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Fem Essentials

product on market Tablet or Pill Metagenics Safety: 98/100
98/100

This product looks safe

  • Niacin: 420mg is 12.0× the Tolerable Upper Intake Level (35mg)
  • Folate: 1360mg is 1360.0× the Tolerable Upper Intake Level (1.0mg)
  • 61% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains vitamins A, C, D, and E, which are supported by strong evidence for maintaining immune function and antioxidant defense. These nutrients play essential roles in cellular protection and overall health. The evidence coverage for this specific profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 420mg is 12.0× the Tolerable Upper Intake Level (35mg)

Folate: 1360mg is 1360.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Fem Essentials
Open Full PDF View on NIH DSLD →
Details

Label Data

6 Tablet(s)
Serving Size
15
Servings
Other Combinations
Product Type
61%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
2 Gram(s) (1% DV)
Vitamin A
3000 mcg (333% DV)
Vitamin C
1200 mg (1333% DV)
0.5 mcg (3% DV)
Market median: 0.03mg (3448 products) 608 studies (A:16, B:251)
67 mg (447% DV)
4.5× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
30 mg (2500% DV)
25.0× RDA — above typical dose 76 studies (A:0, B:33)
34 mg (2615% DV)
26.2× RDA — above typical dose 13 studies (A:0, B:1)
420 mg (2625% DV)
Exceeds UL by 12.0× (UL: 35 mg) 196 studies (A:5, B:63)
40 mg (2353% DV)
30.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1360 mcg DFE (340% DV)
Exceeds UL by 1360.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
200 mcg (8333% DV)
83.3× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
200 mg (4000% DV)
40.0× RDA — above typical dose 2 studies — no high-quality reviews
200 mg (36% DV)
Within RDA (0.4× RDA) 38 studies (A:1, B:7)
Calcium
500 mg (38% DV)
Iron
10 mg (56% DV)
150 mcg (100% DV)
Within RDA (1.0× RDA) 245 studies (A:4, B:133)
250 mg (60% DV)
Within RDA (0.6× RDA) 316 studies (A:8, B:159)
20 mg (182% DV)
1.8× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (364% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
2 mg (222% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
1 mg (43% DV)
Within RDA (0.4× RDA) 9 studies — no high-quality reviews
200 mcg (571% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)
100 mcg (222% DV)
2.2× RDA — within safe limits 3 studies — no high-quality reviews
Potassium
99 mg (2% DV)
325 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
188 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
25 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Mixed Carotenoids
5.85 mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Silica Coating
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 6 tablets daily with meals or as directed by your healthcare practitioner.

Warnings & Precautions

Caution: If pregnant or nursing consult your healthcare practitioner before use. Warning: Excess vitamin A intake may be toxic and may increase the risk of birth defects. Pregnant women and women who may become pregnant should not exceed 10,000 IU of preformed vitamin A (retinyl acetate) per day.

Tamper Evident: Do not use if safety seal is missing or broken.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Formulation Notes

Fem Essentials is a comprehensive multiple vitamin/mineral formula featuring: High levels of ratio-balanced B vitamins to support healthy adrenal and liver function, homocysteine metabolism, and a host of other metabolic processes. Antioxidant nutrients vitamins A, C, E, as well as Caro-Xan - our proprietary blend of beta-carotene and Betatene mixed carotenoids. High levels of folic acid (calcium L-5-MTHF) to support health for women who may become pregnant.

This product is non-GMO and gluten-free.

GF Certified gluten-free

Comprehensive nutritional support for women

Caro-xan, a proprietary blend of beta-carotene and Betatena mixed carotenoids.

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Practitioner exclusive

Metadata

Product Details

UPC / SKU7 55571 01602 7
DSLD Entry Date2020-03-24
Product TypeOther Combinations
FormTablet or Pill
DSLD ID216425
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.