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EPD II Formula

product on market Tablet or Pill Douglas Laboratories Safety: 97/100
97/100

This product looks safe

  • Niacin/Niacinamide: 190mg is 5.4× the Tolerable Upper Intake Level (35mg)
  • Magnesium Complex: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)
  • Manganese: 20mg is 1.8× the Tolerable Upper Intake Level (11mg)
  • 53% of ingredients have research evidence
F Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains essential vitamins including A, C, D3, and B-complex vitamins, which have strong evidence for supporting immune function and cellular metabolism. Research indicates these nutrients are critical for maintaining vision, skin health, and energy production. The ingredient profile is supported by extensive clinical data regarding general nutritional maintenance.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin/Niacinamide: 190mg is 5.4× the Tolerable Upper Intake Level (35mg)

Magnesium Complex: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)

Manganese: 20mg is 1.8× the Tolerable Upper Intake Level (11mg)

Label

Product Label

Label for EPD II Formula
Open Full PDF View on NIH DSLD →
Details

Label Data

6 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
53%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
25000 IU (500% DV)
Vitamin C
300 mg (500% DV)
100 IU (25% DV)
Within RDA (0.2× RDA) 608 studies (A:16, B:251)
100 mg (6667% DV)
83.3× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (2941% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
190 mg (950% DV)
Exceeds UL by 5.4× (UL: 35 mg) 196 studies (A:5, B:63)
Vitamin B-6 Complex
100 mg (5000% DV)
800 mcg (200% DV)
2.0× RDA — within safe limits 226 studies (A:10, B:105)
500 mcg (8333% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
500 mg (5000% DV)
100.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
500 mg (50% DV)
200 mcg (133% DV)
1.3× RDA — within safe limits 245 studies (A:4, B:133)
500 mg (125% DV)
Exceeds UL by 1.4× (UL: 350 mg) 316 studies (A:8, B:159)
25 mg (167% DV)
2.3× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (286% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
2 mg (100% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
20 mg (1000% DV)
Exceeds UL by 1.8× (UL: 11 mg) 9 studies — no high-quality reviews
200 mcg (167% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)
300 mcg (400% DV)
6.7× RDA — above typical dose (UL: 2 mg) 3 studies — no high-quality reviews
Potassium
99 mg (2% DV)
60 mg
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
50 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
50 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)
1.5 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Trace Elements
100 mcg
L-Cysteine/N-Acetyl-L-Cysteine
200 mg
12.5 mg
Market median: 500.0mg (193 products) 7 studies — no high-quality reviews
Glutamic Acid
20 mg
114 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews

Other Ingredients

Cellulose Vegetable Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 6 tablets daily or as directed by physician. This product is best taken with meals.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Formulation Notes

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Formula #80497

Metadata

Product Details

UPC / SKU3 10539 01726 5
DSLD Entry Date2012-06-01
Product TypeOther Combinations
FormTablet or Pill
DSLD ID9874
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
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A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.