📊 Market median: 4.0mg (67 products)
Median 4.0mg This product: 25mg
Green Papaya extract
25 mg
Rose Hips
25 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 25mg
25 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 25mg
15 mg
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 15mg UL 3500mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 12.5mg
Apple Pectin
12.5 mg
12.5 mg
📊 Market median: 500.0mg (9 products)
This product: 12.5mg
12.5 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 12.5mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 12.5mg
Hesperidin
9 mg
7.5 mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 7.5mg
6 mg
📊 Market median: 500.0mg (19 products)
This product: 6mg
Glutamic Acid
5 mg
📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 3mg
1.6 mg
📊 Market median: 4.0mg (32 products)
This product: 1.6mg
1.5 mg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 1.5mg
0.4 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 0.4mg UL 20mg
Trace Elements
25 mcg
13 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.013mg UL 1.8mg

Other Ingredients

Gelatin Cellulose Vegetable Stearate L-Threonine Silica Glycerin Water Rosemary extract Mixed Tocopherols Ascorbyl Palmitate Citric Acid Safflower Oil

Label Claims — Verification

All Other
All Other (98% of products) Structure/Function (87% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: As a dietary supplement, adults take 1 pack daily with meals or as directed by your healthcare professional.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

🧪 Formulation Notes

This product contains NO yeast, soy protein, milk/dairy, sodium, starch, artificial coloring, preservatives or flavoring.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

FloraGlo(R) LUTEIN

PYCNOGENOL(R) (pine trees) NATURE'S SUPER ANTIOXIDANT FloraGLO(R) LUTEIN

Formula #65383

Product Details

UPC / SKU 3 10539 03549 8
DSLD Entry Date 2012-06-01
Product Type Other Combinations
Form Other (e.g. tea bag)
DSLD ID 9641
Data Updated 2026-04-11

Research Evidence

21 Research Sources
52 Avg Quality Score
13 Rct
4 Meta Analysis
2 Systematic Review
2 Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences
View all evidence for Alpha Lipoic Acid →

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