🟢 98/100

This product looks safe

  • Vitamin D: 0.14mg is 1.4× the Tolerable Upper Intake Level (0.1mg)
  • Folate: 485mg is 485.0× the Tolerable Upper Intake Level (1.0mg)
  • 58% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vitamin D: 0.14mg is 1.4× the Tolerable Upper Intake Level (0.1mg)
⚠️ Folate: 485mg is 485.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

13.3 Gram(s) Serving Size
30 Servings
Other Combinations Product Type
58% Evidence Coverage

Supplement Facts — Evidence Check

Calories
25 Calorie(s)
Total Carbohydrates
6 Gram(s) (2% DV)
Vitamin A
1165 mcg RAE (129% DV)
Vitamin C
210 mg (233% DV)
140 mcg (700% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.14mg UL 0.1mg
21 mcg (140% DV)
📊 Market median: 80.0mg (1390 products) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 0.021mg UL 1000mg
45 mcg (38% DV)
✅ Within RDA (0.4× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.045mg
6.5 mg (542% DV)
📊 5.4× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 6.5mg
9.8 mg (754% DV)
📊 7.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 9.8mg
20 mg NE (125% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
22.8 mg (1341% DV)
📊 17.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 22.8mg UL 100mg
485 mcg DFE (121% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 485.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 485mg UL 1.0mg
11 mcg (458% DV)
📊 4.6× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.011mg
225 mcg (750% DV)
📊 7.5× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.225mg
12.5 mg (250% DV)
✅ 2.5× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 12.5mg
Calcium
130 mg (10% DV)
Iron
10 mg (56% DV)
100 mcg (67% DV)
✅ Within RDA (0.7× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.1mg UL 1.1mg
150 mg (36% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 150mg
11 mg (100% DV)
✅ Within RDA (1.0× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 11mg UL 40mg
20 mcg (36% DV)
✅ Within RDA (0.4× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.02mg UL 0.4mg
0.1 mg (11% DV)
✅ Within RDA (0.1× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.1mg UL 10mg
0.5 mg (22% DV)
✅ Within RDA (0.2× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 0.5mg UL 11mg
227.5 mcg (650% DV)
📊 6.5× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2275mg
25 mcg (56% DV)
✅ Within RDA (0.6× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.025mg UL 2mg
Sodium
45 mg (2% DV)
Potassium
390 mg (8% DV)
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 60mg UL 1200mg
20 mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 20mg
Lipase
5 mg
2 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 2mg UL 20mg

Other Ingredients

Fructose Citric Acid Malic Acid Maltodextrin Lemon Juice, Powder Orange Juice, Powder Silicon Dioxide Rebaudioside A natural & artificial Passion Fruit flavors Raspberry flavor Orange Flavor, Natural Natural and Artificial Mango Flavor Luo Han Guo fruit extract Lemon flavor Apple Fiber Beet, Powder Black Cherry flavor Glucose French Vanilla Flavor, Natural Stearic Acid Lime flavor

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions for use 1 Pour contents of packet into a cup 2 Add 8 fl oz of water into the cup and stir As a dietary supplement, take once daily or as directed by your healthcare provider. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amount of water and powder are used.

⚠️ Warnings & Precautions

If you are currently using Warfarin (Coumadin) or other blood-thinning, anti-platelet/anticoagulant medications, consult your healthcare provider before using this product. If you are currently using digoxin, diltiazem, calcipotriene or thiazide diuretics, do not use this product. If you are currently using any prescription drugs, have an ongoing medical condition or are pregnant or breastfeeding, consult your healthcare provider before using this product.

Certain medical conditions such as primary hyperparathyroidism, sarcoidosis, tuberculosis and lymphoma can increase the risk of hypercalcemia in response to Vitamin D. If you have any of these specific conditions, do not use this product. Do not use if packet has been opened.

Keep out of reach of children.

🧪 Formulation Notes

A custom formula designed for anti-aging.

Gluten free

This product contains no added wheat, soy, gluten, salt, preservatives or milk.

Cognitive health Antioxidant defense Skeletal & muscle health Do you want to keep feeling young? Ready to reclaim your youthful vigor? Isotonix Essentials Anti-Aging is a custom blend designed to restore the vitamins and minerals that deplete as your body ages. Our Anti-Aging formula helps support brain and cognitive health, provides a strong antioxidant defense and provides daily nutrients to support healthy aging.

Features a dynamic blend of antioxidants, botanicals and minerals.

Additional Information

30 - 0.47 oz (13.3 g) packets

Stroe in a cool, dry place.

Product Details

DSLD Entry Date 2024-07-25
Product Type Other Combinations
Form Powder
DSLD ID 313418
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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