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Energy And Metabolism

product on market Other (e.g. tea bag) GNC Women's Ultra Mega Safety: 99/100
99/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 66% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains essential vitamins A, C, D, E, and K, which support immune function, bone health, and antioxidant activity. There is strong research evidence supporting the roles of these nutrients in maintaining general metabolic health. The formulation maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Energy And Metabolism
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
45
Servings
Other Combinations
Product Type
66%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
200 mg (333% DV)
1600 IU (400% DV)
2.7× RDA — within safe limits 608 studies (A:16, B:251)
30 IU (100% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
80 mcg (100% DV)
Within RDA (0.7× RDA) 275 studies (A:9, B:175)
50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (2941% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
50 mcg (833% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
500 mg (50% DV)
Iron
18 mg (100% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
100 mg (25% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
15 mg (100% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (286% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
2 mg (100% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
120 mcg (100% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (100% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
Energy & Metabolism Blend
119 mg
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
10 mg
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
10 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
4 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
2 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
950 mcg
Market median: 10.0mg (35 products) 6 studies (A:0, B:2)
190 mcg
Market median: 4.0mg (32 products)
50 mcg
Market median: 4.0mg (47 products)
10 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)

Other Ingredients

Cellulose Titanium Dioxide natural Vanilla flavor Vegetable Acetoglycerides Riboflavin Sucralose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Approved Health
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take two caplets daily with food.

Warnings & Precautions

CONTAINS: Fish and Soybeans.

KEEP OUT OF REACH OF CHILDREN.

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

WARNING: Consult your physician prior to using this product it you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

Formulation Notes

Each serving supplies approximately 100 mg of caffeine.

No Artificial Colors, No Artificial Flavors, No Wheat, No Gluten, No Dairy, Yeast Free.

Additional Information

GNC QUALITY COMMITMENT GNC, the leader in the development and manufacture of dietary supplements, is committed to producing the highest quality products available. This commitment begins with quality designed supplement formulations. Every raw material that goes into a GNC supplement is guaranteed as to quality and potency. Each product is dated and then shipped immediately to our stores, so you can be sure you are purchasing the freshest supplements available. At GNC, we extend our quality commitment to you by offering our money-back guarantee.

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blend in this product for six weeks experienced statistically significant improvements in markers of B vitamin and antioxidant status, as well as improvements in SF-36 Vitality and Mental Health scores compared to those taking a placebo.

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Timed-Release

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- With 1,600 IU of vitamin D-3 for breast and bone health - Calorie burning support - Boosts energy and metabolism - Supports mental focus

Store in a cool, dry place.

•With 1600 IU of vitamin D-3 for breast & bone health •Calorie burning support •Boosts energy and metabolism •Supports mental focus

2X MORE D-3

ACTUAL SIZE

CLINICALLY STUDIED

CODE 178912 ILG

Compared to leading brands.

Conforms to USP <2091> for weight.

Energy

GNC GUARANTEE Use any GNC supplement for as little as 10 days. If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!

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Metadata

Product Details

DSLD Entry Date2012-08-24
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandGNC Women's Ultra Mega
DSLD ID12031
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.