🟢 99/100

This product looks safe

  • Niacin/Niacinamide: 190mg is 5.4× the Tolerable Upper Intake Level (35mg)
  • Manganese: 20mg is 1.8× the Tolerable Upper Intake Level (11mg)
  • 50% of ingredients have research evidence
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Product Label

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Safety Alerts

⚠️ Niacin/Niacinamide: 190mg is 5.4× the Tolerable Upper Intake Level (35mg)
⚠️ Manganese: 20mg is 1.8× the Tolerable Upper Intake Level (11mg)

Label Data

7 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
25000 IU (500% DV)
Vitamin C
1200 mg (2000% DV)
400 IU (100% DV)
✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.01mg UL 0.1mg
400 IU (1333% DV)
📊 17.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 268.0mg UL 1000mg
70 mcg (88% DV)
✅ Within RDA (0.6× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.07mg
100 mg (6667% DV)
📊 83.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 100mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
190 mg (950% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 5.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 190mg UL 35mg
Vitamin B-6 Complex
100 mg (5000% DV)
800 mcg (200% DV)
✅ 2.0× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.8mg UL 1.0mg
100 mcg (1667% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
300 mcg (100% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
500 mg (5000% DV)
📊 100.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 500mg
Calcium
500 mg (50% DV)
200 mcg (133% DV)
✅ 1.3× RDA — within safe limits 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.2mg UL 1.1mg
500 mg (125% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 500mg
25 mg (167% DV)
✅ 2.3× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 25mg UL 40mg
200 mcg (286% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
20 mg (1000% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.8× (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 20mg UL 11mg
200 mcg (167% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg
100 mcg (133% DV)
✅ 2.2× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.1mg UL 2mg
Potassium
99 mg (3% DV)
60 mg
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 60mg UL 3500mg
100 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 100mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 100mg
50 mg
📊 Market median: 500.0mg (9 products)
This product: 50mg
50 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.05mg UL 1.8mg
1.5 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 1.5mg UL 20mg
Trace Elements
100 mcg
L-Cysteine/N-Acetyl-L-Cysteine
200 mg
12.5 mg
📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 12.5mg
Glutamic Acid
20 mg
114 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 114mg
Pycnogenol(R)
25 mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 50mg
📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)
This product: 40mg
Eleutherococcus Senticosus
25 mg
📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)
This product: 25mg
📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)
This product: 25mg
100 mg
📊 Market median: 500.0mg (497 products) 📚 132 studies (Tier A: 0, B: 40)
This product: 100mg
Green Papaya Extract
100 mg
Beet Extract
50 mg
Apple Pectin
50 mg
50 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 50mg
Rose Hips
100 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 100mg
📊 Market median: 500.0mg (19 products)
This product: 25mg
2.4 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 2.4mg
Hesperidin Complex
10 mg
Special Ultra Preventive(R) Green Base Proprietary Blend
550 mg
Ultra Preventive(R) Green Base

Other Ingredients

Cellulose Vegetable Stearate

Label Claims — Verification

All Other
All Other (100% of products) Structure/Function (84% of products) Nutrient (73% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Usage: As a dietary supplement, adults take 7 tablets daily or as directed by your healthcare professional. This product is best taken with meals.

⚠️ Warnings & Precautions

WARNING: This product contains Vitamin K, which interferes with the prescription drugs COumadin(R) and Warfarin. No not take this if taking either of these drugs.

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

🧪 Formulation Notes

This product contains NO yeast, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Pycnogenol(R) - French maritime bark extract-(TM)

Formula #84551

Product Details

UPC / SKU 3 10539 00276 6
DSLD Entry Date 2012-06-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 10257
Data Updated 2026-04-11

Research Evidence

332 Research Sources
59 Avg Quality Score
220 Meta Analysis
56 Systematic Review
30 Rct
16 Clinical Trial
3 Guideline
3 Regulatory Source
1 Narrative Review
1 Other
1 Openfda Safety
A Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism
Meta Analysis The Cochrane database of systematic reviews 2014
A Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome
Meta Analysis The Cochrane database of systematic reviews 2017
A Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or hip fracture repair
Meta Analysis The Cochrane database of systematic reviews 2016
A Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome
Meta Analysis The Cochrane database of systematic reviews 2020
A Direct factor Xa inhibitors versus low molecular weight heparins or vitamin K antagonists for prevention of venous thromboembolism in elective primary hip or knee replacement or hip fracture repair
Meta Analysis The Cochrane database of systematic reviews 2025
A Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation
Meta Analysis The Cochrane database of systematic reviews 2018
A Antiplatelet agents and anticoagulants for hypertension
Systematic Review The Cochrane database of systematic reviews 2022
A Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy
Meta Analysis The Cochrane database of systematic reviews 2012
A Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation
Meta Analysis The Cochrane database of systematic reviews 2013
A Anticoagulation for the long-term treatment of venous thromboembolism in patients with cancer
Meta Analysis The Cochrane database of systematic reviews 2014
View all evidence for Vitamin K →

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