🟢 98/100

This product looks safe

  • Niacin: 420mg is 12.0× the Tolerable Upper Intake Level (35mg)
  • Folate: 1360mg is 1360.0× the Tolerable Upper Intake Level (1.0mg)
  • 63% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 420mg is 12.0× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 1360mg is 1360.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

6 Tablet(s) Serving Size
15 Servings
Other Combinations Product Type
63% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
2 Gram(s) (1% DV)
Vitamin A
3000 mcg (333% DV)
Vitamin C
1200 mg (1333% DV)
0.5 mcg (3% DV)
📊 Market median: 0.03mg (3448 products) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0005mg UL 0.1mg
67 mg (447% DV)
📊 4.5× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 67mg UL 1000mg
30 mg (2500% DV)
📊 25.0× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 30mg
34 mg (2615% DV)
📊 26.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 34mg
420 mg (2625% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 12.0× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 420mg UL 35mg
40 mg (2353% DV)
📊 30.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 40mg UL 100mg
1360 mcg DFE (340% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1360.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 1360mg UL 1.0mg
200 mcg (8333% DV)
📊 83.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.2mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
200 mg (4000% DV)
📊 40.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 200mg
200 mg (36% DV)
✅ Within RDA (0.4× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 200mg UL 3500mg
Calcium
500 mg (38% DV)
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
250 mg (60% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 250mg
20 mg (182% DV)
✅ 1.8× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 20mg UL 40mg
200 mcg (364% DV)
📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.2mg UL 0.4mg
2 mg (222% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
1 mg (43% DV)
✅ Within RDA (0.4× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 1mg UL 11mg
200 mcg (571% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg
100 mcg (222% DV)
✅ 2.2× RDA — within safe limits 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.1mg UL 2mg
Potassium
99 mg (2% DV)
325 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 325mg
188 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 188mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 100mg
📊 Market median: 500.0mg (9 products)
This product: 50mg
25 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 25mg
Mixed Carotenoids
5.85 mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Silica Coating

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (71% of products) Nutrient (61% of products) Approved Health (1% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take six tablets daily with meals or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Excess vitamin A may contribute to a risk of birth defects. Pregnant women and women who may become pregnant should not exceed 3,000 mcg of preformed vitamin A (retinyl acetate) per day unless instructed to do so by a healthcare practitioner.

Caution: Keep out of the reach of children.

🧪 Formulation Notes

Multigenics without Iron is a unique vitamin and mineral formula designed for optimal tablet disintegration and digestibility, featuring: High levels of ratio-balanced B vitamins with B12 to support homocysteine metabolism. Caro-xan, our proprietary blend of beta-carotene and Betatene mixed carotenoids. A 2-to-1 ratio of calcium to magnesium for bone support.

This product is non-GMO and gluten-free.

Optimum multiple vitamin/mineral formula

Additional Information

Storage: Keep tightly closed in a cool, dry place.

GF Certified Gluten-Free

Practitioner Exclusive

Fast-release tablet

Product Details

UPC / SKU 7 55571 02410 7
DSLD Entry Date 2020-03-24
Product Type Other Combinations
Form Tablet or Pill
Brand Metagenics
DSLD ID 216376
Data Updated 2026-04-11

Research Evidence

566 Research Sources
56 Avg Quality Score
240 Meta Analysis
100 Clinical Trial
74 Systematic Review
71 Guideline
58 Rct
11 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
1 Observational
1 Openfda Safety
A Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency
Meta Analysis Nature medicine 2025
A Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Meta Analysis The Cochrane database of systematic reviews 2014
A Serum or plasma ferritin concentration as an index of iron deficiency and overload
Meta Analysis The Cochrane database of systematic reviews 2021
A Non-invasive diagnostic tests for Helicobacter pylori infection
Meta Analysis The Cochrane database of systematic reviews 2018
A Hypoxia-inducible factor stabilisers for the anaemia of chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2022
A Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations
Meta Analysis The Cochrane database of systematic reviews 2021
A Fortification of condiments and seasonings with iron for preventing anaemia and improving health
Meta Analysis The Cochrane database of systematic reviews 2023
A Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2024
A Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review
Meta Analysis Neuroscience and biobehavioral reviews 2025
View all evidence for Iron →

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