🟢 89/100

This product is generally safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 66% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

2 Tablet(s) Serving Size
Other Combinations Product Type
66% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
200 mg (333% DV)
1600 IU (400% DV)
✅ 2.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.04mg UL 0.1mg
30 IU (100% DV)
✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 20.1mg UL 1000mg
80 mcg (100% DV)
✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.08mg
50 mg (3333% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
50 mg (2500% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
50 mcg (833% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
300 mcg (100% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
50 mg (500% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
Calcium
500 mg (50% DV)
100 mg (25% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
15 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
200 mcg (286% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
2 mg (100% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
120 mcg (100% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
75 mcg (100% DV)
✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.075mg UL 2mg
Proprietary Fruit & Vegetable Blend
105 mg
Proprietary Beauty Blend
100 mg
10 mg
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 10mg UL 3500mg
10 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 10mg
4 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 4mg
2 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 2mg UL 20mg
950 mcg
📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)
This product: 0.95mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.95mg
190 mcg
📊 Market median: 4.0mg (32 products)
This product: 0.19mg
50 mcg
📊 Market median: 4.0mg (47 products)
This product: 0.05mg
10 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.01mg UL 1.8mg

Other Ingredients

Cellulose Titanium Dioxide Vegetable Acetoglycerides natural Vanilla flavor Chlorophyll Sucralose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (74% of products) Nutrient (53% of products)

Target Groups

Adult Female (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take the contents of one pack daily with food.

⚠️ Warnings & Precautions

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

No Artificial Colors, No Artificial Flavors, No Wheat, No Gluten, No Dairy, Yeast Free.

CONTAINS: Fish and Soybeans.

Additional Information

GNC QUALITY COMMITMENT For more than 75 years, GNC has been the leader in the development and manufacture of dietary supplements and is committed to producing the most superior products. We use only the highest quality ingredients manufactured under the strictest quality controls. Every raw material used is tested to ensure its purity and potency. Each product is dated and shipped immediately to our stores to ensure that your are purchasing the freshest supplements available. GNC GUARANTEE If you are not 100% completely satisfied, return the unused portion of the product with your receipt to a GNC store within 30 days. Our trained sales staff will either refund your purchase price or, if you prefer, assist you in finding a replacement product to help you LIVE WELL.

^In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blend in this product for six weeks experienced statistically significant improvements in markers of B vitamin and antioxidant status, as well as improvements in SF-36 Vitality and Mental Health scores compared to those taking a placebo.

CODE 348311 DNG

Clinically proven multivitamin^ with 1,600 IU vitamin D-3 for breast and immune health*

CLINICALLY STUDIED^

Joint

Conforms to USP <2091> for weight.

ACTUAL SIZE

Store in a cool, dry place.

Lutemax(TM) 2020 LUTEIN & ZEAXANTHIN

To ensure a complete nutritional program, take daily with these GNC products: -Ultra Probiotic Complex 25 -CoQ-10 -SuperFoods Whole Foods Blend -GNC Protein

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Product Details

DSLD Entry Date 2013-03-25
Product Type Other Combinations
Form Tablet or Pill
Bundle Joint
DSLD ID 19458
Data Updated 2026-04-11

Research Evidence

292 Research Sources
57 Avg Quality Score
160 Meta Analysis
70 Systematic Review
36 Rct
8 Cochrane Review
8 Clinical Trial
3 Regulatory Source
2 Narrative Review
2 Other
1 Guideline
1 Openfda Safety
A Umbilical cord antiseptics for preventing sepsis and death among newborns
Meta Analysis The Cochrane database of systematic reviews 2026
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Interventions for cutaneous molluscum contagiosum
Meta Analysis The Cochrane database of systematic reviews 2017
A Chlorhexidine vs Povidone-Iodine and Incidence of Catheter-Related Infections: A Systematic Review and Meta-Analysis
Meta Analysis JAMA network open 2026
B Radioiodine Remnant Ablation for Differentiated Thyroid Cancer: A Systematic Review and Meta-analysis
Meta Analysis JAMA otolaryngology-- head & neck surgery 2021
B Risk of primary breast cancer in patients with differentiated thyroid cancer undergoing radioactive iodine therapy: a systematic review and meta-analysis
Meta Analysis European journal of nuclear medicine and molecular imaging 2022
B Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomised controlled trials
Meta Analysis The Lancet. Infectious diseases 2022
B Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
B Interventions for ingrowing toenails
Meta Analysis The Cochrane database of systematic reviews 2012
B Interventions for the management of malignant pleural effusions: a network meta-analysis
Systematic Review The Cochrane database of systematic reviews 2016
View all evidence for Iodine →

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