🟢 89/100

This product is generally safe

Niacin: 38mg is 1.1× the Tolerable Upper Intake Level (35mg)
Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)
Contains proprietary blend — exact ingredient amounts not disclosed
56% of ingredients have research evidence

D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains essential vitamins A and C, which have strong evidence for supporting immune function and cellular protection. These micronutrients act as antioxidants to mitigate oxidative stress. Due to the very low evidence coverage, the overall clinical data for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Safety Alerts

⚠️ Niacin: 38mg is 1.1× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

9 Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

56% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 Calorie(s)

Total Fat

1 Gram(s) (1% DV)

Cholesterol

5 mg (2% DV)

Vitamin A

1500 mcg (167% DV)

Vitamin C

1125 mg (1250% DV)

Vitamin D

12.5 mcg (63% DV)

✅ Within RDA (0.8× RDA of 0.015 mg) 📚 608 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.0125mg UL 0.1mg

Vitamin E

34 mg (223% DV)

✅ 2.3× RDA — within safe limits 📚 179 studies (Tier A: 3, B: 90)

RDA 15mg This product: 34mg UL 1000mg

Vitamin K

50 mcg (42% DV)

✅ Within RDA (0.4× RDA of 0.12 mg) 📚 275 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.05mg

Thiamine

12.5 mg (1042% DV)

📊 10.4× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 12.5mg

Riboflavin

16.7 mg (1285% DV)

📊 12.8× RDA — above typical dose 📚 13 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 16.7mg

Niacin

38 mg (234% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 35 mg) 📚 196 studies (Tier A: 5, B: 63)

RDA 14mg This product: 38mg UL 35mg

Vitamin B6

10 mg (588% DV)

📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 114 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 10mg UL 100mg

Folate

333 mcg DFE (83% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 333.0× (UL: 1.0 mg) 📚 226 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 333mg UL 1.0mg

Vitamin B12

500 mcg (20833% DV)

📊 208.3× RDA — above typical dose 📚 139 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.5mg

Biotin

400 mcg (1333% DV)

📊 13.3× RDA — above typical dose 📚 27 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.4mg

Pantothenic Acid

25 mg (500% DV)

📊 5.0× RDA — above typical dose 📚 2 studies — no high-quality reviews

RDA 5mg This product: 25mg

Choline

10 mg (2% DV)

📊 Market median: 125.0mg (294 products) 📚 38 studies (Tier A: 1, B: 7)

RDA 550mg This product: 10mg UL 3500mg

Calcium

100 mg (8% DV)

Iodine

100 mcg (67% DV)

✅ Within RDA (0.7× RDA of 0.15 mg) 📚 245 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.1mg UL 1.1mg

Magnesium

100 mg (24% DV)

✅ Within RDA (0.2× RDA of 420 mg) 📚 316 studies (Tier A: 8, B: 159)

RDA 420mg This product: 100mg UL 350mg

Zinc

7.5 mg (68% DV)

✅ Within RDA (0.7× RDA of 11 mg) 📚 263 studies (Tier A: 6, B: 134)

RDA 11mg This product: 7.5mg UL 40mg

Selenium

100 mcg (182% DV)

✅ 1.8× RDA — within safe limits 📚 173 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.1mg UL 0.4mg

Copper

1 mg (111% DV)

✅ 1.1× RDA — within safe limits 📚 37 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 1mg UL 10mg

Manganese

1 mg (43% DV)

✅ Within RDA (0.4× RDA of 2.3 mg) 📚 9 studies — no high-quality reviews

RDA 2.3mg This product: 1mg UL 11mg

Chromium

100 mcg (286% DV)

✅ 2.9× RDA — within safe limits 📚 199 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.1mg

Potassium

50 mg (1% DV)

Boron Glycinate

1 mg

📊 Market median: 3.0mg (58 products) 📚 3 studies — no high-quality reviews

This product: 1mg UL 20mg

Vanadium

50 mcg

📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.05mg UL 1.8mg

Proprietary Mixed Carotenoid Blend

289 mcg

Inositol

25 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 25mg

Kre-Alkalyn

1375 mg

Coenzyme Q10

145 mg

📊 Market median: 100.0mg (283 products) 📚 144 studies (Tier A: 1, B: 64)

This product: 145mg UL 1200mg

Alpha Ketoglutarate

25 mg

N-Acetyl-L-Cysteine

75 mg

Alpha Lipoic Acid

50 mg

📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews

This product: 50mg

L-Carnosine

25 mg

L-Glutamine

1000 mg

📊 Market median: 420.0mg (227 products)

Median 420.0mg This product: 1000mg

PowerGrape Grape (Vitis vinifera) extract

100 mg

📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)

This product: 100mg

Superfruit Antioxidant Blend

25 mg

Green Tea (Camellia sinensis) extract

25 mg

📊 Market median: 260.0mg (249 products) 📚 158 studies (Tier A: 4, B: 61)

This product: 25mg

Fish Oil concentrate

1000 mg

📊 Market median: 750.0mg (447 products) 📚 393 studies (Tier A: 18, B: 204)

This product: 1000mg UL 3000mg

Other Ingredients

Vegetarian Capsule Gelatin Capsule hypoallergenic Plant Fiber Ascorbyl Palmitate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommendations: As a dietary supplement, take 1 packet daily (9 capsules), with a meal.

⚠️ Warnings & Precautions

Contains fish (anchovies, sardines, mackerel)

Warning: Vitamin K may be contraindicated with Coumadin (Warfarin).

If you are pregnant or lactating, have any health condition or are taking any medication, particularly blood thinning medication, consult your health professional before use.

Keep out of the reach of children.

This product was sealed for your protection. Do not use if box or contents are open or damaged.

🧪 Formulation Notes

Comprehensive daily packet providing core nutrients, fish oil, antioxidants, glutamine, and energy cofactors including CoQ10 and Kre-Alkalyn

Contains fish (anchovies, sardines, mackerel)

with Metafolin L-5-MTHF

Gluten-free & Non-GMO

Additional Information

Store in a cool, dry place.

Scan to learn more about our hypoallergenic supplements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

v10 code: APPB3

Product Details

UPC / SKU 7 66298 01276 6

DSLD Entry Date 2018-10-25

Product Type Other Combinations

Form Capsule

Brand Pure Encapsulations

DSLD ID 182730

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →