Perfect Calm Multivitamin by New Chapter — Ingredients, Evidence & Safety

🟢 99/100

This product looks safe

Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)
70% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)

Label Data

3 Tablet(s) Serving Size

24 Servings

Botanical with Nutrients Product Type

70% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

5000 IU (100% DV)

Vitamin C

75 mg (125% DV)

Vitamin D3

1000 IU (250% DV)

✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.025mg UL 0.1mg

Vitamin E

30 IU (100% DV)

✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 20.1mg UL 1000mg

Vitamin K

80 mcg (100% DV)

✅ Within RDA (0.7× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.08mg

Thiamin

15 mg (1000% DV)

📊 12.5× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 15mg

Riboflavin

10 mg (588% DV)

📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 10mg

Niacin

45 mg (225% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 45mg UL 35mg

Vitamin B6

20 mg (1000% DV)

📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 20mg UL 100mg

Folate

400 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.4mg UL 1.0mg

Vitamin B12

60 mcg (1000% DV)

📊 25.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.06mg

Biotin

300 mcg (100% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

45 mg (450% DV)

📊 9.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 45mg

Iodine

90 mcg (60% DV)

✅ Within RDA (0.6× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.09mg UL 1.1mg

Zinc

7.5 mg (50% DV)

✅ Within RDA (0.7× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 7.5mg UL 40mg

Selenium

100 mcg (143% DV)

✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.1mg UL 0.4mg

Copper

750 mcg (37% DV)

✅ Within RDA (0.8× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.75mg UL 10mg

Manganese

2 mg (100% DV)

✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 2mg UL 11mg

Chromium

100 mcg (83% DV)

✅ 2.9× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.1mg

Molybdenum

10 mcg (13% DV)

✅ Within RDA (0.2× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.01mg UL 2mg

Comprehensive Stress Support Blend

242 mg

Immune Support Blend

56.2 mg

Digestive Support Blend

56.2 mg

organic Turmeric (rhizome) powder

13.6 mg

📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)

This product: 13.6mg

Ginger (rhizome) hydroethanolic extract

8 mg

📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)

This product: 8mg

organic Turmeric (rhizome) supercritical extract

4 mg

📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)

This product: 4mg

organic Ginger (rhizome) supercritical extract

2 mg

📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)

This product: 2mg

Other Ingredients

Culture Media organic Gum Acacia Maltodextrin Olive Oil Silicon Dioxide Lithothamnion Lac Resin Carnauba wax Magnesium Oxide Magnesium Carbonate

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Kosher Organic Gluten Free

Product Information

📋 Directions for Use

Suggested Use: Three tablets daily. Can be taken anytime, even on an empty stomach.

Can be taken on an empty stomach

⚠️ Warnings & Precautions

Not recommended for use in children.

Caution: As with any dietary or herbal supplement, you should advise your healthcare practitioner of the use of this product.

If you are taking medication, or are nursing, pregnant, or considering pregnancy, you should consult your healthcare professional prior to using this product.

Discontinue use and contact your healthcare professional if you experience a side effect or an allergic reaction.

Do not exceed suggested use.

Keep out of reach of children.

Contains: Fermented soy and fermented wheat (as food source for Saccharomyces cerevisiae).

🧪 Formulation Notes

Non-GMO project verified.

Gluten free; 100% Vegetarian; No artificial flavors or colors.

Made with organic vegetables & herbs

Contains: Fermented soy and fermented wheat (as food source for Saccharomyces cerevisiae).

Certified Organic by International Certification Services, Inc., Medina, ND, USA

Additional Information

Probiotic-cultured.

Whole-food complexed.

Get the whole truth! Sign up for our e-newsletter at: newchapter.com/newsletter Please refer to newchapter.com for more information about this product and its benefits.

Please recycle this bottle after use.

0337-E01

ICS Certified Organic

With nutrients that soothe

Whole-food cultured multivitamin with nutrients for soothing stress support

The wheat has been processed to allow this food to meet the Food and Drug Administration (FDA) requirements for gluten-free foods.

Product Details

DSLD Entry Date 2018-01-25

Product Type Botanical with Nutrients

Form Tablet or Pill

Brand New Chapter

DSLD ID 82562

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →