Vanilla

product on market Powder ON Optimum Nutrition Safety: 99/100
99/100

This product looks safe

  • Niacin: 50.6mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 52% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The primary ingredient profile consists of protein and carbohydrates, which are supported by strong evidence for muscle recovery and energy maintenance. These macronutrients are well-established in nutritional research for supporting general physiological function. The product maintains a high safety score, indicating a low risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50.6mg is 1.4× the Tolerable Upper Intake Level (35mg)

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Vanilla
Open Full PDF View on NIH DSLD →
Details

Label Data

334 Gram(s)
Serving Size
16
Servings
Other Combinations
Product Type
52%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
1630 Calorie(s)
Total Fat
19 Gram(s) (29% DV)
Cholesterol
140 mg (47% DV)
Total Carbohydrates
292 Gram(s) (97% DV)
Protein
74 Gram(s) (148% DV)
Vitamin A
6500 IU (130% DV)
Vitamin C
66 mg (110% DV)
500 IU (125% DV)
Within RDA (0.8× RDA) 608 studies (A:16, B:251)
30 IU (100% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
5.1 mg (340% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
5.2 mg (306% DV)
4.0× RDA — above typical dose 13 studies (A:0, B:1)
50.6 mg (253% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
5.3 mg (265% DV)
4.1× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
436 mcg (109% DV)
1.1× RDA — within safe limits 226 studies (A:10, B:105)
12.3 mcg (212% DV)
5.1× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
27 mg (270% DV)
5.4× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
1440 mg (144% DV)
Iron
5.3 mg (29% DV)
1160 mg (116% DV)
1.7× RDA — within safe limits 13 studies (A:0, B:3)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
239 mg (60% DV)
Within RDA (0.6× RDA) 316 studies (A:8, B:159)
120 mcg (100% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (100% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
18 mg (120% DV)
1.6× RDA — within safe limits 263 studies (A:6, B:134)
70 mcg (100% DV)
1.3× RDA — within safe limits 173 studies (A:0, B:67)
1 mg (50% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
Sodium
820 mg (34% DV)
Potassium
2200 mg (63% DV)
Market median: 5.0mg (298 products) 705 studies (A:5, B:123)
500 mg
Market median: 420.0mg (227 products)
Market median: 420.0mg (227 products)
250 mg
Within RDA (0.5× RDA) 38 studies (A:1, B:7)
250 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
5 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
Calories
1250 Calorie(s)
Total Fat
4 Gram(s) (6% DV)
Cholesterol
80 mg (27% DV)
Total Carbohydrates
253 Gram(s) (84% DV)
Sugar
20 Gram(s)
Protein
50 Gram(s) (100% DV)
Vitamin A
5000 IU (100% DV)
Vitamin C
60 mg (100% DV)
200 IU (50% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
30 IU (100% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
4.8 mg (320% DV)
4.0× RDA — above typical dose 76 studies (A:0, B:33)
4 mg (235% DV)
3.1× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
5 mg (200% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
10 mcg (167% DV)
4.2× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (100% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
25 mg (250% DV)
5.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
630 mg (63% DV)
Iron
5 mg (28% DV)
460 mg (46% DV)
Within RDA (0.7× RDA) 13 studies (A:0, B:3)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
140 mg (35% DV)
Within RDA (0.3× RDA) 316 studies (A:8, B:159)
15 mg (100% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
70 mcg (100% DV)
1.3× RDA — within safe limits 173 studies (A:0, B:67)
1 mg (50% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
120 mcg (100% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
75 mcg (100% DV)
1.7× RDA — within safe limits 3 studies — no high-quality reviews
Sodium
430 mg (18% DV)
Potassium
975 mg (28% DV)
Market median: 5.0mg (298 products) 705 studies (A:5, B:123)
500 mg
Market median: 420.0mg (227 products)
Market median: 420.0mg (227 products)
250 mg
Within RDA (0.5× RDA) 38 studies (A:1, B:7)
250 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
5 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews

