🟢 99/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 62% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label Data

2 Orange Caplet(s) Serving Size
Other Combinations Product Type
62% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
200 mg (333% DV)
1600 IU (400% DV)
✅ 2.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.04mg UL 0.1mg
30 IU (100% DV)
✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 20.1mg UL 1000mg
80 mcg (100% DV)
✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.08mg
50 mg (3333% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
50 mg (2500% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
50 mcg (833% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
300 mcg (100% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
50 mg (500% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
Calcium
500 mg (50% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
100 mg (25% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
15 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
200 mcg (286% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
2 mg (100% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
120 mcg (100% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
75 mcg (100% DV)
✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.075mg UL 2mg
72 mg (2% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 72mg
Potassium
80 mg (2% DV)
Performance, Energy & Metabolism Blend (Combination)
100 mg
Joint Cushion Support Blend (Combination)
50 mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 25mg
10 mg
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 10mg UL 3500mg
10 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 10mg
Cranberry concentrate
10 mg
4 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 4mg
2 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 2mg UL 20mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.95mg
950 mcg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 0.95mg
190 mcg
📊 Market median: 4.0mg (32 products)
This product: 0.19mg
50 mcg
📊 Market median: 4.0mg (47 products)
This product: 0.05mg
10 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.01mg UL 1.8mg

Other Ingredients

Cellulose Titanium Dioxide natural Vanilla flavor Riboflavin Glycerol Esters Sucralose Carmine color

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (71% of products) Nutrient (61% of products) Approved Health (1% of products)

Target Groups

Adult Female (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take the contents of one pack daily with food.

To ensure a complete nutritional program, take daily with these GNC products: - Ultra Probiotic Complex - Triple Strength Fish Oil - SuperFoods Supreme - Protein

⚠️ Warnings & Precautions

Contains: Fish and Soybeans.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Keep out of the reach of children.

🧪 Formulation Notes

The Women's Ultra Mega Active Vitapak Program provides 1,100 mg calcium and 2,000 IU vitamin D-3.

Contains: Fish and Soybeans.

No Wheat, no Gluten, no Dairy, Yeast free.

- Clinically studied multivitamin featuring an advanced performance, energy and metabolism blend - Joint cushioning blend featuring vitamin C, collagen and hyaluronic acid

GNC Women's Ultra Mega Active Vitapak Program conveniently combines nutrients that support a woman's overall nutritional needs with focused ingredients to promote optimal health, joint cushioning and athletic performance.

Women's Ultra Mega Active contains 1,600 IU of vitamin D-3 for breast and bone health and immune support, as well as B vitamins that are important for carbohydrate metabolism and energy production. It's enhanced with 500 mg of bone-strengthening calcium and joint cushioning blend, with vitamin C, collagen and hyaluronic acid. It also combines a broad spectrum of cell-protecting antioxidant nutrients that also support immune health with key electrolytes that help regulate body fluids.

Additional Information

Conforms to USP <2091> for weight.

Each pack contains: Women's Ultra Mega Active Without Iron

This product is endorsed by the GNC Medical Advisory Board. This team of esteemed physicians utilizes their extensive medical knowledge and experience to aid in the creation of GNC premium products, helping you to achieve optimal health through comprehensive nutritional support so you can live your best life! In a randomized, double-blind placebo controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blend in this product for six weeks experienced statistically significant improvements in markers of B vitamin and antioxidant status, as well as improvements in SF-36 Vitality and Mental Health scores compared to those taking a placebo.

Code 329211 BPG

GNC quality commitment For more than 78 years, GNC has been the leader in the development of superior nutritional supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality controls. GNC guarantee If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you live well.

Store in a cool, dry place.

Physician endorsed

Women's Ultra Mega Active without Iron Our premium, time-release, clinically studied formula includes vitamins and minerals to supplement key nutrients that may be missing in your daily diet.

Product Details

DSLD Entry Date 2016-11-21
Product Type Other Combinations
Form Other (e.g. tea bag)
Bundle Active
DSLD ID 65939
Data Updated 2026-04-11

Research Evidence

566 Research Sources
56 Avg Quality Score
240 Meta Analysis
100 Clinical Trial
74 Systematic Review
71 Guideline
58 Rct
11 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
1 Observational
1 Openfda Safety
A Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency
Meta Analysis Nature medicine 2025
A Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Meta Analysis The Cochrane database of systematic reviews 2014
A Serum or plasma ferritin concentration as an index of iron deficiency and overload
Meta Analysis The Cochrane database of systematic reviews 2021
A Non-invasive diagnostic tests for Helicobacter pylori infection
Meta Analysis The Cochrane database of systematic reviews 2018
A Hypoxia-inducible factor stabilisers for the anaemia of chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2022
A Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations
Meta Analysis The Cochrane database of systematic reviews 2021
A Fortification of condiments and seasonings with iron for preventing anaemia and improving health
Meta Analysis The Cochrane database of systematic reviews 2023
A Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2024
A Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review
Meta Analysis Neuroscience and biobehavioral reviews 2025
View all evidence for Iron →

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