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Energy & Metabolism

product on market Unknown GNC Mega Men Safety: 89/100
89/100

This product is generally safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 69% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The product contains a blend of essential vitamins A, C, D, E, and K, which support immune function and metabolic health. There is strong research evidence supporting the roles of these micronutrients in maintaining cellular health. The overall safety profile is high, though evidence coverage for the specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Energy & Metabolism
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
108
Servings
Other Combinations
Product Type
69%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
300 mg (500% DV)
1600 IU (400% DV)
2.7× RDA — within safe limits 608 studies (A:16, B:251)
30 IU (100% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
80 mcg (100% DV)
Within RDA (0.7× RDA) 275 studies (A:9, B:175)
50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (2941% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
50 mcg (833% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
50 mg (20% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
100 mg (25% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
25 mg (167% DV)
2.3× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (286% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
2 mg (100% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
120 mcg (100% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (100% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
Energy & Metabolism Blend
119 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
10 mg
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
10 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
4 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
2 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
950 mcg
Market median: 10.0mg (35 products) 6 studies (A:0, B:2)
190 mcg
Market median: 4.0mg (32 products)
5 mcg
Market median: 4.0mg (47 products)
10 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)

Other Ingredients

Cellulose Titanium Dioxide Vegetable Acetoglycerides Caramel color Ethyl Vanillin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: As a dietary supplement, take two caplets daily with food. For maximum benefits, take as directed every day.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

Formulation Notes

No Artificial Colors, No Wheat, No Gluten, No Dairy, Yeast Free.

CONTAINS: Fish and Soybeans

Each serving supplies approximately 100 mg of caffeine.

Additional Information

Conforms to USP <2091> for weight.

This product is endorsed by Dr. Frank Costa.

BONUS SIZE 20% MORE FREE

Energy

CODE 177532 IOG

Store in a cool, dry place.

Scientifically formulated multivitamin designed to fuel muscles, boost energy & enhance calorie burnung

Timed-Release

PHYSICIAN ENDORSED

Metadata

Product Details

UPC / SKU0 48107 13516 4
DSLD Entry Date2014-05-23
Product TypeOther Combinations
FormUnknown
BrandGNC Mega Men
DSLD ID33192
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.