Mega Men 50 Plus by GNC Mega Men — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
65% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label Data

2 Beige Caplet(s) Serving Size

37 Servings

Other Combinations Product Type

65% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

5000 IU (100% DV)

Vitamin C

300 mg (500% DV)

Vitamin D

1600 IU (400% DV)

✅ 2.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.04mg UL 0.1mg

Vitamin E

30 IU (100% DV)

✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 20.1mg UL 1000mg

Vitamin K

80 mcg (100% DV)

✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.08mg

Thiamine

50 mg (3333% DV)

📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 50mg

Riboflavin

50 mg (2941% DV)

📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 50mg

Niacin

50 mg (250% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 50mg UL 35mg

Vitamin B6

50 mg (2500% DV)

📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 50mg UL 100mg

Folic Acid

400 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.4mg UL 1.0mg

Vitamin B12

50 mcg (833% DV)

📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.05mg

Biotin

300 mcg (100% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

50 mg (500% DV)

📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 50mg

Calcium

200 mg (20% DV)

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

100 mg (25% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 100mg

Zinc

25 mg (167% DV)

✅ 2.3× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 25mg UL 40mg

Selenium

200 mcg (286% DV)

📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.2mg UL 0.4mg

Copper

2 mg (100% DV)

✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 2mg UL 10mg

Manganese

2 mg (100% DV)

✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2mg UL 11mg

Chromium

120 mcg (100% DV)

📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.12mg

Molybdenum

75 mcg (100% DV)

✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.075mg UL 2mg

Saw Palmetto berries extract

160 mcg

📊 Market median: 320.0mg (426 products) 📚 24 studies (Tier A: 0, B: 5)

This product: 0.16mg

L-Arginine

100 mg

📊 Market median: 500.0mg (143 products)

This product: 100mg

Healthy Aging Free Radical Protection Blend

70 mg

Memory Health Blend

20 mg

Inositol

10 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 10mg

Silica

4 mg

📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)

This product: 4mg

Boron

2 mg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 2mg UL 20mg

Lutemax 2020 Lutein

950 mcg

📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.95mg

Lycopene

950 mcg

📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)

This product: 0.95mg

Zeaxanthin

190 mcg

📊 Market median: 4.0mg (32 products)

This product: 0.19mg

Astaxanthin

50 mcg

📊 Market median: 4.0mg (47 products)

This product: 0.05mg

Vanadium

10 mcg

📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.01mg UL 1.8mg

Other Ingredients

Cellulose Titanium Dioxide Vegetable Acetoglycerides Caramel color Ethyl Vanillin

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Seniors/Mature (>50 Years) - Men ONLY Gluten Free Dairy Free

Product Information

📋 Directions for Use

Scientific research shows that 400 mg per serving of free Phytosterols taken twice daily total of 800 mg, as part of a healthy diet low in saturated fat and cholesterol, may reduce the risk of heart disease. Each daily serving supplies 800 mg of Phytosterols.

DIRECTIONS: As a dietary supplement, take the contents of one pack daily with food.

Discontinue use two weeks prior to surgery.

⚠️ Warnings & Precautions

CONTAINS: Fish and Soybeans

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

KEEP OUT OF REACH OF CHILDREN

🧪 Formulation Notes

CONTAINS: Fish and Soybeans

Additional Information

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blend in this product for six weeks experienced statistically significant improvements in markers of B vitamin and antioxidants status, as well as improvements in SF-36 Vitality and Mental Health score compared to those taking a placebo.

CODE 328422 APG

Each Pack contains: Mega Men(R) 50 Plus Phytosterols Saw Palmetto Formula Fish Oil with CoQ-10 Memoral(R)

GNC QUALITY COMMITMENT For more than 77 years, GNC has been the leader in the development of superior nutritional supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality controls.

GNC GUARANTEE If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you LIVE WELL.

Clinically studied, no iron multivitamin with 1,600 IU of vitamin D-3

PHYSICIAN ENDORSED

50 Plus

BONUS SIZE-ONE EXTRA WEEK FREE!

Product Details

DSLD Entry Date 2014-05-23

Product Type Other Combinations

Form Other (e.g. tea bag)

Brand GNC Mega Men

Bundle 50 Plus

DSLD ID 33620

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →