🟢 99/100

This product looks safe

  • Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)
  • 56% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

54.38 Gram(s) Serving Size
14 Servings
Other Combinations Product Type
56% Evidence Coverage

Supplement Facts — Evidence Check

Calories
180 Calorie(s)
Total Fat
3 Gram(s) (4% DV)
Total Carbohydrates
11 Gram(s) (4% DV)
Protein
26 Gram(s) (52% DV)
Vitamin A
750 mcg RAE (83% DV)
Vitamin C
250 mg (278% DV)
2.5 mcg (13% DV)
✅ Within RDA (0.2× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0025mg UL 0.1mg
84 mg (560% DV)
📊 5.6× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 84mg UL 1000mg
15 mg (1250% DV)
📊 12.5× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 15mg
5 mg (385% DV)
📊 3.8× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 5mg
40 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 40mg UL 35mg
6 mg (353% DV)
📊 4.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 6mg UL 100mg
340 mcg DFE (85% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 340.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 340mg UL 1.0mg
50 mcg (2083% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
150 mcg (500% DV)
📊 5.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.15mg
35 mg (700% DV)
📊 7.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 35mg
100 mg (18% DV)
✅ Within RDA (0.2× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 100mg UL 3500mg
Calcium
320 mg (25% DV)
600 mg (48% DV)
✅ Within RDA (0.9× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 600mg UL 4000mg
60 mcg (40% DV)
✅ Within RDA (0.4× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.06mg UL 1.1mg
280 mg (67% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 280mg
10 mg (91% DV)
✅ Within RDA (0.9× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 10mg UL 40mg
100 mcg (182% DV)
✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.1mg UL 0.4mg
2 mg (87% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
60 mcg (171% DV)
✅ 1.7× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.06mg
35 mcg (78% DV)
✅ Within RDA (0.8× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.035mg UL 2mg
Sodium
70 mg (3% DV)
Potassium
65 mg (1% DV)
LignaMax
6000 mg
4316 mg
📊 Market median: 420.0mg (227 products)
Median 420.0mg This product: 4316mg
📊 Market median: 250.0mg (182 products) 📚 10 studies (Tier A: 0, B: 2)
This product: 625mg
L-Glycine
477 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 250mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 250mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 250mg
250 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 250mg
200 mg
📊 Market median: 500.0mg (19 products)
This product: 200mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 200mg
175 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 175mg
📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)
This product: 150mg
📊 Market median: 600.0mg (7 products) 📚 39 studies (Tier A: 2, B: 13)
This product: 150mg
Protease
150 mg
📊 Market median: 1000.0mg (2 products)
This product: 120mg
Watercress (Rorippa nasturtium-aquaticum) aerial extract
100 mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 82mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 80mg

Other Ingredients

Rice Protein Vanilla Flavor, Natural Guar Gum Xanthan Gum Maltodextrin Stevia Extract Salt

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Stir or blend 2 scoops (54.38 grams) into 8 ounces of water. Take once per day or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Caution: Keep out of reach of children.

If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

This product is not labeled for sale in the state of California.

🧪 Formulation Notes

Does not contain: milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, artificial colors, sweeteners or preservatives.

B Activated B-Vitamins Rapid Uptake 5-MTHF biologically active folate

Professional quality formulas Gastrointestinal & hepatic support formula

Now with 5-MTHF active folate 26 g rice protein per serving

GF Gluten-free

Vegetarian

Additional Information

Storage: Keep tightly closed in a cool, dry place. Contents sold by weight, not volume. Some settling may occur during shipping and handling. The amount of product contained in 2 scoops may be above or below 54.38 grams due to variations in handling and product density.

Product Details

UPC / SKU 8 12527 01136 6
DSLD Entry Date 2025-01-23
Product Type Other Combinations
Form Powder
Brand NuMedica
DSLD ID 323681
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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