Wellness Essentials Brain Health

product on market Other (e.g. tea bag) Metagenics 🟢 Safety: 89/100
Brand: Metagenics
🟢 89/100

This product is generally safe

  • Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 64% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Packet(s) Serving Size
30 Servings
Other Combinations Product Type
64% Evidence Coverage

Supplement Facts — Evidence Check

Calories
15 Calorie(s)
Total Fat
1.5 Gram(s) (2% DV)
Polyunsaturated Fat
1 Gram(s)
Total Carbohydrates
1 Gram(s) (1% DV)
Dietary Fiber
1 Gram(s) (4% DV)
Vitamin A
1500 mcg (167% DV)
Vitamin C
60 mg (67% DV)
12.5 mcg (63% DV)
✅ Within RDA (0.8× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0125mg UL 0.1mg
100.5 mg (670% DV)
📊 6.7× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 100.5mg UL 1000mg
60 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.06mg
12.5 mg (1042% DV)
📊 10.4× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 12.5mg
7.5 mg (577% DV)
📊 5.8× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 7.5mg
25 mg (156% DV)
✅ 1.8× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 25mg UL 35mg
12.5 mg (735% DV)
📊 9.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 12.5mg UL 100mg
665 mcg DFE (166% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 665.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 665mg UL 1.0mg
100 mcg (4167% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
250 mcg (833% DV)
📊 8.3× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.25mg
37.5 mg (750% DV)
📊 7.5× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 37.5mg
12.5 mg (2% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 12.5mg UL 3500mg
75 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.075mg UL 1.1mg
115 mg (27% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 115mg
16.5 mg (150% DV)
✅ 1.5× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 16.5mg UL 40mg
50 mcg (91% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
0.5 mg (56% DV)
✅ Within RDA (0.6× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.5mg UL 10mg
0.25 mg (11% DV)
✅ Within RDA (0.1× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 0.25mg UL 11mg
100 mcg (286% DV)
✅ 2.9× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.1mg
25 mcg (56% DV)
✅ Within RDA (0.6× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.025mg UL 2mg
1.3 Gram(s)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 1.3mg
Marine Lipid concentrate
1.3 Gram(s)
750 mg
📊 Market median: 750.0mg (447 products) 📚 388 studies (Tier A: 18, B: 204)
This product: 750mg UL 3000mg
250 mg
📊 Market median: 750.0mg (447 products) 📚 388 studies (Tier A: 18, B: 204)
This product: 250mg UL 3000mg
600 mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 600mg
Proprietary Phytonutrient Blend
200 mg
100 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 100mg UL 1200mg
12.5 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 12.5mg
5 mg
📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)
This product: 5mg
3 mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 3mg
3 mg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 3mg
1 mg
📊 Market median: 4.0mg (32 products)
This product: 1mg

Other Ingredients

PhytoMulti: Other Ingredients OmegaGenics Neuro 1000 Softgel Meta Lipoate 300: Other Ingredients Mag L-Threonate: Other Ingredients CoQ10 ST-100: Other Ingredients

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (86% of products) Nutrient (79% of products) Qualified Health (13% of products) Approved Health (2% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take one packet daily with food or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: This product contains calamari, a mollusk shellfish. Please note that a subset of individuals with crustacean allergies may also react to mollusks

Caution: Do not use if pregnant or nursing. Consult your healthcare practitioner if taking other nutritional supplements or medications.

Keep out of the reach of children.

Contains: Fish (anchovy, sardine, and mackerel).

🧪 Formulation Notes

Provides comprehensive support for cognitive function and brain health Wellness Essentials Brain Health is formulated to target your unique nutritional needs to support brain health and overall wellness.

Each once-daily packet provides: Multifaceted health support: PhytoMulti features a proprietary blend of 13 concentrated extracts and phytonutrients with scientifically tested biological activity to support cellular health and overall wellness. Cognitive health support: Features Magnesium L-Threonate, designed to support cognitive health. Magnesium, a divalent cation, is important for neuronal activity as it binds to neurotransmitter receptors and is a co-factor for neuronal enzymes. Mitochondrial function support: CoQ10 is essential for energy production by supporting mitochondrial function. Antioxidant activity and glucose metabolism support: Features Meta-Lipoate 300, a high quality alpha-lipoic acid which may protect tissues from free radicals, as well as support healthy glucose metabolism and cellular health. Cognitive and eye health: OmegaGenics Neuro 1000 features a concentrated, purified source of omega-3 fatty acids with 750mg DHA and 250mg EPA per softgel.

The wellness essential difference Overall wellness support Targeted health support Convenient and easy

The Metagenics difference Metagenics is a professional nutraceutical company that formulates, manufactures, and continually evaluates nutritional products in clinical practice. Each Wellness Essentials formula represents years of collective research to deliver optimized foundation nutrition and targeted health support.

Products included are gluten-free.

Wellness Essentials Brain Health helps provide advanced nutritional support for: Cognitive function Mitochondrial function Eye health Cellular health Healthy glucose-metabolism Nervous system function Cellular health General wellness Healthy aging

Featuring Magtein

Contains: Fish (anchovy, sardine, and mackerel).

Additional Information

Each Packet Contains: 1 PhytoMulti tablet (green), 1 OmegaGenics Neuro 1000 softgel (golden yellow), 2 Meta Lipoate 300 tablets (off-white with yellow speckles), 2 Mag L-Threonate capsules (white), and 1 CoQ10 ST-100 softgel (mustard yellow).

Storage: Keep in a cool, dry place.

Practitioner exclusive

Product Details

DSLD Entry Date 2020-02-26
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand Metagenics
DSLD ID 211103
Data Updated 2026-04-11

Research Evidence

495 Research Sources
56 Avg Quality Score
222 Meta Analysis
104 Clinical Trial
72 Rct
69 Systematic Review
11 Guideline
5 Cochrane Review
5 Regulatory Source
3 Narrative Review
1 Openfda Safety
A Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI Cochrane
A Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
A Omega-3 fatty acid addition during pregnancy
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI Cochrane
A Omega-3 fatty acids for depression in adults
Systematic Review The Cochrane database of systematic reviews 2021
PubMed DOI Cochrane
A Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI
A Non-immunosuppressive treatment for IgA nephropathy
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI
A Omega-3 fatty acid supplementation for depression in children and adolescents
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI Cochrane
A Interventions for fatigue and weight loss in adults with advanced progressive illness
Meta Analysis The Cochrane database of systematic reviews 2012
PubMed DOI
A Motor control exercise for chronic non-specific low-back pain
Meta Analysis The Cochrane database of systematic reviews 2016
PubMed DOI
A Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI
View all evidence for Omega 3 →

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