The Big One+
99/100
This product looks safe
- Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
- 70% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
Label Data
1 Capsule(s)
Serving Size
Multi-Vitamin and Mineral (MVM)
Product Type
70%
Evidence Coverage
Supplement Facts — Evidence Check
Vitamin A
8000 IU
(160% DV)
Vitamin C
150 mg
(250% DV)
2000 IU
(500% DV)
📊 3.3× RDA — above typical dose (UL: 0.1 mg)
📚 604 studies (Tier A: 16, B: 251)
100 IU
(333% DV)
📊 4.5× RDA — above typical dose (UL: 1000 mg)
📚 177 studies (Tier A: 3, B: 90)
100 mcg
(125% DV)
✅ Within RDA (0.8× RDA of 0.12 mg)
📚 273 studies (Tier A: 9, B: 175)
25 mg
(1667% DV)
📊 20.8× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
25 mg
(1471% DV)
📊 19.2× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
100 mg
(500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
25 mg
(1250% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
400 mcg
(100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg)
📚 225 studies (Tier A: 10, B: 105)
100 mcg
(1667% DV)
📊 41.7× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
200 mcg
(67% DV)
📊 6.7× RDA — above typical dose
📚 26 studies (Tier A: 0, B: 11)
100 mg
(1000% DV)
📊 20.0× RDA — above typical dose
📚 1 studies — no high-quality reviews
100 mcg
(67% DV)
✅ Within RDA (0.7× RDA of 0.15 mg)
📚 243 studies (Tier A: 4, B: 133)
15 mg
(100% DV)
✅ 1.4× RDA — within safe limits
📚 258 studies (Tier A: 6, B: 134)
100 mcg
(143% DV)
✅ 1.8× RDA — within safe limits
📚 172 studies (Tier A: 0, B: 67)
1 mg
(50% DV)
✅ 1.1× RDA — within safe limits
📚 36 studies (Tier A: 0, B: 11)
5 mg
(250% DV)
✅ 2.2× RDA — within safe limits
📚 8 studies — no high-quality reviews
100 mcg
(83% DV)
✅ 2.9× RDA — within safe limits
📚 197 studies (Tier A: 1, B: 55)
50 mcg
(67% DV)
✅ 1.1× RDA — within safe limits
📚 2 studies — no high-quality reviews
25 mg
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
1 mg
📊 Market median: 3.0mg (58 products)
📚 2 studies — no high-quality reviews
50 mcg
📊 Market median: 0.5mg (6 products)
📚 1 studies (Tier A: 0, B: 1)
Other Ingredients
vegetarian capsule
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (76% of products)
Nutrient (58% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
DIRECTIONS: One (1) capsule daily with a meal as a dietary supplement, or as directed by a healthcare professional.
⚠️ Warnings & Precautions
Keep tightly closed in a cool, dry place, out of the reach of children.
Physician monitoring of Vitamin D level recommended.
🧪 Formulation Notes
Gluten and Excipient Free.
2000 IU Vitamin D without Iron
The Big One(TM)+ contains 2000 IU of Vitamin D-3 for added immune and bone support, a more bioavailable form of beta carotene, and methylated forms of B-12 and Folate.
2000 IU Vitamin D without Iron
Additional Information
Keep tightly closed in a cool, dry place, out of the reach of children.
Manufactured in a GMP Certified Facility
523008A EXP 2/14
ESSENTIALS
Vitamin E is derived from soy oil.
V-07
Product Details
UPC / SKU
8 38287 00523 0
DSLD Entry Date
2013-08-23
Product Type
Multi-Vitamin and Mineral (MVM)
Form
Capsule
Brand
Metabolic Maintenance
DSLD ID
25125
Data Updated
2026-04-11
Research Evidence
337
Research Sources
54
Avg Quality Score
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A
Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
A
Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
A
Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
A
Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
A
Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
A
Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
A
Food fortification with multiple micronutrients: impact on health outcomes in general population
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