Wellness Essentials Women by Metagenics — Ingredients, Evidence & Safety

🟢 88/100

This product is generally safe

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
Folate: 1330mg is 1330.0× the Tolerable Upper Intake Level (1.0mg)
Contains proprietary blend — exact ingredient amounts not disclosed
60% of ingredients have research evidence

D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 1330mg is 1330.0× the Tolerable Upper Intake Level (1.0mg)

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Packet(s) Serving Size

30 Servings

Other Combinations Product Type

60% Evidence Coverage

Supplement Facts — Evidence Check

Calories

20 Calorie(s)

Total Fat

2 Gram(s) (3% DV)

Cholesterol

5 mg (2% DV)

Total Carbohydrates

1 Gram(s) (1% DV)

Vitamin A

3000 mcg (333% DV)

Vitamin C

120 mg (133% DV)

Vitamin D

25 mcg (125% DV)

✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.025mg UL 0.1mg

Vitamin E

67 mg (447% DV)

📊 4.5× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 67mg UL 1000mg

Vitamin K

120 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.12mg

Thiamine

25 mg (2083% DV)

📊 20.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 25mg

Riboflavin

15 mg (1154% DV)

📊 11.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 15mg

Niacin

50 mg (313% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 50mg UL 35mg

Vitamin B6

25 mg (1471% DV)

📊 19.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 25mg UL 100mg

Folate

1330 mcg DFE (333% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1330.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 1330mg UL 1.0mg

Vitamin B12

200 mcg (8333% DV)

📊 83.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.2mg

Biotin

500 mcg (1667% DV)

📊 16.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.5mg

Pantothenic Acid

75 mg (1500% DV)

📊 15.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 75mg

Choline

25 mg (5% DV)

📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 25mg UL 3500mg

Calcium

670 mg (52% DV)

Iron

18 mg (100% DV)

Phosphorus

340 mg (27% DV)

✅ Within RDA (0.5× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 340mg UL 4000mg

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

40 mg (10% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 40mg

Zinc

15 mg (136% DV)

✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 15mg UL 40mg

Selenium

100 mcg (182% DV)

✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.1mg UL 0.4mg

Copper

1 mg (111% DV)

✅ 1.1× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 1mg UL 10mg

Manganese

0.5 mg (22% DV)

✅ Within RDA (0.2× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 0.5mg UL 11mg

Chromium

200 mcg (571% DV)

📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.2mg

Molybdenum

50 mcg (111% DV)

✅ 1.1× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.05mg UL 2mg

Marine Lipid concentrate

2 Gram(s)

Microcrystalline Hydroxyapatite concentrate

2 Gram(s)

Proprietary Phytonutrient Blend

400 mg

Myo-Inositol

25 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 25mg

Resveratrol

10 mg

📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)

This product: 10mg

Lutein

6 mg

📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 6mg

Lycopene

6 mg

📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)

This product: 6mg

Zeaxanthin

2 mg

📊 Market median: 4.0mg (32 products)

This product: 2mg

Other Ingredients

PhytoMulti with Iron OmegaGenics EPA-DHA 500 Bone Builder Extra Strength

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult Female (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take one packet daily or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Excess vitamin A intake may increase the risk of birth defects. Pregnant women and women who may become pregnant should not exceed 3,000 mcg of preformed vitamin A (retinyl acetate) per day. Caution: Consult your healthcare practitioner if pregnant, nursing, or taking other nutritional supplements or medications.

Contains: Fish (sardine, anchovy, and mackerel).

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

🧪 Formulation Notes

Targeted support for women's health

Support heart health, bone health, and overall wellness daily. Wellness Essentials Women is formulated to target your unique nutritional needs to help you stay active and vital and maintain general health.

Each once-daily packet provides: Multifaceted health support: PhytoMulti with Iron is the “smart multi” with essential nutrients and a proprietary blend of 13 concentrated extracts and phytonutrients to help support cellular health and overall wellness. Bone density support: Bone Builder Extra Strength goes beyond calcium with purity-tested MCHC—a complex crystalline compound composed primarily of calcium, phosphorus, trace minerals, and bone growth factors to support bone health. Cardiovascular health support, immune system health support, and general wellness support: OmegaGenics EPA-DHA 500 is a quality-guaranteed omega-3 fatty acid formula manufactured and third-party tested to ensure safety and potency.

The wellness essentials difference Overall wellness support Targeted health support Convenient and easy

Products included are non-GMO and gluten-free.

Wellness Essentials Women provides Advanced Nutritional Support for: Vitality Heart health Bone health Brain health Nervous system health Eye health Immune system health Liver health Cellular health General health

Additional Information

The Metagenics difference Metagenics is a professional nutraceutical company that formulates, manufactures, and continually evaluates nutritional products in clinical practice. Each Wellness Essentials formula represents years of collective research to deliver optimized foundation nutrition and targeted health support.

GF Certified Gluten-free

Each packet contains: 2 PhytoMulti with Iron tablets (green), 2 OmegaGenics EPA-DHA 500 softgels (golden yellow), and 2 Bone Builder Extra strength tablets (white).

Storage: Keep in a cool, dry place.

Please recycle

Practitioner exclusive

Product Details

UPC / SKU 7 55571 92955 6

DSLD Entry Date 2020-03-24

Product Type Other Combinations

Form Other (e.g. tea bag)

Brand Metagenics

DSLD ID 216516

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →