Mega Men Energy & Metabolism by GNC Mega Men — Ingredients, Evidence & Safety

🟢 88/100

This product is generally safe

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
Selenium: 25mg is 62.5× the Tolerable Upper Intake Level (0.4mg)
Contains proprietary blend — exact ingredient amounts not disclosed
69% of ingredients have research evidence

D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

⚠️ Selenium: 25mg is 62.5× the Tolerable Upper Intake Level (0.4mg)

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

2 Beige Caplet(s) Serving Size

Other Combinations Product Type

69% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

5000 IU (100% DV)

Vitamin C

300 mg (500% DV)

Vitamin D

1600 IU (400% DV)

✅ 2.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.04mg UL 0.1mg

Vitamin E

30 IU (100% DV)

✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 20.1mg UL 1000mg

Vitamin K

80 mcg (100% DV)

✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.08mg

Thiamine

50 mg (3333% DV)

📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 50mg

Riboflavin

50 mg (2941% DV)

📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 50mg

Niacin

50 mg (250% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 50mg UL 35mg

Vitamin B6

50 mg (2500% DV)

📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 50mg UL 100mg

Folic Acid

400 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.4mg UL 1.0mg

Vitamin B12

50 mcg (833% DV)

📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.05mg

Biotin

300 mcg (100% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

50 mg (20% DV)

📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 50mg

Calcium

200 mg (20% DV)

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

100 mg (25% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 100mg

Zinc

25 mg (167% DV)

✅ 2.3× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 25mg UL 40mg

Selenium

25 mg (286% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 62.5× (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 25mg UL 0.4mg

Copper

2 mg (100% DV)

✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 2mg UL 10mg

Manganese

2 mg (100% DV)

✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2mg UL 11mg

Chromium

120 mcg (100% DV)

📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.12mg

Molybdenum

75 mcg (100% DV)

✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.075mg UL 2mg

Energy & Metabolism Blend

119 mg

Proprietary Amino Acid Blend

100 mg

📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)

This product: 100mg

Green Tea extract

40 mg

📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)

This product: 40mg

Alpha-Lipoic Acid

25 mg

📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews

This product: 25mg

Choline Bitartrate

10 mg

📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 10mg UL 3500mg

Inositol

10 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 10mg

Silica

4 mg

📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)

This product: 4mg

Boron

2 mg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 2mg UL 20mg

Lutemax 2020 Lutein

950 mcg

📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.95mg

Lycopene

950 mcg

📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)

This product: 0.95mg

Zeaxanthin

190 mcg

📊 Market median: 4.0mg (32 products)

This product: 0.19mg

Astaxanthin

50 mcg

📊 Market median: 4.0mg (47 products)

This product: 0.05mg

Vanadium

10 mcg

📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.01mg UL 1.8mg

Other Ingredients

Cellulose Titanium Dioxide Vegetable Acetoglycerides Caramel color Ethyl Vanillin

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult Male (18-50 Years)

Product Information

📋 Directions for Use

Discontinue use two weeks prior to surgery.

DIRECTIONS: As a dietary supplement, take contents of one packet daily with food.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

🧪 Formulation Notes

Each pack contains: Mega Men(R) Energy & Metabolism

CONTAINS: Fish and Soybeans.

Each serving supplies approximately 100 mg Caffeine

Additional Information

Store in a cool, dry place.

PHYSICIAN ENDORSED

Energy

CODE 346922 APG

GNC QUALITY COMMITMENT For more than 78 years, GNC has been the leader in the development of superior nutritional supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality controls.

In a randomized double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blend in this product for six weeks experienced statistically significant improvements on markers of b vitamin and antioxidant status, as well as improvements in SF-36 Vitality and Mental Health scores compared to those taking a placebo.

GNC GUARANTEE If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you LIVE WELL.

Clinically studied multivitamin with 1,600 IU of vitamin D-3 Boosts energy, fuels muscles & supports exercise recovery Improves mental alertness & energy Helps maintain healthy cholesterol & blood pressure levels with concentrated fish oil

BONUS SIZE- ONE EXTRA WEEK FREE!

Product Details

DSLD Entry Date 2014-05-23

Product Type Other Combinations

Form Unknown

Brand GNC Mega Men

Bundle Energy & Metabolism

DSLD ID 33660

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →