Multigenics by Metagenics — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Niacin: 420mg is 12.0× the Tolerable Upper Intake Level (35mg)
64% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 420mg is 12.0× the Tolerable Upper Intake Level (35mg)

Label Data

6 Tablet(s) Serving Size

30 Servings

Other Combinations Product Type

64% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

10000 IU (200% DV)

Vitamin C

1200 mg (2000% DV)

Vitamin D

20 IU (5% DV)

📊 Market median: 0.03mg (3448 products) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.0005mg UL 0.1mg

Vitamin E

100 IU (333% DV)

📊 4.5× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 67.0mg UL 1000mg

Thiamine

30 mg (2000% DV)

📊 25.0× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 30mg

Riboflavin

34 mg (2000% DV)

📊 26.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 34mg

Niacin

420 mg (2100% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 12.0× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 420mg UL 35mg

Vitamin B6

40 mg (2000% DV)

📊 30.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 40mg UL 100mg

Folate

800 mcg (200% DV)

✅ 2.0× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.8mg UL 1.0mg

Vitamin B12

200 mcg (3333% DV)

📊 83.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.2mg

Biotin

300 mcg (100% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

200 mg (2000% DV)

📊 40.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 200mg

Calcium

500 mg (50% DV)

Iron

10 mg (55% DV)

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

250 mg (63% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 250mg

Zinc

20 mg (133% DV)

✅ 1.8× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 20mg UL 40mg

Selenium

200 mcg (286% DV)

📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.2mg UL 0.4mg

Copper

2 mg (103% DV)

✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 2mg UL 10mg

Manganese

1 mg (50% DV)

✅ Within RDA (0.4× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 1mg UL 11mg

Chromium

200 mcg (167% DV)

📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.2mg

Molybdenum

100 mcg (133% DV)

✅ 2.2× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.1mg UL 2mg

Potassium

99 mg (3% DV)

Betaine HCl

325 mg

📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews

This product: 325mg

Choline

200 mg

✅ Within RDA (0.4× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 200mg UL 3500mg

Inositol

188 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 188mg

Citrus Bioflavonoid Complex

100 mg

📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)

This product: 100mg

PABA

50 mg

📊 Market median: 500.0mg (9 products)

This product: 50mg

Quercetin

25 mg

📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)

This product: 25mg

Mixed Carotenoids

5.85 mg

Gamma-Tocopherol

67 mg

📊 4.5× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 67mg UL 1000mg

Other Ingredients

Microcrystalline Cellulose Cellulose Stearic Acid Silica Croscarmellose Sodium Magnesium Stearate coating

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: Take six tablets daily with meals or as directed by your healthcare practitioner.

1. Healthy 2-3 tablets 2. Average 3-4 tablets 3. Poor 4-6 tablets

⚠️ Warnings & Precautions

WARNING: Excess vitamin A intake may be toxic and may increase the risk of birth defects. Pregnant women and women who may become pregnant should not exceed 5,000 IU of preformed vitamin A (retinyl acetate) per day.

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

CAUTION: Keep out of the reach of children.

🧪 Formulation Notes

All Natural Vitamin E Blend

Additional Information

How many Multigenics should you take? The best way to assess the optimal intake of Multigenics is to discuss this matter with your healthcare provider. Otherwise, rate your diet to determine dosage. A healthy diet is low in saturated and trans fats and sugar, and high in fruits and vegetables.

Genetic Potential Through Nutrition

Optimum Multiple Vitamin/Mineral Formula

Fast-Release Tablet

LMJ02856

Lot# 0210062 03/12

PROD. MUO28

STORAGE: Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 7 55571 02367 8

DSLD Entry Date 2013-11-25

Product Type Other Combinations

Form Tablet or Pill

Brand Metagenics

DSLD ID 27558

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →