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Synergy 3000 Multi-Vitamin

product on market Capsule Vitacost Safety: 99/100
99/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • AppleZinc(R) Apple Polyphenol Complex: 125mg is 3.1× the Tolerable Upper Intake Level (40mg)
  • 60% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains essential vitamins A, C, D3, E, and K1, which are supported by strong evidence for maintaining immune function and bone health. These nutrients play critical roles in antioxidant defense and cellular regulation. The ingredient profile is associated with a high safety score, indicating a low risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

AppleZinc(R) Apple Polyphenol Complex: 125mg is 3.1× the Tolerable Upper Intake Level (40mg)

Label

Product Label

Label for Synergy 3000 Multi-Vitamin
Open Full PDF View on NIH DSLD →
Details

Label Data

6 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
500 mg (833% DV)
2000 IU (500% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
200 IU (667% DV)
8.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
300 mcg (375% DV)
2.5× RDA — within safe limits 275 studies (A:9, B:175)
50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
10 mg (588% DV)
7.7× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
800 mcg (200% DV)
2.0× RDA — within safe limits 226 studies (A:10, B:105)
500 mcg (8333% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
3000 mcg (1000% DV)
100.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
300 mg (30% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
200 mg (50% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
30 mg (200% DV)
2.7× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (286% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
1 mg (50% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
400 mcg (333% DV)
11.4× RDA — above typical dose 199 studies (A:1, B:55)
150 mcg (200% DV)
3.3× RDA — above typical dose (UL: 2 mg) 3 studies — no high-quality reviews
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
VitaVeggie(R) Vegetable Antioxidant Blend
500 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
Exceeds UL by 3.1× (UL: 40 mg) 263 studies (A:6, B:134)
BerryVin high ORAC Berries
200 mg
Grape extract
Market median: 120.0mg (440 products) 191 studies (A:1, B:71)
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
100 mg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
Mushroom Defense Blend
100 mg
50 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Red Wine extract
25 mg
25 mg
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
6 mg
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
Black Pepper extract
5 mg
3 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
300 mcg
Market median: 4.0mg (32 products)
natural Mixed Carotenoids
140 mcg

Other Ingredients

Gelatin Stearic Acid Magnesium Stearate Rice Flour Silicon Dioxide Dicalcium Phosphate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Vitacost Synergy 3000(R) Multi-Vitamin Directions As a dietary supplement, take 6 capsules daily with foods including fat, preferably a healthy fat such as extra virgin olive oil, olives and nuts, to improve absorption of fat-soluble nutrients, or as directed by a physician.

Warnings & Precautions

Warnings Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplement. Individuals taking anticoagulant drugs, such as coumadin or heparin, should avoid supplements containing Vitamin K, unless otherwise directed by a physician.

Contains: Soy.

Formulation Notes

Contains: Soy.

Additional Information

Store in a cool, dry place.

BioPerine(R)

Lutemax(R) FREE LUTEIN

Advan C

Betatene(R)

A comprehensive daily multi-vitamin featuring 22 essential nutrients plus fruit, vegetable and standardized botanical extracts.

BERRY VIN(TM) High ORAC Berries

L-OptiZinc(R)

ChromeMate(R)

AppleZin(TM)

PHYSICIAN FORMULATED

Metadata

Product Details

UPC / SKU8 44197 01115 5
DSLD Entry Date2015-05-22
Product TypeOther Combinations
FormCapsule
BrandVitacost
DSLD ID45624
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.