🟢 89/100

This product is generally safe

Niacin: 86mg is 2.5× the Tolerable Upper Intake Level (35mg)
Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
Contains proprietary blend — exact ingredient amounts not disclosed
51% of ingredients have research evidence

D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Vitamin A and C are supported by strong evidence for their roles in immune function and antioxidant protection. These ingredients contribute to general cellular health and metabolic processes. Due to the very low evidence coverage, the overall clinical support for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Safety Alerts

⚠️ Niacin: 86mg is 2.5× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Packet(s) Serving Size

30 Servings

Other Combinations Product Type

51% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 Calorie(s)

Total Fat

1 Gram(s) (1% DV)

Cholesterol

5 mg (2% DV)

Vitamin A

3750 mcg (417% DV)

Vitamin C

30 mg (33% DV)

Vitamin D

10 mcg (50% DV)

✅ Within RDA (0.7× RDA of 0.015 mg) 📚 608 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.01mg UL 0.1mg

Vitamin E

134 mg (893% DV)

📊 8.9× RDA — above typical dose (UL: 1000 mg) 📚 179 studies (Tier A: 3, B: 90)

RDA 15mg This product: 134mg UL 1000mg

Thiamine

50 mg (4167% DV)

📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 50mg

Riboflavin

34.7 mg (2669% DV)

📊 26.7× RDA — above typical dose 📚 13 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 34.7mg

Niacin

86 mg (538% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 2.5× (UL: 35 mg) 📚 196 studies (Tier A: 5, B: 63)

RDA 14mg This product: 86mg UL 35mg

Vitamin B6

20.9 mg (1229% DV)

📊 16.1× RDA — above typical dose (UL: 100 mg) 📚 114 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 20.9mg UL 100mg

Folate

667 mcg DFE (167% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 226 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 667mg UL 1.0mg

Vitamin B12

500 mcg (20833% DV)

📊 208.3× RDA — above typical dose 📚 139 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.5mg

Biotin

400 mcg (1333% DV)

📊 13.3× RDA — above typical dose 📚 27 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.4mg

Pantothenic Acid

200 mg (4000% DV)

📊 40.0× RDA — above typical dose 📚 2 studies — no high-quality reviews

RDA 5mg This product: 200mg

Calcium

150 mg (12% DV)

Magnesium

100 mg (24% DV)

✅ Within RDA (0.2× RDA of 420 mg) 📚 316 studies (Tier A: 8, B: 159)

RDA 420mg This product: 100mg UL 350mg

Zinc

12.5 mg (114% DV)

✅ 1.1× RDA — within safe limits 📚 263 studies (Tier A: 6, B: 134)

RDA 11mg This product: 12.5mg UL 40mg

Selenium

100 mcg (182% DV)

✅ 1.8× RDA — within safe limits 📚 173 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.1mg UL 0.4mg

Copper

1 mg (111% DV)

✅ 1.1× RDA — within safe limits 📚 37 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 1mg UL 10mg

Manganese

2.5 mg (109% DV)

✅ 1.1× RDA — within safe limits 📚 9 studies — no high-quality reviews

RDA 2.3mg This product: 2.5mg UL 11mg

Chromium

250 mcg (714% DV)

📊 7.1× RDA — above typical dose 📚 199 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.25mg

Molybdenum

50 mcg (111% DV)

✅ 1.1× RDA — within safe limits 📚 3 studies — no high-quality reviews

RDA 0.045mg This product: 0.05mg UL 2mg

Potassium

50 mg (1% DV)

Boron Glycinate

1 mg

📊 Market median: 3.0mg (58 products) 📚 3 studies — no high-quality reviews

This product: 1mg UL 20mg

Vanadium

100 mcg

📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.1mg UL 1.8mg

Proprietary Mixed Carotenoid Blend

722 mcg

Coenzyme Q10

25 mg

📊 Market median: 100.0mg (283 products) 📚 144 studies (Tier A: 1, B: 64)

This product: 25mg UL 1200mg

Hawthorn (Crataegus spp.) extract

50 mg

📊 Market median: 333.0mg (166 products) 📚 9 studies (Tier A: 0, B: 2)

This product: 50mg

Ginger (Zingiber officinale) extract

50 mg

📊 Market median: 250.0mg (337 products) 📚 127 studies (Tier A: 1, B: 41)

This product: 50mg

Setria Glutathione

25 mg

Alpha Lipoic Acid

150 mg

📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews

This product: 150mg

N-Acetyl-L-Cysteine

700 mg

Milk Thistle (Silybum marianum) extract

175 mg

📊 Market median: 250.0mg (562 products) 📚 55 studies (Tier A: 0, B: 19)

This product: 175mg

Turmeric (Curcuma longa) extract

200 mg

📊 Market median: 450.0mg (254 products) 📚 243 studies (Tier A: 0, B: 100)

This product: 200mg

Broccoli (Brassica oleracea italica) sprout concentrate

100 mg

Artichoke (Cynara scolymus) extract

125 mg

Taurine

1225 mg

📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)

This product: 1225mg

Glycine

225 mg

L-Glutamine

225 mg

📊 Market median: 420.0mg (227 products)

Median 420.0mg This product: 225mg

L-Methionine

100 mg

📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews

This product: 100mg

Chlorella (Chlorella spp.) powder

200 mg

📊 Market median: 4.0mg (67 products)

Median 4.0mg This product: 200mg

Fish Oil concentrate

1000 mg

📊 Market median: 750.0mg (447 products) 📚 393 studies (Tier A: 18, B: 204)

This product: 1000mg UL 3000mg

Other Ingredients

Vegetarian Capsule Gelatin Capsule

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommendations: As a dietary supplement, take 1 packet daily (8 capsules), with a meal.

Recommendations: As a dietary supplement, take 1 packet daily (8 capsules), with a meal for gentle, daily detoxification support.

⚠️ Warnings & Precautions

Contains fish (anchovies, sardines, mackerel)

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

This product was sealed for your protection. Do not use if box or contents are open or damaged.

🧪 Formulation Notes

Comprehensive daily packet providing core nutrients, fish oil, taurine, NAC, milk thistle and chlorella to support healthy detoxification

With Metafolin L-5-MTHF

Gluten-free & non-GMO

ChromeMate KanekaQ10

Each packet contains UltraNutrient/3 vegetarian capsules EPA/DHA essentials/1 softgel capsule Liver-G.I. Detox/2 vegetarian capsules NAC (N-Acetyl-L-Cysteine)/1 vegetarian capsule Taurine/1 vegetarian capsule

Additional Information

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

Product Details

UPC / SKU 7 66298 01463 0

DSLD Entry Date 2021-03-25

Product Type Other Combinations

Form Capsule

Brand Pure Encapsulations

DSLD ID 246080

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →