🟢 99/100

This product looks safe

  • Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • 66% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)

Label Data

1 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
66% Evidence Coverage

Supplement Facts — Evidence Check

Potassium
80 mg (2% DV)
Vitamin C
120 mg (200% DV)
Calcium
100 mg (10% DV)
Iron
18 mg (100% DV)
400 IU (100% DV)
✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.01mg UL 0.1mg
60 IU (200% DV)
✅ 2.7× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 40.2mg UL 1000mg
50 mcg (17% DV)
✅ 1.7× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.05mg
72 mg (2% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 72mg
120 mcg (100% DV)
📊 3.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.12mg
0.9 mg (45% DV)
✅ Within RDA (1.0× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.9mg UL 10mg
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
40 mg (10% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 40mg
4 mg (200% DV)
✅ 1.7× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 4mg UL 11mg
75 mcg (100% DV)
✅ 1.7× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.075mg UL 2mg
12 mg (120% DV)
✅ 2.4× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 12mg
48 mg (5% DV)
✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 48mg UL 4000mg
70 mcg (100% DV)
✅ 1.3× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.07mg UL 0.4mg
18 mcg (300% DV)
📊 7.5× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.018mg
6 mg (300% DV)
📊 4.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 6mg UL 100mg
11 mg (73% DV)
✅ Within RDA (1.0× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 11mg UL 40mg
60 mcg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 0.06mg UL 20mg
Nickel
5 mcg
4 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 4mg
Tin
10 mcg
10 mcg
📊 Market median: 0.5mg (6 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 0.01mg UL 1.8mg
5.1 mg (300% DV)
📊 3.9× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 5.1mg
4.5 mg (300% DV)
📊 3.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 4.5mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
Vitamin A
3500 IU (70% DV)
25 mcg (31% DV)
✅ Within RDA (0.2× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.025mg
40 mg (200% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 40mg UL 35mg
📊 Market median: 450.0mg (390 products) 📚 155 studies (Tier A: 0, B: 63)
This product: 50mg

Other Ingredients

Dicalcium Phosphate Potassium Chloride Ascorbic Acid Calcium Carbonate Microcrystalline Cellulose Magnesium Oxide DL-Alpha-Tocopheryl Acetate Gelatin Ferrous Fumarate Niacinamide Croscarmellose Sodium Maltodextrin Panax Ginseng Standardized Extract Stearic Acid Calcium Silicate Polyvinyl Alcohol Calcium Pantothenate Zinc Oxide Manganese Sulfate Silicon Dioxide Pyridoxine Hydrochloride Polyethylene Glycol Titanium Dioxide Magnesium Stearate Thiamine Mononitrate Riboflavin FD&C Yellow 6 Lake Talc Cupric Sulfate Vitamin A Acetate Chromium Picolinate Beta-Carotene Sodium Borate Folic Acid Sodium Molybdate Potassium Iodide Sodium Selenate Sodium Metasilicate Biotin Phytonadione Nickel Sulfate Sodium Metavanadate Stannous Chloride Cyanocobalamin Cholecalciferol

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions Adults - Take one tablet daily with food.

⚠️ Warnings & Precautions

Not formulated for use in children.

As with any supplement, if you are pregnant or nursing a baby, if you are taking medication, have a medical condition or are planning any medical procedure, ask a doctor before using this product.

Warnings Do not use if printed seal under cap is broken or missing.

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a Poison Control Center immediately.

Important Information: Long-term intake of high levels of vitamin A (excluding that sourced from betacarotene) may increase the risk of osteoporosis in adults. Do not take this product if taking other vitamin A supplements.

Additional Information

Store at room temperature. Keep bottle tightly closed.

Product Details

Compare to Centrum Performance ingredients (This product is not manufactured or distributed by Wyeth Consumer Healthcare, marketer of Centrum Performance). Helps support energy metabolism. B vitamins help convert food to fuel for the body. Formulated support for the active individual with the added benefits of a complete multivitamin (32 nutrients). Energy Metabolism: B vitamins help convert food to fuel for the body. Heart Health: Vitamins C, E B6, B12 & folic acid help support a healthy heart. Overall Health: Formulated with key nutrients to help meet daily nutritional needs. CVS quality. Please recycle.

Spectravite energy metabolism, advanced active formula, tablets

Product Details

UPC / SKU 0 50428 45578 4
DSLD Entry Date 2016-09-22
Product Type Other Combinations
Form Tablet or Pill
Brand CVS Pharmacy
DSLD ID 64337
Data Updated 2026-04-11

Research Evidence

849 Research Sources
56 Avg Quality Score
450 Meta Analysis
152 Rct
137 Systematic Review
73 Clinical Trial
11 Regulatory Source
7 Other
7 Guideline
3 Openfda Safety
2 Cochrane Review
2 Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021
View all evidence for Electrolytes →

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