🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 80% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
80% Evidence Coverage

Supplement Facts — Evidence Check

69 mg
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 69mg UL 3500mg
1 mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 1mg
Vitamins
✅ Within RDA (0.6× RDA of 90 mg) 📚 245 studies (Tier A: 6, B: 97)
RDA 90mg This product: 50mg UL 2000mg
📊 3.3× RDA — above typical dose (UL: 3.0 mg) 📚 240 studies (Tier A: 5, B: 97)
RDA 0.9mg This product: 3mg UL 3.0mg
15 mcg
✅ Within RDA (0.1× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)
RDA 0.12mg This product: 0.015mg
12.5 mcg
✅ Within RDA (0.8× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0125mg UL 0.1mg
📊 10.4× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 12.5mg
📊 9.6× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 12.5mg
15 mg
✅ 1.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 15mg UL 35mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 12.5mg
📊 9.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 12.5mg UL 100mg
📊 9.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 12.5mg UL 100mg
200 mcg
✅ Within RDA (0.5× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.2mg UL 1.0mg
✅ Within RDA (0.1× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.05mg UL 1.0mg
250 mcg
📊 104.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.25mg
35 mcg
✅ 1.2× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.035mg
Minerals
Iron
12 mg
10 mg
✅ Within RDA (0.9× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 10mg UL 40mg
1.3 mg
✅ Within RDA (0.6× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 1.3mg UL 11mg
149.5 mcg
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.1495mg UL 1.1mg
25 mcg
✅ Within RDA (0.7× RDA of 0.035 mg) 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.025mg
25 mcg
✅ Within RDA (0.6× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.025mg UL 2mg
25 mcg
✅ Within RDA (0.5× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.025mg UL 0.4mg

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Vegan Vegetarian Pregnant Women Adult Female (18 - 50 Years) Lactating Dairy Free

Product Information

📋 Directions for Use

Directions for use: Adults: Take 1 tablet twice daily with food for at least one month before conception, during pregnancy and lactation, or as directed by your healthcare professional.

⚠️ Warnings & Precautions

This product contains selenium which is toxic in high doses. A daily dose of 150 micrograms for adults of selenium from dietary supplements should not be exceeded. When trying to conceive and during the first trimester of pregnancy, folic acid helps to prevent neural tube defects (NTD) such as spina bifida and/or anencephaly. Warning - Do not exceed the stated dose except on medical advice. If you have had a baby with neural tube defect/spina bifida, seek medical advice.

When trying to conceive and during the first trimester of pregnancy, folic acid helps to prevent neural tube defects (NTD) such as spina bifida and/or anencephaly. If you have had a baby with neural tube defect/spina bifida, seek medical advice.

If you have had a baby with neural tube defect/spina bifida, seek medical advice.

Stop taking this medication if you experience tingling, burning or numbness and see your healthcare practitioner as soon as possible. [Contains vitamin B6]. Do not use if cap and/or bottle seals are missing or broken.

Practitioner only

If symptoms persist consult your healthcare professional.

Advise your doctor of any medicine you take during pregnancy, particularly in your first trimester.

Vitamin and mineral supplements should not replace a balanced diet.

🧪 Formulation Notes

Pregnancy Care Advanced is scientifically formulated to provide key nutritional support during preconception, pregnancy and lactation; including high strength iodine, vitamin K2, absorption friendly minerals, activated B vitamins, lutein and choline.

Specialised nutrition for preconception, pregnancy and lactation.

Additional Information

Store below 30 degrees Celsius.

AUST L 351517

Product Details

UPC / SKU 9 315771 011782
DSLD Entry Date 2024-01-24
Product Type Other Combinations
Form Tablet or Pill
Brand Metagenics
DSLD ID 305428
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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