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Neuro-Natural Sleep

product on market Tablet or Pill Xtendlife Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 51% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The primary active ingredient is Vitamin B6, which plays a role in regulating sleep-wake cycles and neurotransmitter synthesis. Research evidence for this specific ingredient is moderate. Other listed components are basic macronutrients that do not have direct therapeutic effects on sleep.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Neuro-Natural Sleep
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Tablet(s)
Serving Size
15
Servings
Other Combinations
Product Type
51%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
20 Calorie(s)
Total Fat
0.5 Gram(s) (1% DV)
Total Carbohydrates
2 Gram(s) (1% DV)
Protein
1 Gram(s) (2% DV)
10 mg (500% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
323 mcg (81% DV)
Within RDA (0.8× RDA) 226 studies (A:10, B:105)
2005 mcg (668% DV)
66.8× RDA — above typical dose 27 studies (A:0, B:11)
90 mcg (129% DV)
1.6× RDA — within safe limits 173 studies (A:0, B:67)
Hop cone powder
500 mcg
Market median: 250.0mg (60 products) 7 studies (A:0, B:1)
L-Threonine
350 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
Bacopa leaf extract
250 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
160 mg
Market median: 60.0mg (94 products) 13 studies (A:0, B:7)
L-Carnosine
148 mg
Market median: 100.0mg (120 products)
Within RDA (0.2× RDA) 38 studies (A:1, B:7)
Market median: 300.0mg (159 products)
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
100 mg
Market median: 500.0mg (223 products) 24 studies (A:0, B:1)
98 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Market median: 250.0mg (182 products) 10 studies (A:0, B:2)
D-Phenylalanine
79 mg
73 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)
51 mg
Market median: 200.0mg (52 products) 12 studies (A:0, B:6)
Market median: 400.0mg (142 products) 10 studies (A:0, B:2)
Eleuthero root extract
50 mg
Market median: 333.0mg (166 products) 9 studies (A:0, B:2)
50 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Rosemary leaf extract
50 mg
L-Valine
50 mg
49 mg
Market median: 420.0mg (227 products)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
49 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
49 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Phosphatidyl Serine
20 mg
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
Vinpocetine
14 mg
Piperine
9 mg
200 mcg
Market median: 0.15mg (41 products)

Other Ingredients

Microcrystalline Cellulose Enteric Coating Dextrose Maltodextrin Silicon Dioxide Sodium Carboxymethyl Cellulose Magnesium Stearate Dicalcium Phosphate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions For Use Adults: 6 tablets per day. Age 12-18 Years: 3 tablets per day. Either take 6 tablets just before bedtime or split into 2 doses, before your evening meal and before bedtime.

Warnings & Precautions

Contains soy.

Formulation Notes

Contains soy.

Does not contain dairy, gluten, shellfish or peanut.

Additional Information

Store in a cool, dry place.

L1092-6

Best quality guarantee Advanced formula enteric coated

Made in New Zealand

Metadata

Product Details

DSLD Entry Date2017-12-22
Product TypeOther Combinations
FormTablet or Pill
DSLD ID82194
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.