🟢 98/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 63% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Caplet(s) Serving Size
90 Servings
Other Combinations Product Type
63% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
1500 mcg (167% DV)
Vitamin C
200 mg (222% DV)
40 mcg (200% DV)
✅ 2.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.04mg UL 0.1mg
20.1 mg (134% DV)
✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 20.1mg UL 1000mg
80 mcg (67% DV)
✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.08mg
50 mg (4167% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (3846% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
50 mg (313% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
680 mcg DFE (170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 680mg UL 1.0mg
50 mcg (2083% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
50 mg (1000% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
10 mg (2% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 10mg UL 3500mg
Calcium
500 mg (38% DV)
50 mg (12% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 50mg
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
200 mcg (364% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (222% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
2 mg (87% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
120 mcg (343% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
75 mcg (167% DV)
✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.075mg UL 2mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 25mg
Fruit & Vegetable Blend
15 mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 14mg
10 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 10mg
4 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 4mg
2 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 2mg UL 20mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 2mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 1mg
📊 Market median: 100.0mg (173 products)
Median 100.0mg This product: 1mg
GABA
1 mg
1 mg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 1mg
400 mcg
📊 Market median: 4.0mg (32 products)
This product: 0.4mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 0.5mg
50 mcg
📊 Market median: 4.0mg (47 products)
This product: 0.05mg
10 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.01mg UL 1.8mg
Beta-Cryptoxanthin
10 mcg

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Methylcellulose Cellulose Stearic Acid Hydroxypropylcellulose Dicalcium Phosphate Magnesium Stearate Titanium Dioxide Polyethylene Glycol Talc natural Vanilla Mint flavor Chlorophyllin Stevia leaf extract

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (71% of products) Nutrient (61% of products) Approved Health (1% of products)

Target Groups

Adult Female (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take two caplets daily with food.

⚠️ Warnings & Precautions

Warning: Cancer and reproductive Harm - www.P65Warnings.ca.gov.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery. Inform your physician of this product's biotin content before any lab test. Niacin may cause a temporary flushing reaction.

This product contains EGCG from green tea.

Keep out of reach of children.

Contains: Soybeans, fish (anchovy, mackerel, sardine, smelt, salmon, tuna, cod or a combination thereof).

🧪 Formulation Notes

Conforms to USP <2091> for weight.

No artificial flavors, no wheat, gluten free, no dairy.

Start your nutrition regimen with the multivitamin blend that's designed for women and provides support for your overall health.

Clinically studied multivitamin blend Contains a clinically studied multivitamin blend shown to work better than a basic multivitamin

Immune support Supports Immune health with 30% more absorption of key Immune and oxidative defense nutrient

Brain health Has choline to support memory function, plus GABA and inositol for additional brain and nerve support

Beauty Includes biotin to support healthy hair, skin and nails, as well as ingredients to support skin hydration - plus, it’s packed with antioxidants to help protect against free radicals

Support for overall health & wellness Clinically proven to make you feel better Timed-release

Additional Information

Store in a cool, dry place.

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a leading multivitamin formula based upon multivariate statistical analyses of a group of B vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid and vitamins B-6 and B-12) and key antioxidants and carotenoids (a group of beta-carotene, alpha-tocopherol, selenium, lutein and lycopene). Statistical improvements in SF-36 Vitality and Mental Health scores were also observed compared to placebo.

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you're not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days and we'll either refund your money or find a replacement product that is right for you.

Living well starts here.

Product Details

DSLD Entry Date 2020-07-23
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand GNC Women's
DSLD ID 229043
Data Updated 2026-04-11

Research Evidence

566 Research Sources
56 Avg Quality Score
240 Meta Analysis
100 Clinical Trial
74 Systematic Review
71 Guideline
58 Rct
11 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
1 Observational
1 Openfda Safety
A Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency
Meta Analysis Nature medicine 2025
A Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Meta Analysis The Cochrane database of systematic reviews 2014
A Serum or plasma ferritin concentration as an index of iron deficiency and overload
Meta Analysis The Cochrane database of systematic reviews 2021
A Non-invasive diagnostic tests for Helicobacter pylori infection
Meta Analysis The Cochrane database of systematic reviews 2018
A Hypoxia-inducible factor stabilisers for the anaemia of chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2022
A Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations
Meta Analysis The Cochrane database of systematic reviews 2021
A Fortification of condiments and seasonings with iron for preventing anaemia and improving health
Meta Analysis The Cochrane database of systematic reviews 2023
A Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2024
A Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review
Meta Analysis Neuroscience and biobehavioral reviews 2025
View all evidence for Iron →

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