🟢 98/100

This product looks safe

  • Niacin: 50.2mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 56% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50.2mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

168 Gram(s) Serving Size
8 Servings
Other Combinations Product Type
56% Evidence Coverage

Supplement Facts — Evidence Check

Calories
1250 Calorie(s)
Total Fat
4 Gram(s) (5% DV)
Cholesterol
95 mg (32% DV)
Protein
50 Gram(s) (100% DV)
Vitamin A
940 mcg (104% DV)
Vitamin C
60 mg (67% DV)
5 mcg (25% DV)
✅ Within RDA (0.3× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.005mg UL 0.1mg
20 mg (133% DV)
✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 20mg UL 1000mg
4.8 mg (400% DV)
📊 4.0× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 4.8mg
4 mg (308% DV)
📊 3.1× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 4mg
50.2 mg (314% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50.2mg UL 35mg
5 mg (294% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
680 mcg DFE (170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 680mg UL 1.0mg
11 mcg (458% DV)
📊 4.6× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.011mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
25 mg (500% DV)
📊 5.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 25mg
250 mg (45% DV)
✅ Within RDA (0.5× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 250mg UL 3500mg
Calcium
610 mg (47% DV)
Iron
9 mg (50% DV)
540 mg (43% DV)
✅ Within RDA (0.8× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 540mg UL 4000mg
53 mcg (35% DV)
✅ Within RDA (0.4× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.053mg UL 1.1mg
180 mg (43% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 180mg
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
71 mcg (129% DV)
✅ 1.3× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.071mg UL 0.4mg
1 mg (111% DV)
✅ 1.1× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 1mg UL 10mg
2.45 mg (107% DV)
✅ 1.1× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2.45mg UL 11mg
120 mcg (343% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
80 mcg (178% DV)
✅ 1.8× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.08mg UL 2mg
Sodium
690 mg (30% DV)
Potassium
1100 mg (23% DV)
📊 Market median: 5.0mg (298 products) 📚 701 studies (Tier A: 5, B: 123)
This product: 3mg
500 mg
📊 Market median: 420.0mg (227 products)
Median 420.0mg This product: 500mg
250 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 250mg
5 mg
📊 Market median: 500.0mg (9 products)
This product: 5mg

Other Ingredients

Maltodextrin Protein Blend Cocoa Natural and Artificial flavors Medium Chain Triglyceride Creamer Salt Sucralose Acesulfame Potassium

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

336 grams About 2 heaping scoops serious mass protein powder 24 fl oz Cold water, milk or other beverage 30-45 seconds Blend until dissolved Tips: New users may find it beneficial to begin with 1/2 of a serving daily for the first week and then gradually increase to 1 serving a day.

Suggested Use: For healthy adults, consume enough protein to meet your daily protein requirements with a combination of high protein foods and protein supplements throughout the day as part of a balanced diet and exercise program.

⚠️ Warnings & Precautions

Contains: Egg, milk, soy.

🧪 Formulation Notes

Why serious mass? Each serving is packed with 1,250 calories to support a calorie surplus for weight and muscle building. 50 grams of protein to support muscle building and recovery. 253 grams of carbohydrates to support fueling of intense workouts and aid in replenishment of glycogen stores. 3 grams of creatine monohydrate to support performance. 25 vitamins and minerals plus glutamine.

Strength training Supports performance Supports weight gain goals

Supports muscle building & weight gain goals

1250 calories Helps boost calorie intake 50 g protein Helps build and maintain muscle 253 g carbs Helps fuel intense workouts Chocolate peanut butter artificially flavored

Serious Mass is designed to provide serious calories, protein and carbohydrates – making this a convenient way to get extra calories throughout your day.

Additional Information

Optimum Nutrition has been trusted to provide the highest quality in post-workout recovery, pre-workout energy, and on-the-go sports nutrition for over 30 years and in 90+ countries. After careful supplier selection, each ingredient is tested to assure exceptional purity, potency and composition. We hold ourselves to the highest production standards, all so you can unlock your body’s full potential. Authentic Optimum Nutrition product Optimumnutrition.com/authentic

Informed Choice We test - you trust Informed Choice is a quality assurance program for sports nutrition products. The program certifies that nutritional supplements that bear the Informed Choice logo are regularly tested for banned substances by the world class sports anti-doping lab, LGC Limited. Manufactured in the USA This product contains ingredients of international and domestic origin

See supplement facts for sodium and cholesterol content When taken in addition to normal calorie intake and regular weight resistance training

Check out optimumnutrition.com for recipes and training tips.

Store in a cool, dry place.

Serving scoop included, but may settle to the bottom during shipping

Contents sold by weight not volume. Some settling will occur.

Product Details

UPC / SKU 7 48927 05143 8
DSLD Entry Date 2023-02-21
Product Type Other Combinations
Form Powder
DSLD ID 270149
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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