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Neuro-Natural Serenity

product on market Tablet or Pill Xtendlife Safety: 100/100
100/100

This product looks safe

  • Folic Acid: 323mg is 323.0× the Tolerable Upper Intake Level (1.0mg)
  • 57% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The product contains thiamine, a vitamin essential for glucose metabolism and nerve function, supported by strong clinical evidence. Other listed components are basic macronutrients providing general energy. Overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folic Acid: 323mg is 323.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Neuro-Natural Serenity
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Tablet(s)
Serving Size
15
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
20 Calorie(s)
Total Fat
0.5 Gram(s) (1% DV)
Total Carbohydrates
2 Gram(s) (1% DV)
Protein
1 Gram(s) (2% DV)
22 mg (1467% DV)
18.3× RDA — above typical dose 76 studies (A:0, B:33)
10 mg (588% DV)
7.7× RDA — above typical dose 13 studies (A:0, B:1)
10 mg (500% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
323 mg (81% DV)
Exceeds UL by 323.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
1994 mcg (665% DV)
66.5× RDA — above typical dose 27 studies (A:0, B:11)
90 mcg (129% DV)
1.6× RDA — within safe limits 173 studies (A:0, B:67)
54 mcg (45% DV)
1.5× RDA — within safe limits 199 studies (A:1, B:55)
Market median: 300.0mg (159 products)
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
247 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
Bacopa leaf extract
200 mg
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Market median: 250.0mg (60 products) 7 studies (A:0, B:1)
200 mg
Market median: 500.0mg (223 products) 24 studies (A:0, B:1)
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
160 mg
Market median: 60.0mg (94 products) 13 studies (A:0, B:7)
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
D-Phenylalanine
149 mg
L-Carnosine
148 mg
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
128 mg
Market median: 200.0mg (52 products) 12 studies (A:0, B:6)
Within RDA (0.2× RDA) 38 studies (A:1, B:7)
Market median: 400.0mg (142 products) 10 studies (A:0, B:2)
Hop cone powder
100 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
98 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Market median: 250.0mg (182 products) 10 studies (A:0, B:2)
73 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 120.0mg (440 products) 191 studies (A:1, B:71)
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)
Eleuthero root extract
50 mg
Papain
50 mg
50 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
L-Valine
50 mg
49 mg
Market median: 420.0mg (227 products)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
49 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Phosphatidyl L-Serine
20 mg
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
Vinpocetine
14 mg
Piperine
9.5 mg
200 mcg
Market median: 0.15mg (41 products)
Pancreatic Enzyme Blend
120 mg

Other Ingredients

Microcrystalline Cellulose Enteric Coating Dextrose Maltodextrin Silicon Dioxide Sodium Carboxymethyl Cellulose Magnesium Stearate Dicalcium Phosphate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions For Use Adults: 6 tablets per day. Age 12-18 Years: 3 tablets per day. Take all tablets first thing in the morning or split into 2 doses, in the morning and later in the day.

Warnings & Precautions

Contains soy.

Formulation Notes

Contains soy.

Does not contain dairy, gluten, shellfish or peanut.

Additional Information

Store in a cool, dry place.

L1085-11

Best quality guarantee Advanced formula enteric coated

Made in New Zealand

Metadata

Product Details

DSLD Entry Date2018-01-25
Product TypeOther Combinations
FormTablet or Pill
DSLD ID82185
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.