🟢 99/100

This product looks safe

  • Vanadium: 375mg is 208.3× the Tolerable Upper Intake Level (1.8mg)
  • 65% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vanadium: 375mg is 208.3× the Tolerable Upper Intake Level (1.8mg)

Label Data

2 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
65% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
1120 mcg (124% DV)
Vitamin C
125 mg (139% DV)
2.5 mcg (13% DV)
✅ Within RDA (0.2× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.0025mg UL 0.1mg
67 mg (447% DV)
📊 4.5× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 67mg UL 1000mg
10 mg (833% DV)
📊 8.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 10mg
10 mg (769% DV)
📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 10mg
32 mg (200% DV)
✅ 2.3× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 32mg UL 35mg
10 mg (588% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
Quatrefolic
340 mcg DFE (85% DV)
250 mcg (10417% DV)
📊 104.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.25mg
500 mcg (1667% DV)
📊 16.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.5mg
100 mg (2000% DV)
📊 20.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 100mg
18 mg (3% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 18mg UL 3500mg
Calcium
50 mg (4% DV)
50 mcg (33% DV)
✅ Within RDA (0.3× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.05mg UL 1.1mg
50 mg (12% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 50mg
6.5 mg (59% DV)
✅ Within RDA (0.6× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 6.5mg UL 40mg
50 mcg (91% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
0.5 mg (56% DV)
✅ Within RDA (0.6× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.5mg UL 10mg
0.25 mg (11% DV)
✅ Within RDA (0.1× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 0.25mg UL 11mg
250 mcg (714% DV)
📊 7.1× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.25mg
25 mcg (56% DV)
✅ Within RDA (0.6× RDA of 0.045 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.025mg UL 2mg
Potassium
49.5 mg (1% DV)
18 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 18mg
6 mg
📊 Market median: 500.0mg (9 products)
This product: 6mg
375 mg
⚠️ Exceeds Tolerable Upper Intake Level by 208.3× (UL: 1.8 mg) 📚 1 studies (Tier A: 0, B: 1)
This product: 375mg UL 1.8mg

Other Ingredients

Hypromellose Water Microcrystalline Cellulose Ascorbyl Palmitate Silica Medium Chain Triglyceride Oil Mixed Tocopherols

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (71% of products) Nutrient (61% of products) Approved Health (1% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take the contents of one packet twice daily, or use as directed by your healthcare professional.

Directions: Consume the contents of one packet twice daily, or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Consult your healthcare professional prior to use. Do not use if packet is damaged.

Individuals taking medication, especially blood thinners, should discuss potential interactions with their healthcare professional.

Do not use if package is tamper seal is damaged. The labeling on this product does not comply with California's Proposition 65. Therefore, this product may not be sold in California.

🧪 Formulation Notes

Daily dose-pack nutrition

Microcrystalline hydroxyapatite concentrate.

ActivEssentials with Calcium is a combination of four targeted nutritional formulas packaged together to provide convenient and comprehensive nutritional support.

ActivNutrients without Iron: A high-quality, hypoallergenic, proprietary multivitamin/mineral blend featuring activated vitamins, including folate as 5-MTHF (5-methyltetrahydrofolate), and patented Albion chelated mineral complexes in easy-to-swallow vegetarian capsules.

Each packet contains: 2 ActivNutrients without Iron capsules, 1 Oraxinol capsule, 1 OmegaPure 600 EC softgel, and 1 Ossopan 1100 capsule.

Formulated to exclude: Wheat, gluten, yeast, soy protein, dairy products shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

Additional Information

GMP Compliant Third-party verified

This package is completely recyclable.

This unit not labeled for individual sale.

Storage: Keep closed in a cool, dry place out of reach of children.

Scan this code to learn more!

ePV (ePedigree Verification)

Xymogen supports the initiative Clean seas Turn the tide on plastic Xymogen is committed to reducing the amount of plastics used throughout our business, particularly in the packaging of out products. With our participation in the United Nations Environment Programme Clean Seas initiative, we strive to positively decrease our environmental footprint, providing results that can ultimately: Help free the ocean of litter, making it safer for millions of marine animals Reduce the use of non-renewable resources. Keep wild-caught seafood healthy and safe to eat. Protect maritime economies such as organic fishing, tourism, and recreation. We are doing our part to make a world of difference. How are you making an impact? #CleanSeas

Product Details

UPC / SKU 8 71149 00086 8
DSLD Entry Date 2024-02-22
Product Type Other Combinations
Form Capsule
Brand XYMOGEN
Bundle ActivEssentials with Calcium
DSLD ID 303582
Data Updated 2026-04-11

Research Evidence

566 Research Sources
56 Avg Quality Score
240 Meta Analysis
100 Clinical Trial
74 Systematic Review
71 Guideline
58 Rct
11 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
1 Observational
1 Openfda Safety
A Systematic review and meta-analysis of intravenous iron therapy for patients with heart failure and iron deficiency
Meta Analysis Nature medicine 2025
A Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Meta Analysis The Cochrane database of systematic reviews 2014
A Serum or plasma ferritin concentration as an index of iron deficiency and overload
Meta Analysis The Cochrane database of systematic reviews 2021
A Non-invasive diagnostic tests for Helicobacter pylori infection
Meta Analysis The Cochrane database of systematic reviews 2018
A Hypoxia-inducible factor stabilisers for the anaemia of chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2022
A Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations
Meta Analysis The Cochrane database of systematic reviews 2021
A Fortification of condiments and seasonings with iron for preventing anaemia and improving health
Meta Analysis The Cochrane database of systematic reviews 2023
A Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2024
A Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review
Meta Analysis Neuroscience and biobehavioral reviews 2025
View all evidence for Iron →

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