🟢 99/100

This product looks safe

  • Vitamin B3: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 62% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vitamin B3: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label Data

4 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
62% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
20000 IU (400% DV)
Vitamin C
1000 mg (1667% DV)
1000 IU (250% DV)
✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.025mg UL 0.1mg
400 IU (1333% DV)
📊 17.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 268.0mg UL 1000mg
120 mcg (150% DV)
✅ Within RDA (1.0× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.12mg
50 mg (3333% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
100 mg (500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 100mg UL 35mg
100 mg (5000% DV)
📊 76.9× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 100mg UL 100mg
800 mcg (200% DV)
✅ 2.0× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.8mg UL 1.0mg
450 mcg (7500% DV)
📊 187.5× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.45mg
400 mcg (133% DV)
📊 13.3× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.4mg
300 mg (3000% DV)
📊 60.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 300mg
Calcium
500 mg (50% DV)
Iron
6 mg (33% DV)
75 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.075mg UL 1.1mg
500 mg (125% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 500mg
15 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
200 mcg (286% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
1.5 mg (5% DV)
✅ 1.7× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 1.5mg UL 10mg
5 mg (250% DV)
✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 5mg UL 11mg
200 mcg (167% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 200mg
50 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 50mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 50mg
50 mg
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 50mg UL 3500mg
Eleutherococcus senticosus
50 mg
50 mg
📊 Market median: 500.0mg (19 products)
This product: 50mg
📊 Market median: 500.0mg (9 products)
This product: 20mg
10 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 10mg
Papain
10 mg
📊 3.8× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 5mg
1 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 1mg UL 20mg
75 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.075mg UL 1.8mg

Other Ingredients

vegetarian capsule Vegetable Stearine

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested use for adults: 4-8 capsules daily, taken with meals, or as directed by your health care practitioner.

⚠️ Warnings & Precautions

Iron overdose usage: Keep this product out of the reach of children.

🧪 Formulation Notes

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

KARUNA(R) RESPONSIBLE NUTRITION(TM)

High Potency Multi-Vitamin and Mineral Formula with Bioflavonoids and Herbs

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place, tightly capped.

1102-LB8

Product Details

UPC / SKU 0 18647 01102 0
DSLD Entry Date 2013-08-23
Product Type Other Combinations
Form Capsule
Brand Karuna
DSLD ID 24512
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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