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Energy & Metabolism

product on market Other (e.g. tea bag) GNC Mega Men Safety: 89/100
89/100

This product is generally safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 69% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The profile contains essential fat-soluble and water-soluble vitamins that support immune function and metabolic health. There is strong research evidence for the roles of vitamins A, C, D, E, and K in maintaining cellular health. The evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Energy & Metabolism
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
45
Servings
Other Combinations
Product Type
69%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
300 mg (500% DV)
1600 IU (400% DV)
2.7× RDA — within safe limits 608 studies (A:16, B:251)
30 IU (100% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
80 mcg (100% DV)
Within RDA (0.7× RDA) 275 studies (A:9, B:175)
50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (2941% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
50 mcg (833% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
200 mg (20% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
100 mg (25% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
25 mg (167% DV)
2.3× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (286% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
2 mg (100% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
120 mcg (100% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (100% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
Energy & Metabolism Blend
119 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
10 mg
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
10 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
4 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
2 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
950 mcg
Market median: 10.0mg (35 products) 6 studies (A:0, B:2)
190 mcg
Market median: 4.0mg (32 products)
50 mcg
Market median: 4.0mg (47 products)
10 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)

Other Ingredients

Cellulose Titanium Dioxide Vegetable Acetoglycerides Caramel color Ethyl Vanillin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take two caplets daily with food.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Formulation Notes

CONTAINS: Fish and Soybeans.

No Artificial Colors, No Wheat, No Gluten, No Dairy, Yeast Free.

Additional Information

Store in a cool, dry place.

2X MORE D-3

ACTUAL SIZE

CLINICALLY STUDIED

CLINICALLY STUDIED MULTIVITAMIN

CODE 177512 ILG

Compared to leading brands.

Energy

Frank J. Costa, M.D., an acclaimed urological surgeon and men's health expert, is part of the GNC Medical Advisory Board. One of "America's Top Physicians," Dr. Costa lectures nationally and internationally on men's health topics. Dr. Costa is regularly featured in television, radio and newspaper interviews and has published articles in both professional journals and popular magazines. "Lack of energy and slow metabolisms are common concerns of many of my patients. When a regular multivitamin isn't enough, I suggest Mega Men(R) Energy & Metabolism for the extra boost to help them through their busy schedules."

GNC GUARANTEE Use any GNC supplement for as little as 10 days. If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!

GNC QUALITY COMMITMENT GNC, the leader in the development and manufacture of dietary supplements, is committed to producing the highest quality products available. This commitment begins with quality designed supplement formulations. Every raw material that goes into a GNC supplement is guaranteed as to quality and potency. Each product is dated and then shipped immediately to our stores, so you can be sure you are purchasing the freshest supplements available. At GNC, we extend our quality commitment to you by offering our money-back guarantee.

MEGA MEN(R) ENERGY & METABOLISM Taking a daily multivitamin keeps you on the right track for filling your nutritional gaps. Mega Men(R) Energy & Metabolism is an enhanced multivitamin that provides the same clinically studied base as our Mega Men(R) formula with ingredients that help boost your energy! Advanced Nutritional Support Includes 1,600 IU of vitamin D-3. Emerging research suggests that adequate daily vitamin D intake may play a role in supporting colon and immune health. Supplies B-vitamins that are essential for energy production and metabolism. Calorie Burning Support Features an energy and metabolism blend that helps boost energy and metabolism and supports calorie burning. The components in this blend also help support mental focus. Antioxidant Protection Contains a premium blend of antioxidants including selenium, vitamin C and vitamin E to aid in supporting the body's immunity. Combines lutein and zeaxanthin, to support eye health, with lycopene, an antioxidant from tomatoes to support cardiovascular health. Timed-release caplets provide a gradual release of vital nutrients.

Timed-Release

With 1,600 IU of vitamin D-3 for colon health and immune support Boosts energy and metabolism Supports mental focus Calorie burning support

Confroms to USP <2091> for weight.

Please recycle this box.

Metadata

Product Details

DSLD Entry Date2011-10-26
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandGNC Mega Men
DSLD ID781
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.