🟢 99/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 64% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Beige Caplet(s) Serving Size
30 Servings
Other Combinations Product Type
64% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
1500 mcg RAE (167% DV)
Vitamin C
300 mg (333% DV)
40 mcg (200% DV)
✅ 2.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.04mg UL 0.1mg
20.1 mcg (134% DV)
📊 Market median: 80.0mg (1390 products) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 0.0201mg UL 1000mg
80 mcg (67% DV)
✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.08mg
50 mg (4167% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (3846% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
50 mg (313% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
680 mcg DFE (170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 680mg UL 1.0mg
50 mcg (2083% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
50 mg (1000% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
10 mg (2% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 10mg UL 3500mg
Calcium
200 mg (15% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
100 mg (24% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
25 mg (227% DV)
✅ 2.3× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 25mg UL 40mg
200 mcg (364% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (222% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
2 mg (87% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
120 mcg (343% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
75 mcg (167% DV)
✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.075mg UL 2mg
📊 Market median: 320.0mg (426 products) 📚 24 studies (Tier A: 0, B: 5)
This product: 130mg
100 mg
📊 Market median: 500.0mg (143 products)
This product: 100mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 25mg
10 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 10mg
Pumpkin seed powder
10 mg
📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)
This product: 7.5mg
4 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 4mg
2 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 2mg UL 20mg
2 mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 2mg
Bacopa monnieri leaf extract
1.5 mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 1mg
📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)
This product: 1mg
1 mg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 1mg
Phosphatidyl Serine
1 mg
400 mcg
📊 Market median: 4.0mg (32 products)
This product: 0.4mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 0.5mg
50 mcg
📊 Market median: 4.0mg (47 products)
This product: 0.05mg
10 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.01mg UL 1.8mg
Beta-Cryptoxanthin
10 mcg

Other Ingredients

Microcrystalline Cellulose Cellulose Maltodextrin Hydroxypropyl Methylcellulose Hydroxypropylcellulose Dicalcium Phosphate Stearic Acid Food Starch Mannitol Gelatin Corn Starch Sugar Calcium Silicate natural Vanilla Mint flavor Sodium Ascorbate DL-Alpha Tocopherol Methylcellulose Glucose Syrup Stevia leaf extract Vegetable oil BHT BHA Povidone mixed Tocopherols Ascorbyl Palmitate Titanium Dioxide Caramel color Gum Arabic Polyethylene Glycol Talc Tricalcium Phosphate Paprika Extract Medium Chain Triglycerides Polyglycerol Fatty Acid Esters Polysorbate Sodium Aluminum Silicate Sodium Carboxymethylcellulose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Seniors/Mature (>50 Years) - Men ONLY Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take the contents of one pack daily with food.

⚠️ Warnings & Precautions

Keep out of reach of children.

Warning: Cancer and reproductive harm - www.P65Warnings.ca.gov.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery. Inform your physician of this product's biotin content before any lab test. Niacin may cause flushing.

Contains: Soybeans and fish (anchovy, mackerel, sardine, smelt, salmon, tuna, cod or a combination thereof).

🧪 Formulation Notes

This product contains EGCG from green tea.

No artificial flavors, gluten free. GF Gluten Free

Achieve your daily nutritional goals with customized ingredients plus multivitamins that have more antioxidant power than ever, contain 30 clinically studied ingredients.

Men’s health Contains a clinically studied men’s multivitamin formula shown to work better than a basic multivitamin.

Antioxidants Helps protect against harmful free radicals that can destroy healthy cells and promote the cell aging process.

Plus it contains clinically studied resVida resveratrol to enhance blood vessel dilation. Prostate health Features saw palmetto to support normal prostate function and lycopene, which may support prostate health. Mental sharpness Has ginkgo biloba, which supports mental sharpness.

Plus it contains clinically studied resVida resveratrol to enhance blood vessel dilation. Prostate health Features saw palmetto to support normal prostate function and lycopene, which may support prostate health. Mental sharpness Has ginkgo biloba, which supports mental sharpness.

Vitapak program with clinically studied multivitamin blend Antioxidants Heart health Prostate health Mental sharpness Clinically studied

30-day supply

Each pack contains: Mega Men 50 Plus Multivitamin

Additional Information

Store in a cool, dry place.

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a leading multivitamin formula based upon multivariate statistical analyses of a group of B vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid and vitamins B-6 and B-12) and key antioxidants and carotenoids (a group of beta-carotene, alpha-tocopherol, selenium, lutein and lycopene). Statistical improvements in SF-36 Vitality and Mental Health scores were also observed compared to placebo. A double-blind placebo-controlled, crossover study of 29 physically fit and healthy young adult male subjects averaging about 4 hours of exercise a week cycling to exhaustion at 80% V02 shows that these individuals were able to increase performance measure by time to exhaustion nearly 5 minutes longer than when taking placebo.

Product Details

DSLD Entry Date 2022-04-11
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand GNC Mega Men
Bundle 50 Plus
DSLD ID 259831
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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