Centrum Silver Men 50+ by GSK — Ingredients, Evidence & Safety

🟢 98/100

This product looks safe

Vitamin D3: 25mg is 250.0× the Tolerable Upper Intake Level (0.1mg)
Folate: 500mg is 500.0× the Tolerable Upper Intake Level (1.0mg)
74% of ingredients have research evidence

D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vitamin D3: 25mg is 250.0× the Tolerable Upper Intake Level (0.1mg)

⚠️ Folate: 500mg is 500.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

200 Servings

Other Combinations Product Type

74% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

1050 mg (117% DV)

Vitamin C

120 mg (133% DV)

Vitamin D3

25 mg (125% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 250.0× (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 25mg UL 0.1mg

Vitamin E

27 mg (180% DV)

✅ 1.8× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 27mg UL 1000mg

Vitamin K

60 mcg (50% DV)

✅ Within RDA (0.5× RDA of 0.12 mg) 📚 273 studies (Tier A: 9, B: 175)

RDA 0.12mg This product: 0.06mg

Thiamine

1.5 mg (125% DV)

✅ 1.2× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 1.5mg

Riboflavin

1.7 mg (131% DV)

✅ 1.3× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 1.7mg

Niacin

20 mg (125% DV)

✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 20mg UL 35mg

Vitamin B6

6 mg (353% DV)

📊 4.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 6mg UL 100mg

Folate

500 mcg DFE (125% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 500.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 500mg UL 1.0mg

Vitamin B12

100 mcg (4167% DV)

📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.1mg

Biotin

30 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.03mg

Pantothenic Acid

10 mg (200% DV)

✅ 2.0× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 10mg

Calcium

210 mg (16% DV)

Phosphorus

20 mg (2% DV)

📊 Market median: 99.0mg (503 products) 📚 12 studies (Tier A: 0, B: 3)

RDA 700mg This product: 20mg UL 4000mg

Iodine

150 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.15mg UL 1.1mg

Magnesium

75 mg (18% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 75mg

Zinc

15 mg (136% DV)

✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 15mg UL 40mg

Selenium

21 mcg (38% DV)

✅ Within RDA (0.4× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.021mg UL 0.4mg

Copper

0.5 NP (56% DV)

✅ Within RDA (0.6× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.5mg UL 10mg

Manganese

4 mg (174% DV)

✅ 1.7× RDA — within safe limits 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 4mg UL 11mg

Chromium

60 mcg (171% DV)

✅ 1.7× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.06mg

Molybdenum

50 mcg (111% DV)

✅ 1.1× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 0.045mg This product: 0.05mg UL 2mg

Chloride

72 mg (3% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 72mg

Potassium

80 mg (2% DV)

Lutein

300 mcg

📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)

This product: 0.3mg

Lycopene

600 mcg

📊 Market median: 10.0mg (35 products) 📚 5 studies (Tier A: 0, B: 2)

This product: 0.6mg

Other Ingredients

Calcium Carbonate Potassium Chloride Magnesium Oxide Ascorbic Acid Microcrystalline Cellulose Dibasic Calcium Phosphate DL-Alpha-Tocopheryl Acetate Maltodextrin Crospovidone Beta-Carotene Biotin Blue 2 Lake Calcium Pantothenate Cholecalciferol Chromium Picolinate Copper Sulfate Cyanocobalamin Folic Acid Hypromellose Lutein Lycopene Magnesium Stearate Magnesium Sulfate Medium Chain Triglyceride Niacinamide Phytonadione Polydextrose Potassium Iodide Pyridoxine Hydrochloride Red 40 Lake Riboflavin Silicon Dioxide Sodium Molybdate Sodium Selenate Talc Thiamine Thiamine Mononitrate Titanium Dioxide Vitamin A Acetate Yellow 6 Lake Zinc Oxide

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult Male (18-50 Years) Seniors/Mature (>50 Years) - Men ONLY Gluten Free

Product Information

📋 Directions for Use

Suggested use: Adults - Take one (1) tablet daily with food.

⚠️ Warnings & Precautions

Not formulated for use in children.

Do not exceed suggested use.

As with any supplement, if you are taking medication, consult your doctor before use.

If taking other supplements, read label, since supplements may contain the same ingredient.

Keep out of reach of children.

Bottle sealed with printed foil under cap. Do not use if foil is torn.

Not a replacement for cholesterol-lowering drugs. This product is not intended to provide daily intake of lutein. Take with a diet rich in fruits and vegetables.

🧪 Formulation Notes

Supports heart, brain, eye health + muscle function B-Vitamins and lycopene help promote heart health. Not a replacement for cholesterol-lowering drugs. Zinc and B-Vitamins help support normal brain function. Vitamins A, C and E, and Lutein support healthy eyes. This product is not intended to provide daily intake of lutein. Take with a diet rich in fruits and vegetables. Magnesium, Vitamins D and B6 help support muscle function.

Made in Canada.

Verified Non-GMO & gluten free! Non-GMO applies to Centrum & Centrum Silver Tablets only, learn more at centrum.com.

Additional Information

Store at room temperature. Keep bottle tightly closed.

Questions? Comments? Call 1-877-236-8786 For most recent product information, visit www.centrum.com

Product Details

UPC / SKU 3 05734 75870 9

DSLD Entry Date 2024-01-24

Product Type Other Combinations

Form Tablet or Pill

Brand GSK

DSLD ID 304930

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →