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One Daily Multi

product on market Other (e.g. tea bag) GNC Mega Men Safety: 99/100
99/100

This product looks safe

  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 69% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The formulation contains essential vitamins A, C, D, E, and K, which are supported by strong evidence for maintaining immune function and bone health. These nutrients play critical roles in cellular protection and metabolic processes. The ingredient profile demonstrates a high safety score with minimal risk for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for One Daily Multi
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
60
Servings
Other Combinations
Product Type
69%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
1050 mcg RAE (117% DV)
Vitamin C
100 mg (111% DV)
30 mcg (150% DV)
2.0× RDA — within safe limits 608 studies (A:16, B:251)
30.2 mg (201% DV)
2.0× RDA — within safe limits 179 studies (A:3, B:90)
80 mcg (67% DV)
Within RDA (0.7× RDA) 275 studies (A:9, B:175)
1.65 mg (138% DV)
1.4× RDA — within safe limits 76 studies (A:0, B:33)
1.87 mg (144% DV)
1.4× RDA — within safe limits 13 studies (A:0, B:1)
20 mg (125% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
3.3 mg (194% DV)
2.5× RDA — within safe limits 114 studies (A:3, B:35)
680 mcg DFE (170% DV)
Exceeds UL by 680.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
25 mcg (1042% DV)
10.4× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
16.5 mg (330% DV)
3.3× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
250 mg (19% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
125 mg (30% DV)
Within RDA (0.3× RDA) 316 studies (A:8, B:159)
30 mg (273% DV)
2.7× RDA — within safe limits 263 studies (A:6, B:134)
120 mcg (218% DV)
2.2× RDA — within safe limits 173 studies (A:0, B:67)
2 mg (222% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (87% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
200 mcg (571% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (167% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
70 mg (3% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Potassium
80 mg (2% DV)
5 mg
Market median: 420.0mg (227 products)
5 mg
Market median: 500.0mg (193 products) 7 studies — no high-quality reviews
5 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
5 mg
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
2.5 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
2 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
1 mg
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
600 mcg
Market median: 10.0mg (35 products) 6 studies (A:0, B:2)
200 mcg
Market median: 4.0mg (32 products)
150 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
10 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)

Other Ingredients

Microcrystalline Cellulose Maltodextrin Hydroxypropyl Methylcellulose Caramel color Choline Bitartrate Corn Starch Croscarmellose Sodium Ethyl Cellulose Glucose Syrup Gum Arabic Hydroxypropyl Cellulose Magnesium Stearate Mixed Tocopherols Food Starch, Modified natural Vanilla flavor Polyethylene Glycol Sodium Ascorbate Sodium Sulfate Stearic Acid Stevia Leaf Extract Sugar Talc Titanium Dioxide Tricalcium Phosphate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one caplet daily with food.

Warnings & Precautions

Warning: Cancer and reproductive harm - www.P65Warnings.ca.gov.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication or have a medical condition.

Discontinue use two weeks prior to surgery. Inform your physician of this product's biotin content before any lab test. Niacin may cause a temporary flushing reaction.

Keep out of reach of children.

Contains: Soy. Contains a bioengineered food ingredient.

Formulation Notes

No artificial flavors, gluten free.

Supports men's health

Supports men's health Fuels muscle performance Includes support for immune & brain health

Additional Information

Store in a cool, dry place.

For more information: 1-888-462-2548 GNC.com

Essentials

60-day supply

Metadata

Product Details

UPC / SKU0 48107 12037 5
DSLD Entry Date2024-04-23
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID304647
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.