Other Ingredients

Maltodextrin Whey Protein concentrate Calcium Caseinate Egg Albumen sweet Dairy Whey Artificial Flavors Dipotassium Phosphate Magnesium Aspartate Dicalcium Phosphate Calcium Citrate Ascorbic Acid Niacinamide Zinc Citrate Beta Carotene D-Calcium Pantothenate D-Alpha Tocopheryl Succinate Selenomethionine Copper Gluconate Ferrous Fumarate Manganese Amino Acid Chelate Thiamin Mononitrate Pyridoxine Hydrochloride Riboflavin Chromium Picolinate Folic Acid Biotin Molybdenum Amino Acid Chelate Cholecalciferol Potassium Iodide Cyanocobalamin Medium Chain Triglyceride Lecithin Acesulfame Potassium
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Add two heaping scoops of Serious Mass to a blender filled with 24 oz. of water. Blend for 45-60 seconds. Then add a few ice cubes and, if desired, other calorie-contributing ingredients (see "Supercharge Your Serious Mass" below) and blend for an additional 30-45 seconds. Tips: Mixing two scoops of Serious Mass with 24 fl. oz. of nonfat or low fat milk instead of water will give you a thicker, creamier, higher-calorie shake. New users may find it beneficial to begin with 1/2 of a serving daily for the first week and then gradually increase to 1 or more full servings several times a day. Serious Mass is a substantial weight-gain supplement that can be used to feed serious calorie needs in a variety of different ways. Between Meals: Drink 1/2 - 1 serving of Serious Mass between meals to maintain positive nitrogen balance and support a high-calorie diet. Post-Workout: Begin drinking 1/2 - 1 serving of Serious Mass 30-45 minutes following exercise to support maximum recovery. Before Bed: Drink 1/2 - 1 serving of Serious Mass about 45-60 minutes before bed to provide nutrients to recovering muscle throughout the night. Note: For best results use Serious Mass combined with intense weight training (3-5 times per week) and a sensible whole foods diet. Also, keep in mind that sufficient recovery between workouts impacts your ability to gain lean mass. Allowing at least 48 hours between workout involving the same body parts is recommended.

Supercharge your Serious Mass by adding one or more of these foods to your shake. Serving size Calories 1/2 cup granola 250 1/4 cup chocolate chip 198 1 tbsp. peanut butter 190 1 oz. almonds 167 1 oz. peanuts 164 1/2 cup ice cream 160 1 cup whole milk 150 1/2 cup coconut 139 1 tbsp. flaxseed oil 115 1/2 cup oat bran 108 1 small banana 105 1 tbsp. honey 64 1 tbsp. molasses 43

Warnings & Precautions

Caution: Keep out of reach of children.

Do not take this product if you are pregnant or nursing a baby. Check with a qualified healthcare professional before using this product if you are under 18 years of age or if you have any known or suspected medical condition(s) including diabetes or hypoglycemia, and/or if you are taking any prescription or OTC medication(s).

Check with a qualified healthcare professional before using this product if you are under 18 years of age or if you have any known or suspected medical condition(s) including diabetes or hypoglycemia, and/or if you are taking any prescription or OTC medication(s).

Allergen Information: Contains milk, egg, wheat, (glutamine peptides) and soy (lecithin) ingredients.

Formulation Notes

1250 calories 50 g protein 250 g+ carbs 25 vitamins & minerals

No sugar added

We've consolidated over 1,250 calories, 50 grams of protein, 250-plus grams of carbohydrates, and 25 vitamins & minerals with added glutamine and creatine into every serving. It's time to stop thinking small; get serious - Serious Mass. Beyond the basics 1,250 calories per serving in water; 1,630-plus calories when made with low fat milk. 50 grams of protein from a combination of faster and slower digesting sources including whey, casein, and egg. 250-plus grams of carbohydrates to support fueling of intense workouts and aid in the replenishment of glycogen stores - with no added sugar. Enhanced with creatine, l-glutamine & glutamine peptides, choline, inositol, PABA, and MCTs. 25 vitamins & essential minerals with an emphasis on B-vitamins and antioxidants.

Additional Information

Store in a cool, dry place.

Contents sold by weight, not volume. Some settling may occur.

Serving scoop included, but may settle to the bottom during shipping Not a sugar-free product. See back panel for complete nutritional information.

Metadata

Product Details

DSLD Entry Date2022-06-16
Product TypeOther Combinations
FormPowder
DSLD ID268888
Data Updated2026-04-11
Research

Research Evidence

739
Research Sources
47
Avg Quality
472
Clinical Trial
139
Meta Analysis
74
Systematic Review
47
Rct
2
Regulatory Source
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data
Meta Analysis JAMA psychiatry 2021 PubMed DOI
A HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024 PubMed DOI
B Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis
Systematic Review BMC medicine 2019 PubMed DOI
B Efficacy of Creatine Supplementation Combined with Resistance Training on Muscle Strength and Muscle Mass in Older Females: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2021 PubMed DOI
B The Effects of Creatine Supplementation on Upper- and Lower-Body Strength and Power: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2025 PubMed DOI
B Meta-analysis of the efficacy and safety of Finerenone in diabetic kidney disease
Meta Analysis Medicine 2026 PubMed DOI
B Creatine and creatine analogues in hypertension and cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
B HMG CoA reductase inhibitors (statins) for dialysis patients
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.