Daily 1

product on market Tablet or Pill SuperSmart Safety: 99/100
99/100

This product looks safe

  • Vitamin B3: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains Nicotinamide Riboside and BioPQQ, which are studied for cellular energy and mitochondrial support. It also includes vitamins A, C, and D3, which have strong evidence for supporting immune function and overall health. Research on the synergistic effects of these specific combined ingredients remains limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin B3: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Daily 1
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

BioPQQ
5 mg
Within RDA (0.7× RDA) 196 studies (A:5, B:63)
Vitamin A
1000 mcg (125% DV)
Vitamin C
470 mg (587% DV)
50 mcg (1000% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
80 mg (665% DV)
5.3× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
75 mg (6800% DV)
62.5× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (3570% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (310% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (830% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
12.5 mg (890% DV)
9.6× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
500 mcg (250% DV)
1.2× RDA — within safe limits 226 studies (A:10, B:105)
400 mcg (16000% DV)
166.7× RDA — above typical dose 139 studies (A:1, B:44)
50 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
300 mcg (600% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
3 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
200 mcg (500% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
100 mg (26% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
100 mcg (200% DV)
2.2× RDA — within safe limits 3 studies — no high-quality reviews
150 mcg (270% DV)
2.7× RDA — within safe limits 173 studies (A:0, B:67)
15 mg (150% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
11 mg
Market median: 10.0mg (105 products) 2 studies (A:0, B:1)
10 mg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)
Apigenin
5 mg
Market median: 4.0mg (47 products)
1 mg
Market median: 10.0mg (35 products) 6 studies (A:0, B:2)

Other Ingredients

Calcium Carbonate Stearic Acid Maltodextrin Croscarmellose Sodium HPMC
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Take 1 tablet daily with a meal.

Warnings & Precautions

Precautions: Contains iodine and a soy derivative.

Do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used to replace a varied, balanced diet or healthy lifestyle. As with any dietary supplement, consult a healthcare professional before consuming if you have a health condition.

Directions: For adults only. Keep out of young children's reach.

Not recommended for pregnant or breastfeeding women.

Formulation Notes

BioPQQ, Mitsubishi, Japan

Metadata

Product Details

UPC / SKU5 453003 828068
DSLD Entry Date2025-09-25
Product TypeOther Combinations
FormTablet or Pill
DSLD ID339823
Data Updated2026-04-11
Research

Research Evidence

10
Research Sources
49
Avg Quality
8
Rct
1
Systematic Review
1
Clinical Trial
B Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Rct Nature communications 2018 PubMed DOI
C The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials
Systematic Review Frontiers in nutrition 2023 PubMed DOI
C Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.
Rct Nature aging PubMed DOI
C Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Rct Scientific reports 2019 PubMed DOI
C Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
Rct Cell reports 2019 PubMed DOI
C Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
Rct Aging cell 2023 PubMed DOI
C Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI
Rct BMC nephrology 2020 PubMed DOI
C Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
Clinical Trial ClinicalTrials.gov 2021
C A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.
Rct JCI insight PubMed DOI
C Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.
Rct Aging cell PubMed DOI
View all evidence for Nicotinamide Riboside →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.