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Polyphenol Nutrients

product on market Capsule Pure Encapsulations Safety: 88/100
88/100

This product is generally safe

  • Niacin: 37.5mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 58% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains essential vitamins that support immune function and cellular protection, with strong evidence for the roles of vitamins C and D. Thiamine and vitamin A contribute to metabolic and vision health. The overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 37.5mg is 1.1× the Tolerable Upper Intake Level (35mg)

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Polyphenol Nutrients
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
120
Servings
Other Combinations
Product Type
58%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
1125 mcg (125% DV)
Vitamin C
250 mg (278% DV)
10 mcg (50% DV)
Within RDA (0.7× RDA) 608 studies (A:16, B:251)
34 mg (223% DV)
2.3× RDA — within safe limits 179 studies (A:3, B:90)
25 mg (2083% DV)
20.8× RDA — above typical dose 76 studies (A:0, B:33)
17.35 mg (1335% DV)
13.3× RDA — above typical dose 13 studies (A:0, B:1)
37.5 mg (234% DV)
Exceeds UL by 1.1× (UL: 35 mg) 196 studies (A:5, B:63)
10.4 mg (612% DV)
8.0× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
667 mcg DFE (167% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
250 mcg (10417% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
400 mcg (1333% DV)
13.3× RDA — above typical dose 27 studies (A:0, B:11)
25 mg (500% DV)
5.0× RDA — above typical dose 2 studies — no high-quality reviews
20 mg (4% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
Calcium
150 mg (12% DV)
100 mcg (67% DV)
Within RDA (0.7× RDA) 245 studies (A:4, B:133)
75 mg (18% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
7.5 mg (68% DV)
Within RDA (0.7× RDA) 263 studies (A:6, B:134)
100 mcg (182% DV)
1.8× RDA — within safe limits 173 studies (A:0, B:67)
1 mg (111% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
2.5 mg (109% DV)
1.1× RDA — within safe limits 9 studies — no high-quality reviews
50 mcg (143% DV)
1.4× RDA — within safe limits 199 studies (A:1, B:55)
50 mcg (111% DV)
1.1× RDA — within safe limits 3 studies — no high-quality reviews
Potassium
49 mg (1% DV)
1 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
50 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)
Proprietary Mixed Carotenoid Blend
212 mcg
N-Acetyl-L-Cysteine
50 mg
50 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
MacularSynergy Complex
Cell Health Polyphenols

Other Ingredients

Vegetarian Capsule Ascorbyl Palmitate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: As a dietary supplement, take 3 capsules, 1-2 times daily, with meals.

Warnings & Precautions

Warning: Take with food. If you have liver problems, consult your health professional before use.

If pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Multivitamin/mineral formula with added polyphenols for advanced cellular protection

Gluten-free, non-GMO & hypoallergenic

Gluten-free, non-GMO & hypoallergenic

Additional Information

Store in a cool, dry place.

Scan to learn about our hypoallergenic supplements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

GFCO.org Certified Gluten-free by the Gluten-Free Certification Organization, www.gluten.org

Metadata

Product Details

UPC / SKU7 66298 00841 7
DSLD Entry Date2022-11-22
Product TypeOther Combinations
FormCapsule
BrandPure Encapsulations
DSLD ID278237
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.