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One Daily Active

product on market Tablet or Pill 21st Century Safety: 99/100
99/100

This product looks safe

  • Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • 64% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This product contains a blend of fat-soluble and water-soluble vitamins that support immune function and bone health. There is strong research evidence supporting the roles of vitamins A, C, D, E, and K in maintaining general physiological processes. The ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for One Daily Active
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Botanical with Nutrients
Product Type
64%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
5000 IU (100% DV)
Vitamin C
120 mg (200% DV)
400 IU (100% DV)
Within RDA (0.7× RDA) 608 studies (A:16, B:251)
60 IU (200% DV)
2.7× RDA — within safe limits 179 studies (A:3, B:90)
25 mcg (31% DV)
Within RDA (0.2× RDA) 275 studies (A:9, B:175)
4.5 mg (300% DV)
3.8× RDA — above typical dose 76 studies (A:0, B:33)
5.1 mg (300% DV)
3.9× RDA — above typical dose 13 studies (A:0, B:1)
40 mg (200% DV)
Exceeds UL by 1.1× (UL: 35 mg) 196 studies (A:5, B:63)
6 mg (300% DV)
4.6× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
18 mcg (300% DV)
7.5× RDA — above typical dose 139 studies (A:1, B:44)
40 mcg (13% DV)
1.3× RDA — within safe limits 27 studies (A:0, B:11)
10 mg (100% DV)
2.0× RDA — within safe limits 2 studies — no high-quality reviews
Calcium
110 mg (11% DV)
Iron
9 mg (50% DV)
48 mg (4% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
40 mg (10% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
15 mg (100% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
45 mcg (64% DV)
Within RDA (0.8× RDA) 173 studies (A:0, B:67)
2 mg (100% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
100 mcg (83% DV)
2.9× RDA — within safe limits 199 studies (A:1, B:55)
25 mcg (33% DV)
Within RDA (0.6× RDA) 3 studies — no high-quality reviews
180 mg (5% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Potassium
200 mg (5% DV)
Nickel
5 mcg
Tin
10 mcg
6 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
10 mcg
Market median: 0.5mg (6 products) 1 studies (A:0, B:1)
150 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Market median: 450.0mg (390 products) 160 studies (A:0, B:63)

Other Ingredients

Cellulose Starch Croscarmellose Sodium Stearic Acid Silicon Dioxide Magnesium Stearate Titanium Dioxide Artificial Colors
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: As a dietary supplement, adults take one (1) tablet daily with any meal, or as directed by a health care provider. Do not exceed recommended dosage.

Warnings & Precautions

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Formulation Notes

No Added Sugar, Salt, Yeast, Preservatives, Artificial Flavors.

Additional Information

Store at room temperature.

Unconditionally guaranteed for purity, freshness and label potency.

MADE IN USA

1205

Metadata

Product Details

UPC / SKU7 40985 22656 8
DSLD Entry Date2012-07-25
Product TypeBotanical with Nutrients
FormTablet or Pill
Brand21st Century
DSLD ID11548
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.