🟢 99/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • AppleZinc(R) Apple Polyphenol Complex: 125mg is 3.1× the Tolerable Upper Intake Level (40mg)
  • 60% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ AppleZinc(R) Apple Polyphenol Complex: 125mg is 3.1× the Tolerable Upper Intake Level (40mg)

Label Data

6 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
500 mg (833% DV)
2000 IU (500% DV)
📊 3.3× RDA — above typical dose (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.05mg UL 0.1mg
200 IU (667% DV)
📊 8.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 134.0mg UL 1000mg
300 mcg (375% DV)
✅ 2.5× RDA — within safe limits 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.3mg
50 mg (3333% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
10 mg (588% DV)
📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 10mg
50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
50 mg (2500% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
800 mcg (200% DV)
✅ 2.0× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.8mg UL 1.0mg
500 mcg (8333% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
3000 mcg (1000% DV)
📊 100.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 3.0mg
50 mg (500% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
Calcium
300 mg (30% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
200 mg (50% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 200mg
30 mg (200% DV)
✅ 2.7× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 30mg UL 40mg
200 mcg (286% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
1 mg (50% DV)
✅ 1.1× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 1mg UL 10mg
2 mg (100% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
400 mcg (333% DV)
📊 11.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.4mg
150 mcg (200% DV)
📊 3.3× RDA — above typical dose (UL: 2 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.15mg UL 2mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 500mg
VitaVeggie(R) Vegetable Antioxidant Blend
500 mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 300mg
⚠️ Exceeds Tolerable Upper Intake Level by 3.1× (UL: 40 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 125mg UL 40mg
BerryVin high ORAC Berries
200 mg
Grape extract
📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)
This product: 120mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 100mg
100 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 100mg UL 1200mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 100mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 100mg
Mushroom Defense Blend
100 mg
50 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 50mg
Red Wine extract
25 mg
25 mg
📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)
This product: 25mg
6 mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 6mg
Black Pepper extract
5 mg
3 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 3mg UL 20mg
300 mcg
📊 Market median: 4.0mg (32 products)
This product: 0.3mg
natural Mixed Carotenoids
140 mcg

Other Ingredients

Gelatin Stearic Acid Magnesium Stearate Rice Flour Silicon Dioxide Dicalcium Phosphate

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Vitacost Synergy 3000(R) Multi-Vitamin Directions As a dietary supplement, take 6 capsules daily with foods including fat, preferably a healthy fat such as extra virgin olive oil, olives and nuts, to improve absorption of fat-soluble nutrients, or as directed by a physician.

⚠️ Warnings & Precautions

Warnings Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplement. Individuals taking anticoagulant drugs, such as coumadin or heparin, should avoid supplements containing Vitamin K, unless otherwise directed by a physician.

Contains: Soy.

🧪 Formulation Notes

Contains: Soy.

Additional Information

Store in a cool, dry place.

BioPerine(R)

Lutemax(R) FREE LUTEIN

Advan C

Betatene(R)

A comprehensive daily multi-vitamin featuring 22 essential nutrients plus fruit, vegetable and standardized botanical extracts.

BERRY VIN(TM) High ORAC Berries

L-OptiZinc(R)

ChromeMate(R)

AppleZin(TM)

PHYSICIAN FORMULATED

Product Details

UPC / SKU 8 44197 01115 5
DSLD Entry Date 2015-05-22
Product Type Other Combinations
Form Capsule
Brand Vitacost
DSLD ID 45624
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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