Regeneration

product on market Softgel Capsule NaturesPlus 🟢 Safety: 99/100
Brand: NaturesPlus
🟢 99/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 64% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

3 Softgel(s) Serving Size
30 Servings
Other Combinations Product Type
64% Evidence Coverage

Supplement Facts — Evidence Check

Calories
20 Calorie(s)
Total Fat
1.5 Gram(s) (2% DV)
Vitamin A
7508 mcg RAE (834% DV)
Vitamin C
200 mg (222% DV)
10 mcg (50% DV)
✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.01mg UL 0.1mg
134 mg (893% DV)
📊 8.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 134mg UL 1000mg
50 mg (4167% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (3846% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
50 mg NE (313% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
667 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 667mg UL 1.0mg
100 mcg (4167% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
100 mcg (2000% DV)
📊 Market median: 9.0mg (620 products) 📚 1 studies — no high-quality reviews
RDA 5mg This product: 0.1mg
50 mg (9% DV)
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 50mg UL 3500mg
Calcium
100 mg (8% DV)
Iron
4.5 mg (25% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
50 mg (12% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 50mg
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
20 mcg (36% DV)
✅ Within RDA (0.4× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.02mg UL 0.4mg
1 mg (111% DV)
✅ 1.1× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 1mg UL 10mg
5 mg (217% DV)
✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 5mg UL 11mg
50 mcg (143% DV)
✅ 1.4× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.05mg
20 mcg (44% DV)
✅ Within RDA (0.4× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.02mg UL 2mg
75 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 75mg
Juniper
50 mg
Celery
50 mg
Cayenne
50 mg
50 mg
📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)
This product: 50mg
50 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 50mg
50 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 50mg
Borage Seed Oil
31.5 mg
30 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 30mg
Parsley
27 mg
25 mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 25mg
10 mg
📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)
This product: 10mg
6.25 mg
📊 Market median: 450.0mg (390 products) 📚 155 studies (Tier A: 0, B: 63)
This product: 6.25mg
5 mg
📊 Market median: 100.0mg (120 products)
Median 100.0mg This product: 5mg
5 mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 5mg
5 mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 5mg
1 mg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 1mg UL 1.8mg

Other Ingredients

Safflower Seed Oil Gelatin Glycerin Potassium Glycerophosphate Magnesium Oxide purified Water Beeswax Sunflower Lecithin Caramel Annatto Sunflower Seed Oil

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, three softgels once daily with a meal.

⚠️ Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a physician or poison control center immediately.

🧪 Formulation Notes

Three tier revitalizing pyramid

Regeneration with Botanical Extracts and Antioxidants

Gluten free

Free from synthetic: Colors, preservatives. Free from milk, egg, fish, tree nuts, peanut, wheat, soy and sesame.

Nutritional support for natural energy production and overall well-being. Regeneration, an innovative advancement in multiple vitamin and mineral formulation is a three-tier revitalizing pyramid. Just three power-packed soft gelatin capsules provide a daily nutritional program, complete with a precisely engineered profile of nutrients and highly specialized botanical extracts. Tier 1 replenishes the body's nutrient stores with a high-energy profile of twenty-three vitamins and minerals, including mega-potencies of beta carotene and Vitamin E. These essential factors are vital for the liberation of energy from foods and the formation of structural components within the body. Tier 2 assists in the natural cleansing process. As toxins build up within the body, cellular function is compromised, resulting in low energy and poor health. Select botanical extracts and other healthful nutrients support the natural cleansing and rejuvenation process. Tier 3 helps support the body's natural defenses. The healthy effects of antioxidants are well documented throughout scientific literature. Botanical extracts such as standardized ginkgo biloba, wild grape seed extract and green tea are believed to be among the most powerful, natural antioxidants ever discovered. Regeneration, a three-tier revitalizing pyramid, is an unparalleled multiple vitamin and mineral formulation for cellular replenishment, cleansing and protection.

All minerals are whole brown rice amino acid chelates

Additional Information

Keep tightly closed in a cool, dry place.

Continued on back of label.

Product Details

UPC / SKU 0 97467 03285 9
DSLD Entry Date 2024-11-22
Product Type Other Combinations
Form Softgel Capsule
Brand NaturesPlus
DSLD ID 319210
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
PubMed DOI Cochrane
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
PubMed DOI Cochrane
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
PubMed DOI Cochrane
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
PubMed DOI Cochrane
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI
View all evidence for Vitamin A →

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