🟢 90/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 55% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

36 Gram(s) Serving Size
30 Servings
Other Combinations Product Type
55% Evidence Coverage

Supplement Facts — Evidence Check

Calories
130 {Calories}
Total Fat
2.5 g (4% DV)
Cholesterol
25 mg (8% DV)
Total Carbohydrates
15 g (5% DV)
Protein
10 g
Vitamin A
5000 IU (100% DV)
Vitamin C
300 mg (500% DV)
600 IU (150% DV)
✅ Within RDA (1.0× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.015000000000000001mg UL 0.1mg
30 IU (100% DV)
✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 20.1mg UL 1000mg
80 mcg (100% DV)
✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.08mg
50 mg (3330% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (2940% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
50 mg (2500% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
600 mcg (150% DV)
✅ 1.5× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.6mg UL 1.0mg
50 mcg (830% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
300 mcg (100% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
50 mg (500% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
Calcium
200 mg (20% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
50 mg (10% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 50mg
25 mg (100% DV)
✅ 2.3× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 25mg UL 40mg
200 mcg (265% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
2 mg (100% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
120 mcg (100% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
75 mcg (100% DV)
✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.075mg UL 2mg
150 mg (4% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 150mg
Sodium
200 mg (8% DV)
Potassium
250 mg (6% DV)
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 25mg
10 mg
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 10mg UL 3500mg
10 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 10mg
4 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 4mg
2 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 2mg UL 20mg
950 mcg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.95mg
950 mcg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 0.95mg
50 mcg
📊 Market median: 4.0mg (47 products)
This product: 0.05mg
50 mcg
📊 Market median: 4.0mg (32 products)
This product: 0.05mg
5 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.005mg UL 1.8mg
📊 Market median: 100.0mg (1 products) 📚 42 studies (Tier A: 1, B: 15)
This product: 8000mg
1000 mg
📊 Market median: 500.0mg (143 products)
This product: 1000mg
Proprietary Sports Blend
1000 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 1500mg
📊 Market median: 5.0mg (298 products) 📚 701 studies (Tier A: 5, B: 123)
This product: 1000mg
Essential Fatty Acid Blend
2 g
Antioxidant Fruit & Vegetable Blend
200 mg

Other Ingredients

Whey Protein concentrate nonfat Dry Milk Natural and Artificial Vanilla Cream Flavor DiArginine Malate Sodium Citrate Maltodextrin Xanthan Gum Lecithin Potassium Citrate Sodium Chloride Sodium Caseinate Potassium Chloride Dipotassium Phosphate Tricalcium Phosphate Mono & Diglycerides Sucralose Acesulfame Potassium

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (87% of products) Nutrient (16% of products)

Target Groups

Adult Male (18-50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: As a dietary supplement, mix two rounded scoops (36g) with 8 - fl. oz. of cold water or preferred cold beverage daily. Stir briskly or shake well in a closed container until completely mixed. May vary amount of liquid depending on thickness desired.

⚠️ Warnings & Precautions

Manufactured on equipment which processes products containing milk, egg, soybeans, shellfish, fish oil, tree nuts and peanut flavor.

CONTAINS: Milk, Soybeans and Wheat.

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

MEN'S

Premium formula designed for men who exercise regularly - Fuels lean muscle with 10 g of protein* - Supports recovery with L-glutamine* - Electrolyte replacement to fuel performan* - 1,000 mg of L-arginine to boost nitric oxide* - Promotes energy and metabolism*

Additional Information

Store in a cool, dry place.

Calories per gram: Fat 9 - Carbohydrates 4 - Protein 4

CODE 170269 KKG

Dr. Frank J. Costa, M.D., an internationally acclaimed urological surgeon and men’s health expert, is part of the GNC Medical Advisory Board.

GNC GUARANTEE Use any GNC supplement for as little as 10 days. If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!

MEGA MEN(R) SPORT Adequate nutrition is essential for both optimal health and athletic performance. Mega Men(R) Sport is the premium formula for physically active men whose bodies demand more than a multivitamin alone. Muscle Fuel - Features 10 g of protein, a compound providing a positive nitrogen balance in the body. Along with exercise, protein is a quality fuel for lean body mass.* - Features a creatine precursor blend that supports the body’s natural production of creatine, which plays an important role in protein synthesis.* Recovery Support - Enhanced with electrolytes which help to regulate body fluids.* Intense exercise can result in a loss of these valuable electrolytes, leading to muscle cramping. - Provides L-glutamine and branched chain amino acids (BCAA) that fuel muscle and help to reduce the amount of protein breakdown during intense exercise.* Sexual Health - Features 1,000 mg of L-arginine, an important amino acid and building block of nitric oxide which helps maintain blood vessel tone and plays a key role in sexual health.* Energy and Metabolism - Includes green tea and B-vitamins that are involved in energy production and carbohydrate metabolism.* Carbohydrates are an important fuel and primary source of energy during intense exercise. Immune Defense - Boosts the body's immunity with zinc, selenium and vitamins C and E.* - Enhanced with antioxidants that fight cell-damaging free radicals.*

Natural and Artificial Flavor

NEW

NOTICE: Significant product settling may occur.

One of “American’s Top Physicians,” Dr. Costa lectures nationally and internationally on men’s health topics. Dr. Costa is regularly featured in television, radio and newspaper interviews and has published articles in both professional journals and popular magazines.

Product Details

UPC / SKU 0 48107 09182 8
DSLD Entry Date 2011-10-26
Product Type Other Combinations
Form Powder
Brand GNC Mega Men
DSLD ID 1061
Data Updated 2026-04-11

Research Evidence

21 Research Sources
52 Avg Quality Score
13 Rct
4 Meta Analysis
2 Systematic Review
2 Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences
View all evidence for Alpha Lipoic Acid →

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