Fem Essentials

product on market Tablet or Pill Metagenics 🟢 Safety: 98/100
Brand: Metagenics
🟢 98/100

This product looks safe

  • Niacin: 420mg is 12.0× the Tolerable Upper Intake Level (35mg)
  • Folate: 1360mg is 1360.0× the Tolerable Upper Intake Level (1.0mg)
  • 61% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 420mg is 12.0× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 1360mg is 1360.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

6 Tablet(s) Serving Size
15 Servings
Other Combinations Product Type
61% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
2 Gram(s) (1% DV)
Vitamin A
3000 mcg (333% DV)
Vitamin C
1200 mg (1333% DV)
0.5 mcg (3% DV)
📊 Market median: 0.03mg (3448 products) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0005mg UL 0.1mg
67 mg (447% DV)
📊 4.5× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 67mg UL 1000mg
30 mg (2500% DV)
📊 25.0× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 30mg
34 mg (2615% DV)
📊 26.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 34mg
420 mg (2625% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 12.0× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 420mg UL 35mg
40 mg (2353% DV)
📊 30.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 40mg UL 100mg
1360 mcg DFE (340% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1360.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 1360mg UL 1.0mg
200 mcg (8333% DV)
📊 83.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.2mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
200 mg (4000% DV)
📊 40.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 200mg
200 mg (36% DV)
✅ Within RDA (0.4× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 200mg UL 3500mg
Calcium
500 mg (38% DV)
Iron
10 mg (56% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
250 mg (60% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 250mg
20 mg (182% DV)
✅ 1.8× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 20mg UL 40mg
200 mcg (364% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (222% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
1 mg (43% DV)
✅ Within RDA (0.4× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 1mg UL 11mg
200 mcg (571% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg
100 mcg (222% DV)
✅ 2.2× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.1mg UL 2mg
Potassium
99 mg (2% DV)
325 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 325mg
188 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 188mg
100 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 100mg
50 mg
📊 Market median: 500.0mg (9 products)
This product: 50mg
25 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 25mg
Mixed Carotenoids
5.85 mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Silica Coating

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult Female (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take 6 tablets daily with meals or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Caution: If pregnant or nursing consult your healthcare practitioner before use. Warning: Excess vitamin A intake may be toxic and may increase the risk of birth defects. Pregnant women and women who may become pregnant should not exceed 10,000 IU of preformed vitamin A (retinyl acetate) per day.

Tamper Evident: Do not use if safety seal is missing or broken.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

🧪 Formulation Notes

Fem Essentials is a comprehensive multiple vitamin/mineral formula featuring: High levels of ratio-balanced B vitamins to support healthy adrenal and liver function, homocysteine metabolism, and a host of other metabolic processes. Antioxidant nutrients vitamins A, C, E, as well as Caro-Xan - our proprietary blend of beta-carotene and Betatene mixed carotenoids. High levels of folic acid (calcium L-5-MTHF) to support health for women who may become pregnant.

This product is non-GMO and gluten-free.

GF Certified gluten-free

Comprehensive nutritional support for women

Caro-xan, a proprietary blend of beta-carotene and Betatena mixed carotenoids.

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Practitioner exclusive

Product Details

UPC / SKU 7 55571 01602 7
DSLD Entry Date 2020-03-24
Product Type Other Combinations
Form Tablet or Pill
Brand Metagenics
DSLD ID 216425
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
PubMed DOI Cochrane
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
PubMed DOI Cochrane
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
PubMed DOI Cochrane
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
PubMed DOI Cochrane
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI
View all evidence for Vitamin A →

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