Life Extenstion Mix Capsules Without Copper

product on market Capsule Life Extension 🟢 Safety: 99/100
Brand: Life Extension
🟢 99/100

This product looks safe

  • Niacin: 862mg is 24.6× the Tolerable Upper Intake Level (35mg)
  • Vitamin B6: 105mg is 1.1× the Tolerable Upper Intake Level (100mg)
  • 58% of ingredients have research evidence
D Label Compliance Grade

Product Label

Label for Life Extenstion Mix Capsules Without Copper
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Safety Alerts

⚠️ Niacin: 862mg is 24.6× the Tolerable Upper Intake Level (35mg)
⚠️ Vitamin B6: 105mg is 1.1× the Tolerable Upper Intake Level (100mg)

Label Data

7 Capsule(s) Serving Size
35 Servings
Other Combinations Product Type
58% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
2000 mg (3333% DV)
2000 IU (500% DV)
📊 3.3× RDA — above typical dose (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.05mg UL 0.1mg
100 IU (333% DV)
📊 4.5× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 67.0mg UL 1000mg
125 mg (8333% DV)
📊 104.2× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 125mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
862 mg (4310% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 24.6× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 862mg UL 35mg
105 mg (5250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 105mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
600 mcg (10000% DV)
📊 250.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.6mg
3000 mcg (1000% DV)
📊 100.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 3.0mg
600 mg (6000% DV)
📊 120.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 600mg
Calcium
460 mg (46% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
400 mg (100% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 400mg
35 mg (233% DV)
📊 3.2× RDA — above typical dose (UL: 40 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 35mg UL 40mg
200 mcg (286% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
1 mg (50% DV)
✅ Within RDA (0.4× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 1mg UL 11mg
500 mcg (417% DV)
📊 14.3× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.5mg
125 mcg (167% DV)
✅ 2.8× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.125mg UL 2mg
Potassium
35 mg (1% DV)
N-Acetyl-L-Cysteine
600 mg
200 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 200mg
250 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 250mg
150 mg
✅ Within RDA (0.3× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 150mg UL 3500mg
120 mg
✅ Within RDA (0.2× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 120mg UL 3500mg
3 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 3mg UL 20mg
100 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 100mg
200 mg
📊 Market median: 983.0mg (16 products) 📚 7 studies (Tier A: 0, B: 1)
This product: 200mg
Broccoli concentrate blend
725 mg
325 mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 325mg
Acerola extract
300 mg
Fruit/Berry Proprietary Blend
200 mg
Wild Blueberry Anthocyanin extract
150 mg
100 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 100mg
Maqui berry (Aristotelia chilensis) Anthocyanin extract
100 mg
85 mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 85mg
85 mg
📊 Market median: 250.0mg (182 products) 📚 10 studies (Tier A: 0, B: 2)
This product: 85mg
60 mg
📊 4.0× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 60mg UL 1000mg
30 mg
📊 Market median: 100.0mg (120 products)
Median 100.0mg This product: 30mg
25 mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 25mg
25 mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 25mg
15 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 15mg
Delphinidins
2 mg
15 mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 15mg
Olive extract
12.5 mg
10 mg
📊 Market median: 200.0mg (52 products) 📚 10 studies (Tier A: 0, B: 6)
This product: 10mg
Luteolin
8 mg
3 mg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 3mg
Cyanidin-3-Glucoside
1.25 mg
0.5 mg
📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)
This product: 0.5mg
Apigenin
5 mg

Other Ingredients

Gelatin Microcrystalline Cellulose Vegetable Stearate Silica Maltodextrin Medium Chain Triglycerides

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (100% of products) Structure/Function (75% of products) Nutrient (48% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Take fourteen (14) capsules per day in divided doses with meals, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Caution: Temporary flushing, itching, rash, or gastric disturbances may occur. Liver function testing is recommended when niacin is taken in excess of 500 mg daily. Those with gout or liver disease should avoid taking high doses of niacin.

Consult with your doctor before using this product if you are taking anticoagulant medications. Individuals consuming more than 2,000 IU/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement.

Vitamin D supplementation is not recommended for individuals with high blood calcium levels. Individuals with in-born errors or copper metabolism (e.g. Wilson's disease) should avoid daily, chronic use of this product.

Contains soybeans.

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Warning: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

🧪 Formulation Notes

Contains soybeans.

Additional Information

Scan for product info

QE02164A

State-of-the-art Multi-nutrient formula

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Store tightly closed in a cool, dry place.

Product Details

UPC / SKU 7 37870 21644 5
DSLD Entry Date 2017-06-23
Product Type Other Combinations
Form Capsule
Brand Life Extension
DSLD ID 74683
Data Updated 2026-04-11

Research Evidence

42 Research Sources
53 Avg Quality Score
20 Meta Analysis
10 Systematic Review
9 Rct
1 Observational
1 Regulatory Source
B Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis
Meta Analysis Nutrition reviews 2025
PubMed DOI
B Blood Trace Element Status in Multiple Sclerosis: a Systematic Review and Meta-analysis
Meta Analysis Biological trace element research 2022
PubMed DOI
B Micronutrient deficiency risk in long-term enterally fed patients: A systematic review
Systematic Review Clinical nutrition ESPEN 2022
PubMed DOI
B Essential Trace Element Status in Systemic Lupus Erythematosus: a Meta-analysis Based on Case-Control Studies
Meta Analysis Biological trace element research 2023
PubMed DOI
B Association between serum copper/zinc ratio and lung cancer: A systematic review with meta-analysis
Meta Analysis Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2022
PubMed DOI
B Vacuolated Marrow Cytopenias from Copper Deficiency to UBA1-Mutant VEXAS: Molecular Landscape, Systematic Review, and Cost-Efficient Diagnostic Algorithm
Systematic Review International journal of molecular sciences 2025
PubMed DOI
B Parenteral trace element provision: recent clinical research and practical conclusions
Systematic Review European journal of clinical nutrition 2016
PubMed DOI
B Copper Deficiency: A Frequently Overlooked Complication After MBS-A Systematic Review and Meta-analysis
Meta Analysis Obesity surgery 2025
PubMed DOI
B Copper in colorectal cancer patients: a systematic review and meta-analysis
Meta Analysis Carcinogenesis 2025
PubMed DOI
B Zinc deficiency and zinc/copper ratio imbalance in autism spectrum disorder: a reanalysis of six multinational studies
Meta Analysis Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2026
PubMed DOI
View all evidence for Copper →

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