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Multivitamin Energy & Metabolism

product on market Other (e.g. tea bag) GNC Women's Safety: 98/100
98/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 60% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The formulation contains essential vitamins A, C, D, E, and K, which are supported by strong evidence for maintaining immune function and bone health. These nutrients play critical roles in cellular protection and metabolic processes. The product maintains a high safety profile with minimal reported concerns.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Multivitamin Energy & Metabolism
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
45
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
1500 mcg RAE (167% DV)
Vitamin C
300 mg (333% DV)
50 mcg (250% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
20.1 mg (134% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
80 mcg (67% DV)
Within RDA (0.7× RDA) 275 studies (A:9, B:175)
50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (3846% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2941% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
680 mcg DFE (170% DV)
Exceeds UL by 680.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
50 mcg (2083% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
10 mg (2% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
Calcium
300 mg (23% DV)
Iron
18 mg (100% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
100 mg (24% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
25 mg (227% DV)
2.3× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (364% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
2 mg (222% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (87% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
120 mcg (343% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (167% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
Coffee Bean Extract
102 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
Cayenne Fruit Extract
10 mg
10 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 100.0mg (173 products)
4 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
Black Pepper Fruit Extract
2.6 mg
2 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
2 mg
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
1 mg
Market median: 10.0mg (35 products) 6 studies (A:0, B:2)
400 mcg
Market median: 4.0mg (32 products)
50 mcg
Market median: 4.0mg (47 products)
10 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)

Other Ingredients

Cellulose Corn Starch Stearic Acid Magnesium Stearate Polyvinyl Alcohol Polyethylene Glycol Titanium Dioxide Talc Spirulina Extract Riboflavin Vanilla Mint Flavor, Natural Steviol Glycosides
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take two caplets daily with food. Do not take near bedtime.

Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Contains: soybeans, fish (anchovy, mackerel, sardine, smelt, whiting, pollock, salmon, tuna, cod or a combination thereof). Contains a bioengineered food ingredient.

Consult your physician prior to use if you are pregnant, nursing, taking medication or have a medical condition.

Keep out of reach of children.

Formulation Notes

Contains 100 mg of caffeine.

No artificial flavors, gluten free, no milk. Gf Gluten free

Energy & Metabolism Specially formulated for calorie burn & focus Timed-release

Warning: Cancer and reproductive harm – www.P65Warnings.ca.gov. Discontinue use two weeks prior to surgery. Inform your physician of this product’s biotin content before any lab test. Niacin may cause a temporary flushing reaction.

Additional Information

For more information: 1-888-462-2548 GNC.com

90 caplets/45-day supply

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 48107 24983 0
DSLD Entry Date2025-06-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandGNC Women's
DSLD ID331484
Data Updated2026-04-11
Research

Research Evidence

253
Research Sources
55
Avg Quality
128
Meta Analysis
52
Systematic Review
41
Rct
24
Clinical Trial
3
Regulatory Source
1
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021 PubMed DOI
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022 PubMed DOI
View all evidence for Vitamin E →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.